Patents Assigned to Zambon Group
  • Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system
    Patent number: 5674909
    Abstract: Compounds of formula ##STR1## wherein R, R', R", R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X, Y, m, n and p have the meanings reported in the description;and their pharmaceutically acceptable salts are described.The compounds of formula I are useful in the treatment of arterial hypertension and congestive heart failure, of renal failure, of peripheral arteriopathies, of cerebrovascular insufficiencies and of ischemic cardiopathy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 7, 1997
    Assignee: Zambon Group
    Inventors: Stefania Montanari, Paolo Cavalleri, Cristina Fraire, Gian Carlo Grancini, Mauro Napoletano, Francesco Santangelo
  • Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol)(2R,cis)-1,2-ep-oxipropyl-ph osphonate with improved characteristics of stability and processing
    Patent number: 5162309
    Abstract: A process is described for the preparation of mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability, of processing for the preparation of pharmaceutical forms and of stability of the pharmaceutical forms that contain it.
    Type: Grant
    Filed: July 25, 1990
    Date of Patent: November 10, 1992
    Assignee: Zambon Group
    Inventors: Dario Tentorio, Graziano Castaldi, Claudio Giordano, Franco Pozzi