Abstract: Provided is an immunostimulator containing: chitosan and/or a chitosan derivative each having a weight-average molecular weight of 10k to 1000k; and an anionic surfactant, the immunostimulator being in particulate form. Also provided are a pharmaceutical composition and an alimentary product, each containing the immunostimulator as an active ingredient.

Abstract: In one embodiment, the present invention provides a method for a plurality of cells comprising screening of a part of the cells without subculturing all of the cells and selecting a part of the cells based on the results. In one embodiment, the present invention relates to a method of producing a culture cell, comprising the steps of: a) culturing a plurality of animal cells or plant cells in a culture vessel by adherent culture or on a semisolid medium to form a plurality of colonies each of which is derived from a single cell; b) detecting a sequence of one or more base(s) in a nucleic acid for a part of said plurality of colonies by a nucleic acid or protein detection method, during which said plurality of colonies are cultured in a culture vessel; and c) selecting and collecting said part of the colonies based on the results of said detection method.

Abstract: The present invention provides a cancer cell-specific anti-podoplanin antibody or an antigen-binding fragment thereof having an epitope in a Thr85-containing region of an amino acid sequence of human podoplanin represented by SEQ ID NO: 1, the Thr85 having a sialylated O-glycan added thereto.