Patents Assigned to Zambon S.p.A.
  • Publication number: 20210128678
    Abstract: The present invention relates to a synergistic pharmacological association of NAC and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising CF, bronchiectasis non CF and COPD.
    Type: Application
    Filed: February 26, 2018
    Publication date: May 6, 2021
    Applicant: Zambon S.P.A.
    Inventors: Lucia Pallecchi, Francesco Sergio, Gian Maria Rossolini
  • Publication number: 20210113508
    Abstract: The present invention relates to N-acetylcysteine for the use in the treatment of bacterial infections caused by a pathogen selected from Burkholderia cepacia complex (BCC) and Stenotrophomonas maltophilia (S. maltophilia) strains.
    Type: Application
    Filed: December 28, 2020
    Publication date: April 22, 2021
    Applicant: Zambon S.P.A.
    Inventors: Gian Maria Rossolini, Lucia Pallecchi, Francesco Sergio
  • Publication number: 20210030705
    Abstract: A pharmaceutical, non-effervescent, solid composition comprising a mixture of a pharmaceutically effective amount of a ibuprofen salt and a pharmaceutically acceptable strong base in a molar ratio of from 1:0.01 to 1:0.8, said composition being such that, when dissolved in drinkable water for dilution, imparts a pH value ranging from 9 to 9.5 to the obtained solution, which do not cause sensory irritation to the oral cavity especially to the back of the mouth and throat, when swallowed.
    Type: Application
    Filed: October 19, 2020
    Publication date: February 4, 2021
    Applicant: Zambon S.P.A.
    Inventors: Alberto Moretto, Alessandra De Lazzari, Lucia Dicorato
  • Publication number: 20200315969
    Abstract: The present invention relates to pharmaceutical compositions comprising safinamide and, more particularly, to taste-masked particles comprising said active ingredient or pharmaceutically acceptable salts thereof, oral dosage forms that include said particles and a process for preparing them.
    Type: Application
    Filed: October 30, 2018
    Publication date: October 8, 2020
    Applicant: Zambon S.P.A.
    Inventors: Alberto Moretto, Alessandra De Lazzari, Fabiana Mazzara
  • Patent number: 10792257
    Abstract: The present invention relates to pharmaceutical compositions comprising safinamide, and, more particularly, to taste-masked particles comprising said active ingredient or pharmaceutically acceptable salts thereof, oral dosage forms that include said particles and a process for preparing them.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: October 6, 2020
    Assignee: Zambon S.P.A.
    Inventors: Alberto Moretto, Alessandra De Lazzari, Deborah Teoli
  • Publication number: 20200093774
    Abstract: The present invention relates to N-acetylcysteine for the use in the treatment of bacterial infections caused by a pathogen selected from Burkholderia cepacia complex (BCC) and Stenotrophomonas maltophilia (S. maltophilia) strains.
    Type: Application
    Filed: December 13, 2017
    Publication date: March 26, 2020
    Applicant: Zambon S.P.A.
    Inventors: Gian Maria Rossolini, Lucia Pallecchi, Francesco Sergio
  • Publication number: 20200085769
    Abstract: The present invention relates to pharmaceutical compositions comprising safinamide, and, more particularly, to taste-masked particles comprising said active ingredient or pharmaceutically acceptable salts thereof, oral dosage forms that include said particles and a process for preparing them.
    Type: Application
    Filed: May 30, 2017
    Publication date: March 19, 2020
    Applicant: Zambon S.P.A.
    Inventors: Alberto Moretto, Alessandra De Lazzari, Deborah Teoli
  • Patent number: 10583082
    Abstract: The present invention relates to inhalation formulations of drugs in the form of dry powder for inhalation administration deliverable as such with an inhaler and provided with high deliverability, respirability and stability. In particular, the invention relates to a pharmaceutical composition for inhalation in the form of powder comprising at least a first and a second powder, in which at least said first powder contains an active agent in an amount greater than 1% by weight with respect to the weight of said first powder. Both the powders comprise leucine in an amount ranging from 5 to 70% by weight with respect to the weight of each powder and a sugar in an amount ranging from 20 to 90% by weight with respect to the weight of each powder. The composition has a fine particle fraction (FPF) greater than 60% and a delivered fraction (DF) greater than 80.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: March 10, 2020
    Assignee: ZAMBON S.P.A.
    Inventors: Giovanni Caponetti, Loretta Maggi, Cristina Veneziani, Paolo Ventura, Laura Zanellotti
  • Patent number: 10517828
    Abstract: The present invention relates to inhalation formulations of drugs in the form of dry powder for inhalation administration deliverable as such with an inhaler and provided with high deliverability, respirability and stability. In particular, the invention relates to a pharmaceutical composition for inhalation use in powder form comprising a first powder comprising at least a powder (a1) comprising an active agent or a pharmaceutically acceptable salt thereof, in an amount greater than 1% by weight of the powder, leucine in an amount from 5 to 70% by weight of said powder, a sugar in an amount from 20 to 90% by weight of the powder; and a second powder comprising a mixture of a first lactose which has an X50 from 35 to 75 ?m, with a second lactose which has an X50 from 1.5 to 10 ?m, the content of the first and second lactose in the mixture are respectively from 85% to 96% and from 4% to 15%.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: December 31, 2019
    Assignee: ZAMBON S.P.A.
    Inventors: Loretta Maggi, Giovanni Caponetti, Heike Butti, Cristina Veneziani, Laura Zanellotti
  • Patent number: 10449147
    Abstract: The present invention relates to inhalation formulations of drugs in the form of dry powder for inhalation administration, suitable for the treatment of obstructive diseases of the airways, such as asthma and chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: October 22, 2019
    Assignee: Zambon S.P.A.
