Abstract: The present invention relates to a crystalline form of entecavir and its process for preparation, and provides a pharmaceutical composition comprising a therapeutically effective amount of the crystalline form of entecavir. Furthermore, the present invention also provides a use of the crystalline form of entecavir in preparation for a medicament for the treatment of hepatitis B viral infections. The present invention is beneficial toe preparations for pharmaceutical formulations and enhancements of its bioavailability.
Type:
Grant
Filed:
January 31, 2008
Date of Patent:
January 20, 2015
Assignee:
Zhejiang Medicine Co., Ltd. Xinchang Pharaceutical Factory
Inventors:
Weidong Ye, Jianyong Yuan, Jingjing Nie, Duanjun Xu, Chaotian Chen