Abstract: The present disclosure provides, inter alia, RAF-Degrading Conjugate Compounds that are useful in the treatment of cancer and other RAF related diseases. Also provided are, pharmaceutical compositions, methods of treatment, and kits comprising a RAF-Degrading Conjugate Compound.
Type:
Grant
Filed:
April 27, 2018
Date of Patent:
September 29, 2020
Assignee:
ZAMBONI CHEM SOLUTIONS INC.
Inventors:
Robert Zamboni, Ryan Henning, Xian Alan Ji, Tyler Smith, Bradley Heller, Thumkunta Jagadeeswar Reddy, Sylvain Rocheleau, Marc Andre Beaulieu