Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
Type:
Application
Filed:
June 20, 2014
Publication date:
June 30, 2016
Applicant:
ZENITH EPIGENETICS CORP.
Inventors:
Shuang LIU, John Frederick QUINN, Bryan Cordell DUFFY, Ruifang WANG, May Xiaowu JIANG, Gregory Scott MARTIN, He ZHAO, Michael ELLIS, Gregory Steven WAGNER, Peter Ronald YOUNG
Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
Type:
Grant
Filed:
June 3, 2015
Date of Patent:
March 8, 2016
Assignee:
Zenith Epigenetics Corp.
Inventors:
David John Fairfax, Bryan Cordell Duffy, Gregory Scott Martin, John Frederick Quinn, Shuang Liu, Gregory Steven Wagner, Peter Ronald Young
Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
Type:
Grant
Filed:
December 19, 2013
Date of Patent:
March 1, 2016
Assignee:
Zenith Epigenetics Corp.
Inventors:
Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
Type:
Application
Filed:
June 3, 2015
Publication date:
December 3, 2015
Applicant:
Zenith Epigenetics Corp.
Inventors:
David John Fairfax, Bryan Cordell Duffy, Gregory Scott Martin, John Frederick Quinn, Shuang Liu, Gregory Steven Wagner, Peter Ronald Young
Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
Type:
Grant
Filed:
November 20, 2013
Date of Patent:
July 7, 2015
Assignee:
Zenith Epigenetics Corp.
Inventors:
David John Fairfax, Bryan Cordell Duffy, Gregory Scott Martin, John Frederick Quinn, Shuang Liu, Gregory Steven Wagner, Peter Ronald Young