Patents Assigned to ZENYAKU KOGYO CO., LTD.
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Patent number: 8647630Abstract: A safe and efficient recombinant mite allergen is provided as a therapeutic agent or a diagnostic agent for mite allergic diseases, which contains no anaphylaxis-inducing impurities. The following recombinant protein (a) or (b) is provided: (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2 or 35; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 or 35 by deletion, substitution, or addition of one or several amino acids and having mite allergen activity.Type: GrantFiled: September 12, 2011Date of Patent: February 11, 2014Assignee: Nippon Zenyaku Kogyo Co., Ltd.Inventors: Toshihiro Tsukui, Hajime Tsujimoto, Shigehiro Iwabuchi
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Patent number: 8460926Abstract: To provide an aqueous solution for cell preservation which is free of a natural animal-derived component such as a basal medium or serum. An aqueous preservation solution showing a high cell survival rate was obtained by removing a natural animal-derived component such as a basal medium or serum and controlling other components and their concentrations.Type: GrantFiled: November 17, 2006Date of Patent: June 11, 2013Assignee: Nippon Zenyaku Kogyo Co., LtdInventors: Naoto Yamashiro, Kohichi Saze, Osamu Ohneda, Masumi Nagano
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Patent number: 8415163Abstract: Disclosed is a method of diagnosing renal dysfunction in a cat by removing cauxin from cat urine and detecting a protein in the cat urine sample from which cauxin has been removed. Cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or with an anti-cauxin antibody that specifically binds to cauxin. Cauxin may be removed using a column filled with a carrier that is bound to the lectin or to the anti-cauxin antibody. The lectin may be Lens culinaris lectin. Detection of the cat urinary protein from which cauxin has been removed is performed with a urine test strip.Type: GrantFiled: August 16, 2012Date of Patent: April 9, 2013Assignees: Incorporated National University Iwate University, Nippon Zenyaku Kogyo Co., Ltd.Inventors: Tetsuro Yamashita, Yasuyuki Suzuta
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Publication number: 20130034731Abstract: The present invention is directed to providing a method for preparing a vaccine adjuvant composition containing ?-hematin and a vaccine adjuvant composition obtained by the preparation method. The present invention is directed to a vaccine adjuvant composition containing a ?-hematin crystal having an average particle size of 20 to 500 nm.Type: ApplicationFiled: December 17, 2010Publication date: February 7, 2013Applicants: NIPPON ZENYAKU KOGYO CO., LTD., OSAKA UNIVERSITYInventors: Shizuo Akira, Ken Ishii, Cevayir Coban, Toshihiro Tsukui, Yoshikatsu Igari, Keiichi Ohata
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Publication number: 20120309110Abstract: A method for diagnosing a kidney disease in a cat by detecting a cat urinary protein without being affected by cauxin, and a diagnostic agent therefor are provided. A method of detecting a urinary protein derived from renal dysfunction in a cat according to claim 1, wherein cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or an anti-cauxin antibody that specifically binds to cauxin.Type: ApplicationFiled: August 16, 2012Publication date: December 6, 2012Applicants: NIPPON ZENYAKU KOGYO CO., LTD., INCORPORATED NATIONAL UNIVERSITY IWATE UNIVERSITYInventors: Tetsuro YAMASHITA, Yasuyuki Suzuta
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Publication number: 20120289679Abstract: A safe and efficient recombinant mite allergen is provided as a therapeutic agent or a diagnostic agent for mite allergic diseases, which contains no anaphylaxis-inducing impurities. The following recombinant protein (a) or (b) is provided: (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2 or 35; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 or 35 by deletion, substitution, or addition of one or several amino acids and having mite allergen activity.Type: ApplicationFiled: September 12, 2011Publication date: November 15, 2012Applicant: NIPPON ZENYAKU KOGYO CO., LTD.Inventors: Toshihiro TSUKUI, Hajime TSUJIMOTO, Shigehiro IWABUCHI
