Abstract: There is provided a satiety inducing food product including Agar and Alginate particles having a size range of about 0.5-30 mm, wherein the particles are configured to remain essentially intact in the stomach and in the intestine so as to occupy volume within the stomach and the intestine and thereby induce satiety.

Abstract: Methods for improving solubility of active pharmaceutical ingredients (APIs) through co-attriting the APIs with select excipients, especially solubility enhancing excipients, and the products prepared by the methods, are disclosed. Pharmaceutical compositions containing co-attrited mixture of an API with a solubility enhancing excipient and use of the pharmaceutical compositions for treatment of diseases or disorders are also disclosed.

Abstract: The present invention relates to an injectable pharmaceutical composition containing a prodrug of caspase inhibitors, and a preparation method therefor. More specifically, the present invention relates to an injectable pharmaceutical composition, and a preparation method therefor, the composition comprising, as an active ingredient, (2S,3S)-2-(fluoromethyl)-3-((R)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamido)-5-oxotetrahydrofuran-2-yl acetate, which is a prodrug of caspase inhibitors, or a pharmaceutically acceptable salt or isomer thereof, and comprising, as a biocompatible polymer, microspheres containing poly(lactide-co-glycolide).

Abstract: A cosmetic composition includes a firming system that includes: a pectin; at least one powder; water; at least one fatty compound; and at least one plasticizer. The firming system when is spreadable and wherein upon drying the firming system forms a firming film that exhibits cohesion and adhesion when applied to a substrate. The pectin may comprise low methoxyl pectin, and the firming system may further include at least one monosaccharide, disaccharide or combination thereof. The composition may include a cosmetic carrier system wherein the firming system and cosmetic carrier system is in the form of liquidous or creamy type emulsion or an oil free serum for application to skin to ameliorate the signs of aging or a viscous liquidous emulsion or suspension for application as a makeup to keratinous tissue selected from skin, lashes and hair to confer firming to the keratinous tissue.

Abstract: The present invention relates to a process for the preparation of microcapsules, in particular isocyanate-based microcapsules with improved stability to carboxylic acid and aldehyde-containing active ingredients as core material. In addition, the present invention relates to microcapsules obtainable by the process according to the invention. In addition, the present invention relates to microcapsules, suspensions of such microcapsules, and the use of the microcapsules and suspensions as a component in detergents, fabric softeners, cleaning products, scent boosters (fragrance enhancers) in liquid or solid form, cosmetics, personal care products, agricultural products, or pharmaceutical products.

Abstract: Embodiments of vesicles comprising embedded cytotoxic agents are disclosed, as well as methods of making and using the vesicles. Pharmaceutical compositions including the vesicles also are disclosed. The vesicles include a binary lipid bilayer surrounding a cavity, wherein the vesicle binary lipid bilayer includes (i) a non-bilayer forming lipid (or combination of non-bilayer forming lipids) and a PEGylated lipid; and (i) a cytotoxic agent embedded within the vesicle wall.

Abstract: A metformin tablet, a metformin tablet for relieving pain and reducing inflammation, and a manufacturing method thereof. The tablet for relieving pain and reducing inflammation comprises: a filler, a diluent, an excipient, a binder, a slow-release agent, a sweetener, and a medicinal powder; the excipient comprises: at least one of PVP, PEG, and polymer; the medicinal powder comprises: at least one of metformin and the excipient. The metformin tablet comprises: a hollow part, a thick colloidal layer formed on an outer side of the hollow part, and a powder colloidal layer formed on an outer side of the thick colloidal layer. The tablet for relieving pain and reducing inflammation comprises: a thick colloidal layer, a powder colloidal layer formed on an outer side of the thick colloidal layer, and a hollow part located at a center of the tablet and on an inner side of the thick colloidal layer.

Abstract: The present invention relates to a process for spray drying of a feed solution comprising semaglutide, said process comprising introducing the feed solution comprising semaglutide in a solvent into a spray dryer and introducing an atomising gas and a drying gas, characterised in that the spray dryer comprises a gas heater for the drying gas with an inner surface comprising iron and less than 18.5% chromium.

Abstract: A hybrid composition of partially pre-gelatinized cassava starch powder is herein disclosed. The hybrid composition is obtained by a pre-compaction process and a wet-granulation process, and the partially pre-gelatinized cassava starch including birefringent portions and non-birefringent portions. The hybrid composition is formulated for use in, for example, tablets, and may be used as a multi-functional excipient in various powder formulations.

Abstract: A translucent hair care composition comprising a substituted 2-pyridinol-N-oxide material, a cationic surfactant, a fatty alcohol, a water-soluble polymer, water, and a monocarboxylic acid.

Abstract: The present disclosure relates to hair styling compositions that exhibit non-Newtonian shear thinning behavior during use. The hair styling composition include: (a) one or more fatty amides, fatty alkanolamides, and/or alkoxylated fatty amides; (b) one or more non-hydroxy substituted fatty acids; (c) one or more hydroxy substituted fatty acids; (d) at least 70 wt. % of one or more low-polar oils; and less than 2 wt. % of water. Additional components such as, for example, alkoxylated polyol esters, water-soluble organic solvents, and other miscellaneous ingredients, can optionally be included in the hair styling compositions. The hair styling compositions are particularly useful for styling or shaping hair and for providing hold, discipline, and texture to hair.

Abstract: A method for reducing the appearance of post-acne marks, lightening dark spots and discoloration, fading post-acne marks faster and/or preventing appearance of new post-acne marks by applying a skin care composition. The skin care composition contains a vitamin B3 compound, hydroxycinnamic acid, and water at a pH of less than 5.0.

Abstract: Hair care compositions and methods for using the same are disclosed herein. According to one aspect of the disclosure, a hair care composition is provided that includes from about 1 to about 20 wt. % of an anionic surfactant; from about 0.5 to about 5 wt. % of an amphoteric surfactant; from about 0.1 to about 7 wt. % of a nonionic surfactant; from about 0.1 to about 5 wt. % of a thickening agent, wherein the thickening agent is a natural gum; and from about 0.05 to about 4.5 wt. % of a silicone wherein the hair composition is an emulsion and all weight percentages are based on the total weight of the hair care composition. Additionally, the hair care composition may have a weight ratio for the total amount of anionic surfactant to the total amount of amphoteric surfactant that is about 5:1 to about 20:1.

Abstract: The invention provides a making method of modified polyvinyl alcohol embolic microspheres. First, polyvinyl alcohol dimethyl sulfoxide solution is added to acryloyl chloride dichloromethane solution for reaction, then taurine solution is added to the above solution for further reaction, so that functional groups are introduced into the side chains of polyvinyl alcohol, then blank microspheres are prepared by suspension crosslinking method, and finally, drug-loaded modified polyvinyl alcohol embolic microspheres are prepared. The invention aims at improving the drug loading rate and drug loading speed of the microspheres. Through modification, the crystallinity of polyvinyl alcohol is weakened, the swelling in water is accelerated, and the application effect of the microspheres is improved.