Abstract: An electric spraying device includes a spray emitter made of electrically conductive material, an electrode container made of electrically conductive material, and a voltage source. The electrode container has an opening at an upper end thereof, and the voltage source has a first pole electrically coupled to the spray emitter and a second pole electrically coupled to the electrode container. The spray emitter has an exit end disposed at or within the opening of the electrode container. The exit end of the spray emitter has a surface with a set of projections extending therefrom, and the set of projections are configured to form a concentrated electric field in response to an applied voltage from the voltage source between the first pole and the second pole. The spray emitter is constructed and arranged to conduct liquid along the surface to the set of projections, so as to polarize the liquid under the concentrated electric field and to dispense the liquid into the electrode container.

Abstract: A laser desorption electrospray ionization source includes a sample platform configured to support a sample material to be analyzed, an ion transfer tube having a first end and a second end, the first end facing in a direction of the sample platform, the second end connected to a mass spectrometer for providing sample molecules for spectral analysis, and a hollow emission needle having a tip that forms an electrospray nozzle, the tip extending to or into the first end of the ion transfer tube, such that the sample molecules pass the tip of the hollow emission needle on their way to the mass spectrometer.

Abstract: An ionization source for Electrospray Ionization (ESI) mass spectrometry includes a mass spectrometer having a source vacuum chamber having an inlet and an outlet. The outlet is disposed at an opening of the mass spectrometer. The ionization source further includes a hollow emission needle having an exit disposed at the inlet of the vacuum chamber. The hollow emission needle is configured to convey a first material toward the exit. An auxiliary line is disposed adjacent to the hollow emission needle to convey a second material toward the exit. A voltage supply apparatus is applied between the hollow emission needle and the mass spectrometer to establish a voltage between the hollow emission needle and the mass spectrometer and to induce particles to enter the mass spectrometer for analysis.