Patents Assigned to ZalVac AB
  • Streptococcal vaccines
    Patent number: 12350324
    Abstract: An immunogenic composition comprising bacterial membrane vesicles (MVs) comprising a streptococcal MalX antigen and/or a streptococcal PrsA antigen, characterized in that the MVs do not comprise an immunogenic amount of a streptococcal PspA antigen. The membrane vesicles may be artificial membrane particles. Medical uses of the composition in particular for immunization against pneumococcal disease, and methods of manufacturing the composition.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: July 8, 2025
    Assignee: ZalVac AB
    Inventors: Birgitta Henriques Normark, Staffan Normark, Federico Iovino, Ana Rita Narciso, Peter Mellroth
  • Microparticles from as vaccine antigens
    Patent number: 11844829
    Abstract: An isolated Streptococcus pneumoniae membrane vesicle microparticle (MP), wherein said MP comprises: the protein Ply at the level of ?0.070 ?g/?g total protein in the MP; and/or the protein LytA at the level of ?0.070 ?g/?g total protein in the MP; and/or the protein PspC at the level of ?0.130 ?g/?g total protein in the MP; and/or the protein RrgB at the level of ?0.020 ?g/?g total protein in the MP. Compositions comprising such MPs. Uses thereof in particular in immunization, as well as methods of manufacture thereof.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: December 19, 2023
    Assignee: ZalVac AB
    Inventors: Birgitta Henriques Normark, Mario Codemo, Federico Iovino, Sandra Muschiol, Staffan Normark, Sun Nyunt Wai