Abstract: A method for calculating blood oxygen saturation includes defining the extreme value point of a non-red light signal as the extreme value point of a red light signal, and calculating the blood oxygen saturation according to the extreme value point of the red light signal. The method for calculating blood oxygen saturation of the present disclosure proposes to use other light source signals to assist in finding the period of the red light signal, so that the calculation result of the red light signal is more accurate.

Abstract: A device for the continuous and real-time monitoring of bilirubin, comprises a housing that encloses a waterproof/splash proof body. The body comprises a bilirubin and temperature measuring module; a wearable biocompatible strap; a buckle; a display unit; a safety module; a learning module; a battery and charging unit; a switch; and a wireless connectivity facilitator. The bilirubin and temperature measuring module comprises: one or more light emitting sources; a microprocessor; one or more photodetectors; a filter; and an analogue to digital converter. The device can be configured to be mounted on a patient's wrist or any other body part like palm, earlobe, cheek, finger, forehead, and feet.

Abstract: A sensor (220) for a body monitoring system (1), having analyte-measuring microneedles (210) that extend parallel to a main direction (Z) from a substrate (242) and define a working plane (Pt), wherein the sensor (220) has at least one conductivity electrode (600) with a metallic track (602), the end of the metallic track extending along the main direction (Z) to a position strictly between the substrate (242) and the working plane (Pt).

Abstract: An integrated window for a photosensor for use in an electronic device has first and second transparent regions separated by an opaque region. The first transparent region allows a transmitter to emit light out of the housing of the electronic device and the second transparent region allows a receiver to receive light through the housing. The opaque region is disposed between the first and second transparent regions to isolate them from one another such that the transmitted light is isolated from the received light.

Abstract: A method for automatically assessing information processing speed in a test subject is disclosed. In the inventive method, a first qualimetric activity parameter for sensorial transmission, cognition and motoric output activity is determined and a second qualimetric activity parameter for sensorial transmission and motoric output activity is determined. A third qualimetric activity parameter for cognition is determined by comparing the first and the second qualimetric activity parameters to each other, and the information processing speed in the test subject is assessed based on the first, second and third qualimetric activity parameters. The information processing speed can be determined by comparing the determined qualimetric activity parameters to a reference and the subject's cognitive impairment can then be determined from the processing speed. The inventive method can be computer implemented. A mobile device or system for carrying out the disclosed methods is also disclosed.

Abstract: A biosensor system has a capsule with a housing configured for ingesting in a mammal GI tract, being cylindrical with domed ends. The housing forms an external space akin to a “cut-out” shape with two opposing transparent walls facing each other in the longitudinal direction and a base wall facing radially. An LED emitter emits at a number of wavelengths in time sequence, and radiation is detected by a photo-detector via the wall which forms a concave lens. An antenna is for wireless transmission of data to an external device and is in the form of conical spiral in an overall conical shape, located for optimum space efficiency in a domed end. A battery compartment is at the opposed end of the housing, separated from the antenna by the external space.

Abstract: An optical data sensing device of a biological information measuring device, comprising: an optical sensor; a first light emitting device, configured to emit first light away from the optical sensor; and a first opaque isolation component, located between the optical sensor and the first light emitting device, configured to reduce the first light received by the optical sensor. The present invention also discloses an optical data sensing device comprising a plurality of light emitting devices with different emitting directions or wavelengths, to improve the accuracy of biological information measuring.

Abstract: Systems, methods, and apparatuses for enabling non-invasive, physiological sensors to obtain physiological measurements from a region of tissue of a patient are disclosed. Anchoring components can attach to patient tissue sites and sensor heads such that the tissue sites do not move during sensing. Interlocking mechanisms maintain tissue sites within a limited range of horizontal movement and vertical distance from the sensor head.

Abstract: The present disclosure provides a calibration system and method for calibrating a physiological measurement based on a variable that affects the measurement. The variable can be a related physiological measurement. The technique can be implemented to obtain robust calibrations with minimal test data and computational effort.

Abstract: Systems and methods are described, and one method includes determining a fetal blood oxygenation level, including: activating at least one light source with at least two distinct wavelengths of light on an abdomen of a pregnant mammal to direct light into a maternal abdomen toward a fetus; receiving a set of mixed signals from a set of photodetectors positioned at different locations on the maternal abdomen from reflected light that traverses maternal tissue or maternal tissue and fetal tissue; determining the fetal blood oxygenation level by performing computations on a composite fetal signal produced from the mixed signals; and ensuring a skin temperature of the maternal abdomen does not rise to unsafe levels due to activating the at least one light source.

Abstract: A measurement system and method of manufacture can include: a pressure resistant structure; a pressure inducer coupled to the pressure resistant structure, the pressure inducer having an engaged configuration, the engaged configuration of the pressure inducer increasing pressure exerted on a portion of a user in contact with the pressure resistant structure; a light source coupled to the pressure resistant structure; an optical sensor coupled to the pressure resistant structure and configured to detect a signal from the light source; a pressure sensor coupled to the pressure resistant structure, the pressure sensor configured to detect the pressure exerted on the portion of the user in contact with the pressure inducer; and a processor coupled to the optical sensor and the pressure sensor, the processor configured to correlate volumetric data from the optical sensor with pressure data from the pressure sensor and to provide a blood pressure measurement.

