Patents Assigned to Zhejiang Yongning Pharmaceutical Co., Ltd.
  • Patent number: 9624254
    Abstract: A new pharmaceutically acceptable salt of hydroxysafflor yellow A as presented in formula (I), in particular new monomer compounds of potassium, ammonium, calcium, and magnesium salts of hydroxysafflor yellow A, preparation method therefor, and medical uses thereof are provided. Compared to hydroxysafflor yellow A, the hydroxysafflor yellow A pharmaceutical salts of the present invention have a purity of at least 98% and are monomer compounds that are safer, more effective, stable, and controllable. The salts have the effects against PAF- or ADP-induced platelet aggregation, and can be used in treating blood circulatory disorders such as platelet aggregation, coronary artery diseases, angina, and acute cerebral ischemia to the effect comparable to hydroxysafflor yellow A, wherein, n and M are defined as in the description.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: April 18, 2017
    Assignee: ZHEJIANG YONGNING PHARMACEUTICAL CO., LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Patent number: 9243019
    Abstract: A hydroxysafflor yellow A sodium compound as shown in a formula (I) and preparation as well as medicinal application thereof are provided. According to the present invention, the safflower is utilized as a raw material. A monomer pharmaceutical compound, the hydroxysafflor yellow A sodium, is obtained by sufficient processes, and a purity thereof is surely above 98.5%. Therefore, the hydroxysafflor yellow A sodium is a monomer compound, which is safer, more effective, more stable and more controllable than hydroxysafflor yellow A, for treating blood circulation disorders such as platelet aggregation, coronary heart disease, angina pectoris and acute cerebral ischemia. Furthermore, the hydroxysafflor yellow A sodium has sufficient solubility and human tolerance.
    Type: Grant
    Filed: June 8, 2013
    Date of Patent: January 26, 2016
    Assignee: ZHEJIANG YONGNING PHARMACEUTICAL CO LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Publication number: 20150025030
    Abstract: A hydroxysafflor yellow A sodium compound as shown in a formula (I) and preparation as well as medicinal application thereof are provided. According to the present invention, the safflower is utilized as a raw material. A monomer pharmaceutical compound, the hydroxysafflor yellow A sodium, is obtained by sufficient processes, and a purity thereof is surely above 98.5%. Therefore, the hydroxysafflor yellow A sodium is a monomer compound, which is safer, more effective, more stable and more controllable than hydroxysafflor yellow A, for treating blood circulation disorders such as platelet aggregation, coronary heart disease, angina pectoris and acute cerebral ischemia. Furthermore, the hydroxysafflor yellow A sodium has sufficient solubility and human tolerance.
    Type: Application
    Filed: June 8, 2013
    Publication date: January 22, 2015
    Applicant: ZHEJIANG YONGNING PHARMACEUTICAL CO LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Patent number: 8168622
    Abstract: ?-lactamase resistant cephalosporin ester compound chosen from those represented by formula (I): wherein, and pharmaceutical salts thereof, composition thereof, and use thereof are disclosed.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: May 1, 2012
    Assignee: Zhejiang Yongning Pharmaceutical Co., Ltd.
    Inventors: Fengqi Ye, Shanzong Fang, Xiuwei Lu