Abstract: The present technology relates to a method of treating one or more symptoms of Full Methylation (Fmet) Fragile X Syndrome in a subject that includes administering an effective amount of cannabidiol to the subject such that one or more symptoms of Fragile X Syndrome are treated.
Type:
Application
Filed:
October 9, 2023
Publication date:
April 18, 2024
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
James Griesser, Thomas W. Dobbins, Terri Sebree
Abstract: Described herein are ?9-THC prodrugs, methods of making ?9-THC prodrugs, formulations comprising ?9-THC prodrugs and methods of using ?9-THC. One embodiment described herein relates to the transdermal administration of a ?9-THC prodrug for treating and preventing diseases and/or disorders.
Type:
Application
Filed:
August 1, 2023
Publication date:
March 14, 2024
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Audra Lynn Stinchcomb, Miroslaw Jerzy Golinski, Dana Carmel Hammell, Jeffrey Lynn Howard
Abstract: Provided are methods of treating refractory seizures in a human subject, e.g., a child, that include administering an effective amount of cannabidiol (CBD), e.g., in a transdermal gel.
Type:
Application
Filed:
December 3, 2021
Publication date:
January 11, 2024
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Joseph Palumbo, Donna Gutterman, Terri Sebree
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.
Type:
Application
Filed:
August 30, 2023
Publication date:
December 28, 2023
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Marcel Bonn-Miller, Nancy Tich, Donna Gutterman, John Messenheimer, Terri Sebree
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Autism Spectrum Disorder (ASD) in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of ASD are treated in the subject.
Type:
Application
Filed:
March 21, 2023
Publication date:
November 16, 2023
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Terri Sebree, Marcel Bonn-Miller, Donna Gutterman
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.
Type:
Grant
Filed:
August 24, 2022
Date of Patent:
October 10, 2023
Assignee:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Marcel Bonn-Miller, Nancy Tich, Donna Gutterman, John Messenheimer, Terri Sebree
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of autism spectrum disorder (ASD) in a subject by administering an effective amount of cannabidiol (CBD). Specifically, subjects having moderate to severe ASD and relatively high social avoidance and/or anxiety are more likely to show a reduction in irritability when treated with CBD.
Type:
Application
Filed:
October 20, 2022
Publication date:
February 23, 2023
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Joseph Palumbo, Stephen V. O'Quinn, Terri Sebree, Marcel Bonn-Miller, Donna Gutterman
Abstract: The present technology relates to methods of treating one or more behavioral symptoms (for example, anxiety) of 22q11.2 deletion syndrome in a subject by administering, e.g., transdermally, an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of 22q11.
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.
Type:
Application
Filed:
August 24, 2022
Publication date:
January 5, 2023
Applicants:
ZYNERBA PHARMACEUTICALS, INC., ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Marcel Bonn-Miller, Nancy Tich, Donna Gutterman, John Messenheimer, Terri Sebree
Abstract: The present technology relates to methods of treating one or more behavioral symptoms (for example, anxiety) of 22q11.2 deletion syndrome in a subject by administering, e.g., transdermally, an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral and/or psychiatric symptoms of 22q11.
Abstract: The present technology relates to methods of treating one or more behavioral symptoms (for example, anxiety) of 22q11.2 deletion syndrome in a subject by administering, e.g., transdermally, an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral and/or psychiatric symptoms of 22q11.
Abstract: The present technology relates to methods of treating one or more behavioral symptoms (for example, anxiety) of 22q11.2 deletion syndrome in a subject by administering, e.g., transdermally, an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of 22q11.2 deletion syndrome are treated in the subject.
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.
Type:
Grant
Filed:
August 6, 2020
Date of Patent:
October 4, 2022
Assignee:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Marcel Bonn-Miller, Nancy Tich, Donna Gutterman, John Messenheimer, Terri Sebree
Abstract: The present technology relates to methods of treating behavioral problems and seizures in a subject having developmental and epileptic encephalopathy (DEE) by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein behavioral problems are treated in the subject.
Type:
Application
Filed:
March 17, 2022
Publication date:
July 14, 2022
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Terri Sebree, Donna Gutterman, John Messenheimer
Abstract: Described herein are ?9-THC prodrugs, methods of making ?9-THC prodrugs, formulations comprising ?9-THC prodrugs and methods of using ?9-THC. One embodiment described herein relates to the transdermal administration of a ?9-THC prodrug for treating and preventing diseases and/or disorders.
Type:
Application
Filed:
November 24, 2021
Publication date:
June 23, 2022
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Audra Lynn Stinchcomb, Miroslaw Jerzy Golinski, Dana Carmel Hammell, Jeffrey Lynn Howard
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of Autism Spectrum Disorder (ASD) in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of ASD are treated in the subject.
Type:
Application
Filed:
September 2, 2021
Publication date:
March 31, 2022
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Terri Sebree, Marcel Bonn-Miller, Donna Gutterman
Abstract: The present technology relates to a method of treating one or more symptoms of Full Methylation (Fmet) Fragile X Syndrome in a subject that includes administering an effective amount of cannabidiol to the subject such that one or more symptoms of Fragile X Syndrome are treated.
Type:
Application
Filed:
June 28, 2021
Publication date:
December 30, 2021
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
James Griesser, Thomas W. Dobbins, Terri Sebree
Abstract: The present technology relates to a method of treating one or more behavioral symptoms of autism spectrum disorder (ASD) in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of ASD are treated in the subject.
Type:
Application
Filed:
May 25, 2021
Publication date:
December 2, 2021
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Terri Sebree, Donna Gutterman, Carol O'Neill, Joseph Palumbo
Abstract: The present technology relates to methods of treating SYNGAP1 encephalopathy by transdermally administering an effective amount of cannabidiol (CBD) to the subject, wherein a SYNGAP1 symptom is treated in the subject.
Type:
Application
Filed:
September 16, 2020
Publication date:
March 18, 2021
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Terri Sebree, John Messenheimer, Donna Gutterman
Abstract: Described herein are ?9-THC prodrugs, methods of making ?9-THC prodrugs, formulations comprising ?9-THC prodrugs and methods of using ?9-THC. One embodiment described herein relates to the transdermal administration of a ?9-THC prodrug for treating and preventing diseases and/or disorders.
Type:
Application
Filed:
August 28, 2020
Publication date:
February 18, 2021
Applicant:
ZYNERBA PHARMACEUTICALS, INC.
Inventors:
Audra Lynn Stinchcomb, Miroslaw Jerzy Golinski, Dana Carmel Hammell, Jeffrey Lynn Howard