Abstract: Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.
Type:
Grant
Filed:
June 19, 1998
Date of Patent:
April 18, 2000
Assignee:
Peptor Limited
Inventors:
Vered Hornik, Gary Gellerman, Mich El M Afargan
Abstract: A new cyclic heptapeptide, trunkamide A, with antitumor activity has been isolated from a Lissoclinium sp. collected on the Great Barrier Reef, Australia.
Type:
Grant
Filed:
February 19, 1999
Date of Patent:
February 15, 2000
Assignee:
Pharma Mar, s.a.
Inventors:
Bruce Frederick Bowden, Dolores Garcia Gravalos
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