Patents Assigned to ZHEJIANG TERUISI PHARMACEUTICAL INC.
  • Anti-PD-1 nano-antibody and application thereof
    Patent number: 11292841
    Abstract: An anti-PD-1 nano-antibody capable of blocking a binding interaction between PD-1 and a ligand thereof, PD-L1. Disclosed are the nano-antibody, a nucleotide sequence encoding the nano-antibody, a corresponding expression vector, a host cell expressing the nano-antibody, and a method of producing the nano-antibody. Also disclosed is a humanized PD-1 nano-antibody sequence. The humanized nano-antibody can block the binding interaction between PD-1 and the ligand thereof, PD-L1 while still retaining a high affinity.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: April 5, 2022
    Assignee: ZHEJIANG TERUISI PHARMACEUTICAL INC.
    Inventors: Youling Wu, Yujie Zhang, Xiaolin Chen, Binbin Shen, Xiaoning Shen