Abstract: Flavor components, particularly for a vanilla composition, are produced by essentially natural methods employing biotransformation of plant-derived materials. Ferulic acid, a component of many plant cell walls, may be converted into vanillin, directly or indirectly. A plurality of such compounds may undergo bioconversions to produce components of a flavor composition.
Type:
Grant
Filed:
February 24, 2000
Date of Patent:
January 18, 2005
Assignee:
Zylepsis Limited
Inventors:
Peter Samuel James Cheetham, Michelle Lorraine Gradley, John Thomas Sime
Abstract: A method of producing a melanin comprises oxidizing a phenolic compound at one or more hydroxyl groups thereof, wherein the phenolic compound is selected from 5-hydroxyindole and derivatives thereof and compounds of formula (1) and the oxidation is provided by biotransformation in the presence of an oxidoreductase enzyme, the compound of formula (1),
wherein R1 is H or OH; R2 is H, OH orOCH3; R3 is H or OH at least one of R1 and R3 being OH; R4 is selected from H , R, —COOX and R7—COOX, wherein R is an optionally substituted saturated or unsaturated alkyl group having from 1 to 12 carbon atoms, R7 is an optionally substituted saturated or unsaturated alkylene group having from 1 to 12 carbon atoms and X is selected from H and aliphatic and aromatic ester forming groups; and R5 and R6 is each independently selected from H, OH, NH2, OCH3, CH3, SH, NHCO2, NHCH3, COOH and saturated or unsaturated alkyl groups having up to 8 carbon atoms.
Type:
Grant
Filed:
September 25, 1998
Date of Patent:
October 16, 2001
Assignee:
Zylepsis Limited
Inventors:
Nigel E. Banister, Peter S. J. Cheetham
Abstract: The invention relates to methods for treating plant material such as sunflower seed meal with water and a hydrolytic enzyme in an aqueous environment to increase its nutritional value and to enzymatic methods for converting plant derived material into useful products.
Type:
Grant
Filed:
March 31, 1998
Date of Patent:
June 12, 2001
Assignee:
Zylepsis Limited
Inventors:
Stephen John Myers, Peter S.J. Cheetham, Nigel E. Banister
Abstract: There is disclosed a novel method of producing caffeic acid in large quantities, comprising the esterification of chlorogenic acid with an esterifying enzyme. Caffeic acid and its derivatives, produced by this method, may be used in sunscreen compositions, the caffeic acid and its derivatives absorbing both uvA and uvB light.
Type:
Grant
Filed:
March 14, 1997
Date of Patent:
May 23, 2000
Assignee:
Zylepsis Limited
Inventors:
Peter S. J. Cheetham, Nigel E. Banister
Abstract: The invention relates to the use of a sesquiterpene for inhibiting an oxidative enzyme, preferably a cytochrome P450 enzyme. The invention also relates to compositions comprising a sesquiterpene and a drug which exhibits instability in the presence of an oxidative enzyme.
Type:
Grant
Filed:
April 10, 1998
Date of Patent:
April 25, 2000
Assignee:
Zylepsis Limited
Inventors:
John Thomas Sime, Peter Samuel James Cheetham, Michelle Lorraine Gradley, Nigel Eric Banister