Abstract: The present invention relates to a process of a chemically synthetic drug, and in particular, to a new intermediate of a heparin pentasaccharide and a preparation method thereof. The process has high reaction efficiency, and an easy reaction operation. The reaction intermediate is easy to be purified, and is appropriate for an industrialization production.
Type:
Grant
Filed:
April 2, 2013
Date of Patent:
April 18, 2017
Assignee:
Zhejiang Hisum Pharmaceutical Co., Ltd.
Inventors:
Yanghui Guo, Hegeng Wei, Hua Bai, Yingqiu Wu, Yue Zhang, Junhui Zhou, Yili Ding, Lingwei Bai, Shibao Yang