Abstract: A method of reducing biofilm formation on an implant optionally includes soaking an orthopedic or dental implant comprising a biocompatible material in an infection control composition comprising a porphyrin. An implant for implantation in an animal body optionally includes an implant body comprising a biocompatible material and defining one or more reservoirs; and an infection control composition comprising a porphyrin composition configured to be retained in the one or more reservoirs, wherein the one or more reservoirs are configured to elute the porphyrin composition over time.

Abstract: The present disclosure provides for a method of inhibiting the growth of a microorganism including contacting the microorganism with zinc porphyrin (ZnPor). The present disclosure also provides for a method of treating or preventing biofilm formation of one or more microorganisms including contacting the biofilm with zinc porphyrin (ZnPor). Further, the present disclosure provides for a method of treating a disease associated with biofilm formation in a subject including administering to the subject a composition comprising a therapeutically effective amount of ZnPor.