Abstract: Embodiments of the present invention provide solid oral dosage forms that upon daily administration to a subject provide plasma levels of decitabine with a 5-day AUC for decitabine that is equivalent to the 5-day AUC for a daily IV dose of decitabine of 20 mg/m2 administered as a one hour (1 h) infusion. Also provided according to embodiments of the present invention are solid oral dosage forms wherein upon daily administration to a subject provides a pharmacodynamic effect that is equivalent to the pharmacodynamic effect for a daily intravenous dose of decitabine of 20 mg/m2 administered as a one hour (1 h) infusion. Also provided are methods of treatment using a solid oral dosage form according to an embodiment of the invention.
Type:
Grant
Filed:
April 28, 2023
Date of Patent:
April 23, 2024
Assignee:
Otsuka Pharmaceutical Co., Ltd.
Inventors:
Aram Oganesian, Nipun Davar, Jim Hwaicher Kou
Abstract: An organic electroluminescence device includes an anode, an emitting layer and a cathode, in which the emitting layer includes a first compound, a second compound and a third compound. The first compound is a compound represented by a formula (1) below. The second compound has a larger singlet energy than a singlet energy of the first compound. The third compound is a fluorescent compound.
Abstract: A video coding mechanism is disclosed. The mechanism includes receiving an extracted bitstream that is a result of a sub-bitstream extraction process from an input bitstream containing a set of sub-pictures. The extracted bitstream contains only a subset of the sub-pictures of the input bitstream to the sub-bitstream extraction process. A flag from the extracted bitstream is set to indicate that sub-picture information related to the subset of the sub-pictures is present in the extracted bitstream. One or more sub-picture identifiers (IDs) for the subset of the sub-pictures are obtained based on the flag. The subset of the sub-pictures is decoded based on the sub-picture IDs.
Abstract: An electronic apparatus includes an organic light-emitting device including: a first electrode, a second electrode facing the first electrode, m light-emitting units stacked between the first electrode and the second electrode and including at least one emission layer; and m?1 charge generating layers, each located between two neighboring light-emitting units of the m light-emitting units and including an n-type charge generating layer and a p-type charge generation layer, wherein m is an integer of 2 or more, at least one of the m?1 p-type charge generation layers includes a first doping layer and a second doping layer, the first doping layer includes a first organic material and a first inorganic material, the second doping layer includes a second organic material and a second inorganic material, and the first inorganic material and the second inorganic material are different from each other.
Type:
Grant
Filed:
January 12, 2021
Date of Patent:
April 23, 2024
Assignee:
Samsung Display Co., Ltd.
Inventors:
Jaeweon Hur, Seulong Kim, Hyeongpil Kim, Sungsoo Bae, Dongchan Lee
Abstract: A method for encoding a volumetric video content representative of a 3D scene is disclosed. The method comprises obtaining a reference viewing box and an intermediate viewing box defined within the 3D scene. For the reference viewing bounding box, the volumetric video reference subcontent is encoded as a central image and peripheral patches for parallax. For the intermediate viewing bounding box, the volumetric video intermediate sub-content is encoded as intermediate central patches which are differences between the intermediate central image and the reference central image.
Type:
Grant
Filed:
November 30, 2020
Date of Patent:
April 23, 2024
Assignee:
InterDigital VC Holdings, Inc.
Inventors:
Charles Salmon-Legagneur, Bertrand Chupeau, Julien Fleureau
Abstract: A first dynamic flash memory cell formed on a first Si pillar 25a including an N+ layer 21a, a P layer 22a, and an N+ layer 21b, and a second dynamic flash memory cell formed on a second Si pillar 25b including a P layer 22b and an N+ layer 21c, the first dynamic flash memory cell and the second dynamic flash memory cell sharing the N+ layer 21b that is connected to a first bit line BL1, are stacked on top of one another on a P-layer substrate 20 to form a dynamic flash memory. In plan view, a first plate line PL1, a first word line WL1, a second word line WL2, and a second plate line PL2 extend in the same direction and are formed to be perpendicular to a direction in which the first bit line BL1 extends.