Abstract: The present invention provides 2,6-dinitrogen-containing substituted purine compounds of formula (A) or salts or solvates thereof or the solvates of salts thereof, as well as pharmaceutical compositions containing such compounds. The compounds of the present invention have the characteristics of lower toxicity, broad anticancer spectrum, higher anticancer activity, good stability and the like. The compounds are useful for the manufacture of an antitumor medicament. The present invention also provides a process for preparing these compounds.
Type:
Grant
Filed:
April 17, 2008
Date of Patent:
November 12, 2013
Assignees:
Zhanggui Wu, Zhe Jiang Medicine Co., Ltd
Inventors:
Zhanggui Wu, Weidong Ye, Jianyong Yuan, Gang Chen