Patents Assigned to Zyngenia, Inc.
  • EGFR-binding modular recognition domains
    Patent number: 10150800
    Abstract: EGFR-binding modular recognition domains (MRDs) and complexes containing such MRDs linked to antibodies are described. The use of such MRDs and complexes are also described.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 11, 2018
    Assignee: Zyngenia, Inc.
    Inventors: Viktor Roschke, David Lafleur, David M. Hilbert, Peter Kiener
  • Polynucleotides encoding angiopoietin-2 (ang-2) binding polypeptides
    Patent number: 10087222
    Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 2, 2018
    Assignee: Zyngenia, Inc.
    Inventors: Viktor Roschke, David Lafleur, David M. Hilbert, Peter Kiener
  • Ang-2-binding modular recognition domain complexes and pharmaceutical compositions thereof
    Patent number: 9676833
    Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: June 13, 2017
    Assignee: Zyngenia, Inc.
    Inventors: Viktor Roschke, David Lafleur, David M. Hilbert, Peter Kiener
  • Multivalent and Monovalent Multispecific Complexes and Their Uses
    Publication number: 20150210765
    Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.
    Type: Application
    Filed: September 9, 2014
    Publication date: July 30, 2015
    Applicant: ZYNGENIA, INC.
    Inventors: VIKTOR ROSCHKE, DAVID LAFLEUR, DAVID M. HILBERT, PETER KIENER
  • Monovalent and Multivalent Multispecific Complexes and Uses Thereof
    Publication number: 20140088019
    Abstract: Monovalent and multivalent multispecific complexes including ELP-MRD fusion proteins containing one or more modular recognition domains (MRDs) that bind target antigens are described. The use of these monovalent and multivalent multispecific complexes (e.g., ELP-MRD fusion proteins) in diagnostic, prognostic, and therapeutic applications and methods of making these complexes are also described.
    Type: Application
    Filed: February 10, 2012
    Publication date: March 27, 2014
    Applicant: Zyngenia, Inc.
    Inventor: David M. Hilbert
  • Multivalent and Monovalent Multispecific Complexes and Their Uses
    Publication number: 20140065142
    Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Applicant: Zyngenia, Inc.
    Inventors: Viktor ROSCHKE, David Lafleur, David M. Hilbert, Peter Kiener
  • Monovalent and Multivalent Multispecific Complexes and Uses Thereof
    Publication number: 20120213781
    Abstract: Monovalent and multivalent multispecific complexes including ELP-MRD fusion proteins containing one or more modular recognition domains (MRDs) that bind target antigens are described. The use of these monovalent and multivalent multispecific complexes (e.g., ELP-MRD fusion proteins) in diagnostic, prognostic, and therapeutic applications and methods of making these complexes are also described.
    Type: Application
    Filed: February 10, 2012
    Publication date: August 23, 2012
    Applicant: Zyngenia, Inc.
    Inventor: David HILBERT
  • Ang-2 Binding Complexes and Uses Thereof
    Publication number: 20120100166
    Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.
    Type: Application
    Filed: July 15, 2011
    Publication date: April 26, 2012
    Applicant: Zyngenia, Inc.
    Inventors: Viktor Roschke, David Lafleur, David M. Hilbert, Peter Kiener