Abstract: The present disclosure provides systems and methods for controlling gas-enrichment, e.g., oxygen-enrichment, therapy. One or more sensors and/or one or more imaging systems may be used to measure or determine one or more physiological parameters of the patient. Feedback regarding one or more physiological parameters or microvascular resistance may be provided for titrating or controlling the gas-enrichment therapy.

Abstract: An intelligent rechargeable battery pack having a battery management system for monitoring and controlling the charging and discharging of the battery pack is described. The battery management system includes a memory for storing data related to the operation of the battery, and the battery management system is also configured to communicate the data related to the operation of the battery to other processors for analysis.

Abstract: In some implementations, data obtained by a temperature management system for delivering temperature management therapy to a patient is presented, within a single display region, as a graph of patient temperature over time representing the timespans of all phases of a multi-phase temperature management therapy. The graph may be fitted to present each phase separately in a manner that retains data complexity. The graph may include power data representing power output over time by a temperature management device. Data from other devices may be incorporated into the graph. A portion of the data may be patient temperature data and/or patient physiological data gathered during a time preceding temperature management therapy by the temperature management device.

Abstract: A working fluid cassette for an intravascular heat exchange catheter includes a frame holding two closely spaced, square polymeric membranes along the sides of which are disposed inlet and outlet tubes. Working fluid from the catheter is directed from the inlet tube between the membranes to the outlet tube. The cassette is closely received between two refrigerant cold plates to exchange heat with the working fluid, which is circulated back to the catheter.

Abstract: A CPR chest compression device with a cooling exhaust flow path configured to direct cooling air flow through the device. A CPR chest compression device with a battery retainer interoperable with the control system to provide for controlled shut-down when an operator attempts to remove the battery during operation.

Abstract: A heat exchange system for exchanging heat with working fluid from an intravascular heat exchange catheter or an external heat exchange pad includes a working fluid that circulates between the catheter or pad and a fluid cassette, and a refrigerant system that flows against the outer sides of cold plates between which the cassette is disposed.

Abstract: The present disclosure provides systems for controlling infusion of one or more supplements into blood received from a patient. The systems include at least one an extracorporeal circulatory support system including a pump, fluid conduits, and at least one a sensor configured to measure one or more parameters of the blood. The system also may include a fluid flow regulator coupled to the extracorporeal circulatory support system. The system receives measurement signals corresponding to parameters of blood from the at least one sensor and determines one or more target values for the parameters of blood based on a patient profile and/or the measurements. The system may control the fluid flow regulator to cause an infusion of at least one supplemental fluid from a supplemental fluid source into the blood.

Abstract: A method of reducing the likelihood of shivering comprises monitoring at least one physiological characteristic in a human or animal subject to detect preshivering and acting to reduce the likelihood of shivering when preshivering is detected.

Abstract: A carrier, such as a battery, that queries a memory of a charger or charging circuit, or the memory of equipment or discharging circuit powered by the battery, to determine the relative date or version of data, operating parameters and/or software on both the battery and the equipment, and either provides updated data, operating parameters and/or software to the equipment, or retrieves later dated data, operating parameters and/or software from the equipment to update the memory of the battery and/or further distribute the updated data, operating parameter sand/or software to other batteries or equipment.

Abstract: A mechanical chest compression device is secured to a gurney, transport stretcher or ambulance cot while engaging a patient's thorax to provide mechanical CPR during transport. The mechanical chest compression device compresses the patient's thorax against the gurney deck. The mechanical chest compression device may engage the side rails on the gurney, the gurney deck or any suitable structural elements of the gurney.

Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.

Abstract: A chest compression device with a chest compression belt assembly including guards and sensors operable with a control system to control operation of the system depending on detection of proper installation of the guards.

Abstract: A chest compression device includes a piston to apply compression to the sternum and incorporates leaf springs simultaneously driven by the piston to apply lateral compression to the thorax during chest compressions. A motor in the chest compression device provides motive power to cyclically extend and contract the piston to provide therapeutic chest compressions. One end of each leaf spring is operably connected to the piston and the other end of each leaf spring is secured to the backboard/base or to a support leg of the chest compression device such that during extension of the piston, each leaf spring is compressed against the device base or leg which causes the springs to flex and provide lateral compression of the patient's thorax in addition to the sternal compression of the piston.

Abstract: A mechanical chest compression device is secured to a gurney, transport stretcher or ambulance cot while engaging a patient's thorax to provide mechanical CPR during transport. The mechanical chest compression device compresses the patient's thorax against the gurney deck. The mechanical chest compression device may engage the side rails on the gurney, the gurney deck or any suitable structural elements of the gurney.

Abstract: A CPR chest compression device with a cooling exhaust flow path configured to direct cooling air flow through the device. A CPR chest compression device with a battery retainer interoperable with the control system to provide for controlled shut-down when an operator attempts to remove the battery during operation.

Abstract: A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.

Abstract: A temperature management system is configured to control a temperature of a patient's body using a heat exchange device. The temperature management system is configured to deliver temperature management treatment or therapy to a patient. A user interface of the system is configured to display operational data and patient data on the user interface in a configuration that allows a user to determine or review one or more periods of the performed temperature management treatment.

Abstract: A system includes a battery pack having an archive, and a portable medical device configured to releasably receive the battery pack. The portable medical device includes a memory and a processor controlled by commands embedded in and/or executed upon the processor and configured to collect, in the memory, operational history data and/or performance data related to the functioning of the portable medical device during use, and load, from the memory to the archive of the battery pack, the operational history data and/or performance data. The battery pack is configured to enable transfer of the operational history data and/or performance data of the portable medical device to a network or server.

Abstract: A closed loop catheter useable for heat exchange is manufactured by forming a plurality of generally transverse bore holes though a flexible, multilumen catheter body, lacing a tube trough the bore holes so that loops of the tube protrude from the catheter body, connecting one end of the tube to an inflow lumen of the catheter and connecting the other end of the tube to an outflow lumen of the catheter. A heated or cooled heat exchange medium may then be circulated through the tube while the catheter is inserted in the vasculature of a subject, thereby resulting in heat exchange between the subject's flowing blood and the heat exchange medium being circulated through the tube.

Abstract: Devices, systems and methods for controlling the temperature of all or part of the body of a human or animal subject.