Patents Assigned to Zhejiang Hisun Pharamceutical Co., Ltd.
  • Method for preparing linezolid intermediate
    Patent number: 9434702
    Abstract: Disclosed is a new method for preparing a methyl substitute of a linezolid intermediate, (S)-2-(3-(3-fluoro-4-morpholinophenyl)-2-oxo-5-oxazoline) (I), wherein the intermediate (I) is obtained by the cyclization of 3-fluoro-4-morpholinophenyl isocyanate (II) and epoxy compound (III). This process has a short process route, low cost, easy operation, and high yield, so is suitable for a large-scale industrial production.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: September 6, 2016
    Assignees: Zhejiang Hisun Pharamceutical Co., Ltd., Shanghai Institute of Pharmaceutical Industry
    Inventors: Fuli Zhang, Chunbo Yang, Bin Liang, Pengcheng Qiu, Hairong Luo, Jiang Li, Jian Chai, Qingfeng Cai