Abstract: The invention features compositions, methods, and kits useful for the treatment of filovirus-mediated diseases, e.g., hemorrhagic fever caused by Ebola virus, in an animal.
Type:
Grant
Filed:
February 22, 2010
Date of Patent:
July 2, 2013
Assignees:
U.S. Army Medical Research and Material Command, Zalicus, Inc.
Inventors:
Lisa M. Johansen, Joseph Lehár, Benjamin G. Hoffstrom, Gene G. Olinger, Andrea R. Stossel
Abstract: The invention features methods, kits, and compositions for the treatment of ophthalmic disorders. The compositions include a corticosteroid in combination with a non-steroidal immunophilin-dependent immunosuppressant.
Type:
Application
Filed:
August 29, 2012
Publication date:
December 20, 2012
Applicant:
Zalicus, Inc.
Inventors:
Todd W. Chappell, M. James Nichols, Daniel S. Grau
Abstract: The invention features methods, kits, and compositions for the treatment of ophthalmic disorders. The compositions include a corticosteroid in combination with a non-steroidal immunophilin-dependent immunosuppressant.
Type:
Grant
Filed:
November 28, 2011
Date of Patent:
September 4, 2012
Assignee:
Zalicus, Inc.
Inventors:
Todd W. Chappell, M. James Nichols, Daniel S. Grau
Abstract: The invention features methods, kits, and compositions for the treatment of ophthalmic disorders. The compositions include a corticosteroid in combination with a non-steroidal immunophilin-dependent immunosuppressant.
Type:
Application
Filed:
November 28, 2011
Publication date:
March 29, 2012
Applicant:
Zalicus Inc.
Inventors:
Todd W. Chappell, M. James Nichols, Daniel S. Grau
Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
Type:
Application
Filed:
November 9, 2011
Publication date:
March 8, 2012
Applicant:
Zalicus Inc.
Inventors:
Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
Type:
Grant
Filed:
September 7, 2006
Date of Patent:
December 20, 2011
Assignee:
Zalicus Inc.
Inventors:
Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
Abstract: The invention features methods, kits, and compositions for the treatment of ophthalmic disorders. The compositions include a corticosteroid in combination with a non-steroidal immunophilin-dependent immunosuppressant.
Type:
Grant
Filed:
November 8, 2006
Date of Patent:
November 29, 2011
Assignee:
Zalicus Inc.
Inventors:
Todd W. Chappell, M. James Nichols, Daniel S. Grau