Patents Assigned to Zeneca Pharmaceuticals
  • APC (adenomatous polyosis coli) protein
    Patent number: 5783666
    Abstract: A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: July 21, 1998
    Assignees: The Johns Hopkins University, The University of Utah, Zeneca Pharmaceuticals, The Cancer Institute
    Inventors: Hans Albertsen, Rakesh Anand, Mary Carlson, Joanna Groden, Philip John Hedge, Geoff Joslyn, Kenneth Kinzler, Alexander Fred Markham, Yusuke Nakamura, Andrew Thliveris, Bert Vogelstein, Raymond L. White