Abstract: A wearable device includes a housing; a wrist band attached to the housing; first and second emitters positioned within the housing and configured to respectively emit, through a back of the housing, a first beam of electromagnetic radiation having a first infrared (IR) wavelength and a second beam of electromagnetic radiation having a second IR wavelength. The second IR wavelength is different from the first IR wavelength. The wearable device also includes a photodetector positioned within the housing and filtered to detect a set of electromagnetic radiation wavelengths including the first IR wavelength and the second IR wavelength; and a matter differentiation circuit configured to indicate, at least partly in response to signals indicating amounts of the first IR wavelength and the second IR wavelength received by the photodetector, whether the back of the housing is likely proximate to human tissue.

Abstract: An apparatus for analyzing a biological material component may include an impedance sensor comprising a first electrode having a first contact surface that contacts an analysis target, and a second electrode having a second contact surface that contacts the analysis target and that faces the first contact surface. The apparatus may include an impedance measurement assembly configured to measure impedance of the analysis target using the first electrode and the second electrode. The apparatus may include a processor configured to model the measured impedance as an equivalent circuit, and analyze a biological material component based on a modeling result.

Abstract: A wearable module for use in an optical measurement system includes a light guide configured to receive a light pulse from a light source and guide signal photons included in the light pulse toward a target within a body of a user, and a light diverter configured to divert reference photons included in the light pulse toward at least one detector configured to detect the reference photons.

Abstract: An assembly having a patch (250) for a body-monitoring system, the patch having a main body (251) with an opening (252) of at least 2 mm diameter, the main body having a rigid zone (256) around the opening and a flexible zone (258) on either side of the rigid zone and preferably all around the rigid zone, and a capsule (220), the capsule being configured to be placed in the opening of the patch and to be rigidly attached to same. The capsule has microneedles (210) configured to be inserted in the skin in order to sample or analyse a bodily fluid of the wearer of a body-monitoring system when the system is positioned on a limb of a user, the rigid zone of the capsule enabling a transmission of the forces received by the patch to the capsule.

Abstract: A sensor device includes a housing defining a cavity, an inlet to receive fluid pumped from an instrument device, an outlet to return the fluid to a fluid reservoir, and a fluid channel defined inside the cavity between the inlet and the outlet. A heat pump is mounted inside the cavity, and has a side surface thermally coupled to the fluid channel and an opposite side surface thermally coupled to a plate. The heat pump is configured to induce a temperature change. A sensor unit is aligned with an aperture in the plate and includes an optical component and a thermal component. The optical component configured to measure a vascular endothelial response from the induced temperature change.

Abstract: An electronic device includes a light source, a light sensor, and a controller that senses an amount of a coarse ambient light by turning off the light source and performing sensing in a coarse mode by using the light sensor and senses an amount of a fine ambient light by performing sensing in a fine mode by using the light sensor. The controller senses an amount of a target light by turning on the light source and performing sensing by using the light sensor while the light source emits a light, and outputs information based on the amount of the coarse ambient light, the amount of the fine ambient light, and the amount of the target light.

Abstract: Various sensor tapes can improve securing of a non-invasive optical sensor to a surface of a medium for taking noninvasive measurement of characteristics of the medium. The sensor tape can taper from a wide end to a narrow end. The sensor tape can transition from a wide portion to a narrow portion in a step-like change or slope. The sensor tape can have staggered portions. The various tapes can be used with an L-shaped sensor. The various tapes can increase contact surface between the surface of the medium and an adhesive side of the tape so as to reduce motion-induced noise.

Abstract: The accuracy of physiological data measured through contact with skin can be validated by characterizing the forces at the surfaces where data is measured. Conventional devices do not monitor the fit of skin-based sensors, making the accuracy and confidence in physiological data dependent on the user ensuring that the device is fitted properly. Over time, the seating of a device will vary due to changes in user activity and the need to periodically remove a device. Inevitably, instances will arise where the device is not fitted correctly, which may result in skewed physiological metrics. By monitoring the forces acting on the housing of a device, the interface of skin sensors can be characterized allowing for confidence metrics in the corresponding physiological data to be determined. In some cases, a user can be notified when a device is not seated properly, and in some cases, data may even be calibrated based on the fit of a device.

Abstract: A body-monitoring system (1), intended to be attached to a limb of a living being, having a first module (100) having fastening and clamping mechanisms (110) configured to hold and clamp the system (1) on a limb; a second module (200) having microneedles (210) configured to be inserted into the skin in order to sample and/or analyse a bodily fluid of the wearer of the body-monitoring system (1) when positioned on the limb, the two modules (100, 200) being able to be coupled together in position by a complementarity of shape. The first module (100) and the second module (200) are connected together by a separable link (300), the separable link being configured to be released when a tearing threshold is exceeded, the link also being reusable.