Patents Assigned to Zealand Pharma A/S
-
Patent number: 11957761Abstract: Compounds of formula (1): and pharmaceutically acceptable salts and solvates thereof, are described. The compounds are ?4?7 antagonists and are useful in the prevention or treatment of inflammatory conditions and/or autoimmune diseases, especially inflammatory bowel disease.Type: GrantFiled: December 20, 2022Date of Patent: April 16, 2024Assignee: Zealand Pharma A/SInventor: Stefan Schunk
-
Publication number: 20240067696Abstract: The present invention relates to glucagon analogues and their medical use, for example in the treatment of hypoglycaemia. In particular, the present invention relates to stable glucagon analogues suitable for use in a liquid formulation.Type: ApplicationFiled: September 21, 2023Publication date: February 29, 2024Applicant: Zealand Pharma A/SInventors: Ditte RIBER, Lise GIEHM
-
Patent number: 11884713Abstract: The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.Type: GrantFiled: July 7, 2021Date of Patent: January 30, 2024Assignee: Zealand Pharma A/SInventors: Ditte Riber, Jakob Lind Tolborg, Dieter Wolfgang Hamprecht, Wolfgang Rist
-
Patent number: 11814417Abstract: The present invention relates to acylated GIP analogues which have GIP agonist activity, and their use in the treatment of metabolic disorders.Type: GrantFiled: April 2, 2021Date of Patent: November 14, 2023Assignee: Zealand Pharma A/SInventors: Anne Pernille Tofteng Shelton, Pia Nørregaard, Maria Alexandrovna Deryabina, Bjarne Due Larsen, Jacob Ulrik Fog
-
Patent number: 11795204Abstract: The present invention relates to glucagon analogues and their medical use, for example in the treatment of hypoglycaemia. In particular, the present invention relates to stable glucagon analogues suitable for use in a liquid formulation.Type: GrantFiled: September 11, 2019Date of Patent: October 24, 2023Assignee: Zealand Pharma A/SInventors: Ditte Riber, Lise Giehm
-
Patent number: 11780893Abstract: The present invention provides novel blockers of the potassium channel Kv1.3, polynucleotides encoding them, and methods of making and using them.Type: GrantFiled: February 24, 2022Date of Patent: October 10, 2023Assignee: Zealand Pharma A/SInventors: Henrik Fischer Munch, Rasmus Bugge Jensen, Jens Kvist Madsen
-
Patent number: 11713338Abstract: There is described herein, multimers comprising a plurality of compounds covalently linked together, the compounds independently being of formula (I).Type: GrantFiled: April 19, 2021Date of Patent: August 1, 2023Assignee: Zealand Pharma A/SInventors: Mohammed Monzur Morshed, Sai Kumar Chakka, Jennifer L. Hickey, Manuel Perez Vazquez, Andrew Roughton, Adam Paul Kafal, Narendrakumar B. Patel
-
Publication number: 20220313902Abstract: Embodiments of this invention relate to a fluid delivery device. The fluid delivery device comprises a fluid reservoir for containing a fluid, a first drive mechanism configured to remove a predetermined amount of the fluid from the fluid reservoir when the first drive mechanism is actuated, a needle, a septum and a housing having an orifice. Also disclosed is a method for dispensing a fluid from a fluid delivery device into a patient.Type: ApplicationFiled: June 16, 2022Publication date: October 6, 2022Applicant: Zealand Pharma A/SInventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
-
Publication number: 20220296471Abstract: An adapter (650) for transferring fluid between a first device (100) and a second device (800). The adapter comprises a first end (652) for receiving the first device, wherein the first end includes a side wall for locating around the first device (100). The adapter (650) further comprises a second end (654) for engaging the first device (100), and including a retaining member (656; 658; 662), wherein the retaining member (656; 658; 662) is operable to prevent removal of the first device (100) from the adapter (650) upon engagement of the first device (100) with the second end (654). The first end (652) and the second end (654) are open on both ends to comprise a through-bore extending through the adapter (650). In some cases, the first device (100) may be a drug pen containing insulin.Type: ApplicationFiled: August 5, 2020Publication date: September 22, 2022Applicant: ZEALAND PHARMA A/SInventors: Christopher GREGORY, Michael BARENBOYM
-
Patent number: 11395847Abstract: A compound having agonist activity at the GLP-1 (glucagon-like-peptide 1) and GLP-2 (glucagon-like peptide 2) receptors, and a pharmaceutical composition containing the compound or a pharmaceutically acceptable salt or solvate thereof in admixture with a pharmaceutically acceptable carrier, an excipient or a vehicle are provided. The compound can be used, inter alia, in the prophylaxis or treatment of intestinal damage and dysfunction, regulation of body weight, and prophylaxis or treatment of metabolic dysfunction.Type: GrantFiled: April 6, 2020Date of Patent: July 26, 2022Assignee: Zealand Pharma A/SInventors: Bjarne Due Larsen, Jonathan Griffin, Lise Giehm, Alistair Vincent Gordon Edwards
