Abstract: The present invention relates to a 2-aminoethanesulfonic acid zinc complex represented by the following formula: ##STR1## (wherein M is an alkali metal atom), to a process for producing the said complex from 2-aminoethanesulfonic acid and to use of the said complex as an anti-hepatitis agent, liver function improving agent and anti-ulcer agent. The said complex exhibits not only improved physiological activities such as anti-hepatitis activity, suppressory activity against liver-function disorder and anti-ulcer activity but also protective and restorative activity for the digestive tract.

Abstract: Medical articles composed of silicone rubber coated with collagen to be used in living body, are manufactured by subjecting a surface of shaped articles composed of silicone rubber to a spark discharge, coating the thus treated surface with an acidic aqueous solution of collagen and then drying said surface to form collagen layer and irradiating the shaped article coated with collagen with high energy ionizing radiation under an atmosphere having such a humidity that the water content of the coated collagen becomes more than 20% by weight.