Patents Assigned to Yunnan Jici Institute for Regenerative Medicine Co., Ltd.
  • Method for inducing differentiated cell into Mesenchymal Stem Cell, and combinations of regulatory targets thereof
    Patent number: 11674122
    Abstract: A method for inducing differentiated cells into mesenchymal stem cells (MSCs), and combinations of regulatory targets thereof. The method includes performing a directional induction on the differentiated cells to prepare the mesenchymal stem cells. The directional induction includes treating cells by inhibiting the TGF-? signal pathway, inhibiting the activity of PKC, activating the WNT/?-catenin signal pathway and activating the cAMP signal pathway. By regulating corresponding signal pathways and/or enzymatic activities by stages, the differentiated cells are induced into the mesenchymal stem cells.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: June 13, 2023
    Assignee: Yunnan Jici Institute for Regenerative Medicine Co., Ltd.
    Inventors: Min Hu, Yanjiao Li
  • Method for Inducing Differentiated Cell into Mesenchymal Stem Cell, and Combinations of Regulatory Targets Thereof
    Publication number: 20190345451
    Abstract: A method for inducing differentiated cells into mesenchymal stem cells (MSCs), and combinations of regulatory targets thereof. The method includes performing a directional induction on the differentiated cells to prepare the mesenchymal stem cells. The directional induction includes treating cells by inhibiting the TGF-? signal pathway, inhibiting the activity of PKC, activating the WNT/?-catenin signal pathway and activating the cAMP signal pathway. By regulating corresponding signal pathways and/or enzymatic activities by stages, the differentiated cells are induced into the mesenchymal stem cells.
    Type: Application
    Filed: November 6, 2017
    Publication date: November 14, 2019
    Applicant: Yunnan Jici Institute for Regenerative Medicine Co., Ltd.
    Inventors: Min HU, Yanjiao LI