Patents Assigned to Zeneca
  • APC gene and nucleic acid probes derived therefrom
    Patent number: RE36713
    Abstract: A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in hum tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as wel as in sporadic colorectal cancer patents. APC is expressed in most normal tissue. These results suggest that APC is a tumor suppressor.
    Type: Grant
    Filed: October 4, 1996
    Date of Patent: May 23, 2000
    Assignees: The Johns Hopkins University, The University of Utah, Zeneca, Cancer Institute
    Inventors: Bert Vogelstein, Kenneth W. Kinzler, Hans Albertson, Rakesh Anand, Mary Carlson, Joanna Groden, Philip John Hedge, Geoff Joslyn, Alexander Fred Markham, Yusuke Nakamura, Andrew Thliveris, Raymond White