Abstract: The present invention is related to a new microorganism Streptomyces exfoliatus YJ-118 and a method for producing pravastatin sodium by using this microorganism which shows a strong tolerance to ML-236B and a high hydroxylation activity of ML-236B to pravastatin.
Type:
Grant
Filed:
December 29, 1999
Date of Patent:
October 23, 2001
Assignee:
Yungjin Pharmaceutical Ind. Co., Ltd.
Inventors:
Joo-Kyung Lee, Joo-Woong Park, Dong-Jin Seo, Sang-Choon Lee, Ji-Yoon Kim