Patents Assigned to YUNNAN UNIVERSITY OF NATIONALITIES
  • Asymmetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities
    Patent number: 8835658
    Abstract: The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: September 16, 2014
    Assignees: Hong Kong Baptist University, Yunnan University of Nationalities
    Inventors: Albert Sun-Chi Chan, Baomin Fan, Jun Wang, Chengyuan Lin, Chao Huang, Qingjing Yang, Jianbin Xu, Zhaoxiang Bian, Aiping Lu, Jun Hu
  • ASYMETRIC SYNTHESIS OF NORCANTHARIDIN ANALOUGUS BY ALKYNYLATION OF OXABENZONORBORNADIENES AND THEIR ANTICANCER ACTIVITIES
    Publication number: 20140187801
    Abstract: The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.
    Type: Application
    Filed: December 28, 2012
    Publication date: July 3, 2014
    Applicants: YUNNAN UNIVERSITY OF NATIONALITIES, HONG KONG BAPTIST UNIVERSITY
    Inventors: Albert Sun-Chi Chan, Baomin Fan, Jun Wang, Chengyuan Lin, Chao Huang, Qingjing Yang, Jianbin Xu, Zhaoxiang Bian, Aiping Lu, Jun Hu
  • USE OF AMIDE COMPOUNDS FOR PREVENTING MARINE BIOFOULING
    Publication number: 20140044810
    Abstract: Use of amide compounds represented by formula (I), for preventing or reducing settlement and/or fouling of marine fouling organisms on a surface of a submerged object is provided, wherein “-A-” has a formula -(CnH2(n?m))- which is either unsubstituted or substituted by one or more C1 to C4 alkyls, and wherein the formula -(CnH2(n?m))- represents a divalent alkyl, or a divalent alkenyl having one or more double bonds, n is 1 to 15, m is 0 to 4, and 2(n?m)=2, and R is selected from piperidinyl, pyrrolidinyl, isobutylamino, piperazinyl or morpholinyl. Amide compounds of formula (I), a category of antifouling compounds, can be either isolated from natural resources or synthesized, which are nontoxic and environmental-friendly.
    Type: Application
    Filed: April 17, 2012
    Publication date: February 13, 2014
    Applicants: YUNNAN UNIVERSITY OF NATIONALITIES, THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Peiyuan Qian, Xiangzhong Huang, Ying Xu, Yu Zhang, Yue Him Wong, Yan Yin, Zhuang Han