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Patent number: 8268639Abstract: A method for diagnosing a kidney disease in a cat by detecting a cat urinary protein without being affected by cauxin, and a diagnostic agent therefor are provided. A method of detecting a urinary protein derived from renal dysfunction in a cat according to claim 1, wherein cauxin is removed from cat urine by bringing the cat urine into contact with a lectin or an anti-cauxin antibody that specifically binds to cauxin.Type: GrantFiled: July 20, 2007Date of Patent: September 18, 2012Assignees: Incorporated National University Iwate University, Nippon Zenyaku Kogyo Co., Ltd.Inventors: Tetsuro Yamashita, Yasuyuki Suzuta
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Patent number: 8075898Abstract: A safe and efficient recombinant mite allergen is provided as a therapeutic agent or a diagnostic agent for mite allergic diseases, which contains no anaphylaxis-inducing impurities. The following recombinant protein (a) or (b) is provided: (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2 or 35; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 or 35 by deletion, substitution, or addition of one or several amino acids and having mite allergen activity.Type: GrantFiled: April 7, 2005Date of Patent: December 13, 2011Assignee: Nippon Zenyaku Kogyo Co., Ltd.Inventors: Toshihiro Tsukui, Hajime Tsujimoto, Shigehiro Iwabuchi
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Publication number: 20110091490Abstract: This invention provides vaccines against canine distemper virus infections, canine adenovirus type 2 infections, and canine parvovirus infections that can be orally administered. The invention also provides the attenuated canine distemper virus strain obtained by adapting the canine distemper virus 95-54 strains in cultured cells to attenuate the same, the attenuated canine adenovirus type 2 strain obtained by adapting the canine adenovirus type 2 F1 strain in cultured cells to attenuate the same, and an attenuated canine parvovirus strain obtained by adapting the canine parvovirus F3 strain in cultured cells to attenuate the same.Type: ApplicationFiled: September 13, 2007Publication date: April 21, 2011Applicant: NIPPON ZENYAKU KOGYO CO., LTD.Inventors: Masayuki Okazaki, Takahiro Yoshimura, Toshihiro Tsukui, Shigehiro Iwabuchi
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Publication number: 20100247568Abstract: The present invention provides a vaccine adjuvant composition which is used in combination with an allergen vaccine, infection vaccine or tumor vaccine.Type: ApplicationFiled: October 31, 2008Publication date: September 30, 2010Applicants: NIPPON ZENYAKU KOGYO CO., LTD., OSAKA UNIVERSITYInventors: Toshihiro Tsukui, Ken Ishii, Shizuo Akira, Cevayir Coban
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Publication number: 20090181121Abstract: ?-Aminobutyric acid is supplied to animal efficiently and inexpensively to effectively enhance stress-relieving effect on the animal. Livestock are allowed to lick ?-Aminobutyric acid mixed with molasses and solidified into feedstuff blocks, so that ?-aminobutyric acid is supplied to livestock together with molasses.Type: ApplicationFiled: May 23, 2005Publication date: July 16, 2009Applicant: NIPPON ZENYAKU KOGYO CO., LTD.Inventors: Masanori Matsunaga, Kohichi Saze, Tomio Matsunaga, Yasuyuki Suzuta
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Publication number: 20090142830Abstract: To provide an aqueous solution for cell preservation which is free of a natural animal-derived component such as a basal medium or serum. An aqueous preservation solution showing a high cell survival rate was obtained by removing a natural animal-derived component such as a basal medium or serum and controlling other components and their concentrations.Type: ApplicationFiled: November 17, 2006Publication date: June 4, 2009Applicant: NIPPON ZENYAKU KOGYO CO., LTD.Inventors: Naoto Yamashiro, Kohichi Saze, Osamu Ohneda, Masumi Nagano
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Publication number: 20090005448Abstract: Disclosed is infusion for mastitis which contains a main ingredient, medium-chain fatty acid monoglyceride and an oily base wherein diffusivity and dispersivity of the main ingredient are improved by the monoglyceride to enhance dissolubility and thus absorbency of the main ingredient. In comparison with conventional infusions for mastitis, the infusion has immediate effectivity and is short in residual term; the main ingredient is expected to be utilized effectively and without waste.Type: ApplicationFiled: January 18, 2006Publication date: January 1, 2009Applicant: Nippon Zenyaku Kogyo Co., LtdInventors: Junko Tsukada, Eiichi Ohashi, Tomio Matsunaga