-
Patent number: 11382956Abstract: The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes. The analogues have good physical and chemical stability, good solubility, and a long duration of action, and are well suited for use in the form of a liquid formulation.Type: GrantFiled: October 25, 2019Date of Patent: July 12, 2022Assignee: Zealand Pharma A/SInventors: Jesper Mosolff Mathiesen, Jesper Skodborg Villadsen, Lise Giehm, Henrik Kofoed Munch, Dieter Wolfgang Hamprecht, Alexander Heim-Riether, Giacomo Fossati
-
Publication number: 20220160959Abstract: A medicament delivery device may comprise a medicament chamber configured to hold a medicament, a plunger configured to move relative to the medicament chamber to expel the medicament from the medicament chamber, a pin configured to move from a first pin position wherein the pin prevents movement of the plunger to a second pin position wherein the pin allows movement of the plunger, an actuation assembly configured to move the pin from the first pin position to the second pin position, and a needle coupled to the medicament chamber. The medicament may flow through the needle from the medicament chamber to a user. The actuation assembly may be configured to automatically move the pin after a predetermined time delay.Type: ApplicationFiled: February 11, 2022Publication date: May 26, 2022Applicant: Zealand Pharma A/SInventors: Christopher Gregory, Geoffrey Jenkins
-
Patent number: 11324799Abstract: The use of gap junction intercellular communication (GJIC) modulators in the treatment or prevention of diabetic eye disease is disclosed, and more particularly to their use for the treatment or prevention of early stage diabetic retinopathy and diabetic macular edema by inhibiting apoptosis of retinal endothelial cells and inhibiting pericyte loss.Type: GrantFiled: May 4, 2018Date of Patent: May 10, 2022Assignees: ZEALAND PHARMA A/S, BOSTON MEDICAL CENTER CORPORATIONInventors: Bjarne Due Larsen, Ulrik Mouritzen, Dongjoon Kim, Sayon Roy
-
Patent number: 11292820Abstract: The present invention provides novel blockers of the potassium channel Kv1.3, polynucleotides encoding them, and methods of making and using them.Type: GrantFiled: June 23, 2021Date of Patent: April 5, 2022Assignee: Zealand Pharma A/SInventors: Henrik Fischer Munch, Rasmus Bugge Jensen, Jens Kvist Madsen
-
Patent number: 11286281Abstract: There is described herein antagonists of ?4?7 integrin, and more particularly cyclic peptide antagonists, such as compounds of formula (I).Type: GrantFiled: May 10, 2018Date of Patent: March 29, 2022Assignee: Zealand Pharma A/SInventors: Manuel Perez Vazquez, M. Monzur Morshed, Adam Paul Kafal, Jennifer L. Hickey, Andrew Roughton
-
Patent number: 11278667Abstract: A medicament delivery device may comprise a medicament chamber configured to hold a medicament, a plunger configured to move relative to the medicament chamber to expel the medicament from the medicament chamber, a pin configured to move from a first pin position wherein the pin prevents movement of the plunger to a second pin position wherein the pin allows movement of the plunger, an actuation assembly configured to move the pin from the first pin position to the second pin position, and a needle coupled to the medicament chamber. The medicament may flow through the needle from the medicament chamber to a user. The actuation assembly may be configured to automatically move the pin after a predetermined time delay.Type: GrantFiled: June 20, 2018Date of Patent: March 22, 2022Assignee: ZEALAND PHARMA A/SInventors: Christopher Gregory, Geoffrey Jenkins
-
Patent number: 11274136Abstract: The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.Type: GrantFiled: May 13, 2019Date of Patent: March 15, 2022Assignee: Zealand Pharma A/SInventors: Ditte Riber, Jakob Lind Tolborg, Dieter Wolfgang Hamprecht, Leo Thomas
-
Publication number: 20220016334Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.Type: ApplicationFiled: October 1, 2021Publication date: January 20, 2022Applicant: Zealand Pharma A/SInventors: Robert R. GONNELLI, Steven F. LEVESQUE, Ronald V. NARDI
-
Patent number: D935604Type: GrantFiled: February 25, 2021Date of Patent: November 9, 2021Assignee: ZEALAND PHARMA A/SInventors: Christopher Gregory, Geoffrey Jenkins, Matthew Johnson
-
Patent number: D955566Type: GrantFiled: July 1, 2020Date of Patent: June 21, 2022Assignee: ZEALAND PHARMA A/SInventors: Christopher Gregory, Geoffrey Jenkins, Matthew Johnson