Abstract: The invention relates to a pharmaceutical composition and a method for treating drug addicts' withdrawal syndrome and detoxifying addicts. The pharmaceutical composition comprises aconitane derivative of formulas I, II, their inorganic acid salts or mixtures thereof, and tetrahydroprotoberberine derivatives of formula II. The method of treatment comprises administering the pharmaceutical composition to drug addicts. The pharmaceutical composition of the present invention produces no drug dependence, excellent effects, fast action and low side-effects.
Abstract: This invention relates to a medication to treat addicts who are addicted to drugs or narcotics (including opium, morphine, heroine, cocaine, marijuana, amphetamine, etc.), the preparative method of this medication, as well as the treatment method for the addicts by using this medication. This medication to treat addiction is aconitane deivative having structures of formula I or II, wherein the formula I, R=.alpha.--OCH.sub.3, .beta.--OCH.sub.3 or .alpha.--OH; R.sub.1 =OAcABz, OH, OABz or H; R.sub.2 =H or OH; R.sub.3 =H or OH; R.sub.4 =H or OH; R.sub.5 =H or OH; R.sub.6 =OCH.sub.3, OBz, OAc or OH; wherein the formula II, R.sub.1 =R.sub.2 =R.sub.3 =OH.This medication to treat addiction is characterized by no drug-dependence, high cure effect, fast action and low side effect.