    Inventors: Loretta Maggi, Giovanni Caponetti, Marco Sardina, Franco Castegini
  • Publication number: 20190156959
    Abstract: A method, a communication system and a computer program for providing information indicative of concentration of allergens in the environment. A person detecting a respiratory difficulty symptom (presumably due to the presence of an allergen in the environment) records information relating to the detected symptom using her/his mobile device. The recording comprises providing subjective information relating to the detected respiratory difficulty symptom via a graphical interface of the mobile device. The mobile device completes the information relating to the detected symptom with automatically generated objective information (date and time). Then, at least part of the recorded information relating to the detected symptom is shared by the mobile device on a sharing server. Any other mobile device may receive the share part of the recorded information relating to the detected symptom from the sharing server and display it on a map shown by its display.
    Type: Application
    Filed: May 8, 2017
    Publication date: May 23, 2019
    Applicant: ZAMBON S.p.A.
    Inventor: Massimiliano MUZIO
  • Patent number: 10226421
    Abstract: The present invention relates to drug formulations in dry powder form for administration by inhalation and indicated for the treatment of obstructive airway syndromes such as asthma and chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: March 12, 2019
    Assignee: Zambon S.P.A.
    Inventors: Giovanni Caponetti, Loretta Maggi, Marco Sardina, Franco Castegini, Gianluigi Faiella, Daniela Rebolini
  • Patent number: 9808427
    Abstract: This invention relates to swallowable tablets containing at least 80% by weight of N-acetylcysteine (NAC) and at least one pharmaceutically acceptable excipient, in particular tablets in which the sulfurous odor is absent, characterized in that the said tablets are assembled using a granulate prepared by means of a process of dry granulating the active ingredient alone, with which the excipients are mixed before compression.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: November 7, 2017
    Assignee: ZAMBON S.P.A.
    Inventors: Alessandra De Lazzari, Alberto Moretto
  • Publication number: 20160081925
    Abstract: The present invention relates to drug formulations in dry powder form for administration by inhalation and indicated for the treatment of obstructive airway syndromes such as asthma and chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: April 9, 2014
    Publication date: March 24, 2016
    Applicant: Zambon S.P.A.
    Inventors: Giovanni Caponetti, Loretta Maggi, Marco Sardina, Franco Castegini, Gianluigi Faiella, Daniela Rebolini
  • Patent number: 9248151
    Abstract: The present invention relates to topical vaginal compositions in gel form containing immune mediators, growth factors, chemotactic factors and antibacterial/antiviral factors extracted from bovine colostrum, and optionally other ingredients with complementary activity.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: February 2, 2016
    Assignee: ZAMBON S.P.A.
    Inventors: Alberto Bartorelli, Maria Rosa Gobbi
  • Patent number: 8927017
    Abstract: A method for preparing a gabapentin granulate comprising melt granulating gabapentin with polyethylene glycol having a melting point comprised between 50 and 80° C.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: January 6, 2015
    Assignee: ZAMBON S.p.A.
    Inventors: Luca Rampoldi, Alessandro Grassano
  • Publication number: 20140322329
    Abstract: The present invention relates to topical vaginal compositions in gel form containing immune mediators, growth factors, chemotactic factors and antibacterial/antiviral factors extracted from bovine colostrum, and optionally other ingredients with complementary activity.
    Type: Application
    Filed: December 2, 2011
    Publication date: October 30, 2014
    Applicant: ZAMBON S.P.A.
    Inventors: Alberto Bartorelli, Maria Rosa Gobbi
  • Patent number: 8522774
    Abstract: An aerosol apparatus including a nebulizer device and a mask suitable for receiving a substance substantially in the sol state from the nebulizer device is described. The apparatus also includes a display device able to display a sequence of images to a patient while he/she is using the apparatus. The display device may be a DVD player which conveniently is able to be separated from the aerosol apparatus. The apparatus is particularly suitable for use by patients who are children.
    Type: Grant
    Filed: June 12, 2007
    Date of Patent: September 3, 2013
    Assignee: Zambon S.p.A.
    Inventors: Elena Zambon, Gianluca Basso
  • Patent number: 8287846
    Abstract: The present invention relates to odour improved dermatological or cosmetic preparations comprising N-acetylcysteine and a polyol system containing one or more polyols as masking odour agents. The emulsions of the present invention are useful in the treatment of dermatological disorders or cosmetic skin conditions.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: October 16, 2012
    Assignee: ZAMBON S.p.A.
    Inventors: Luca Rampoldi, Alberto Moretto, Alessandro Grassano
  • Patent number: 7956042
    Abstract: The present invention relates to macrolide compounds endowed with antiinflammatory activity and more particularly relates to new stable crystalline forms of a macrolide derivative with antiinflammatory activity, processes for the preparation of such forms, pharmaceutical compositions containing them as active ingredient and the use of said crystalline forms for the treatment of inflammatory diseases.
    Type: Grant
    Filed: July 5, 2006
    Date of Patent: June 7, 2011
    Assignee: Zambon S.p.A.
    Inventors: Paolo Maragni, Dario Braga, Roberto Brescello, Livius Cotarca, Alessandro Di Maria, Franco Massaccesi, Elisa Melotto, Ivan Michieletto, Gabriele Morazzoni, Mauro Napoletano, Franco Pellacini, Angelo Restelli, Massimo Verzini