Abstract: The present invention pertains to a swallowable electrochemical sensor, which is characterized in that its housing has electrolyte inlets, through which an aqueous electrolyte, for example, gastric acid, can enter from the area surrounding the sensor into the interior and act as an electrolyte there.

Abstract: Devices, systems and methods are provided for delivering pulsed electric field (PEF) energy to tissue through one or more energy delivery bodies, each having one or more electrodes. The PEF energy is generated from a waveform having a variety of features. Waveform delays, such as inter-pulse delays, inter-cycle delays, inter-phase delays, inter-packet delays, inter-bundle delays, may be utilized within a treatment to obtain a desired outcome. In particular, these delays may be specifically manipulated to obtain particular desired outcomes. For example, one, some or all of these delays may be manipulated to control various aspects of PEF therapy so as to mitigate any associated risks, such as gas formation, electrical discharge, cavity formation, muscle contraction, and temperature rise, to name a few. In some embodiments, the delays distribute the period over which PEF energy is delivered, resulting in marked changes and optimization to the treatment delivery outcomes.

Abstract: Apparatus for measuring a torque, consisting of a probe having a shaft with a shaft distal end. The probe has a distal end assembly, configured to be inserted into an organ of a human subject, and having a distal termination and a proximal termination connected to the shaft distal end. A position sensor assembly is attached to the distal end assembly in proximity to the distal termination, the position sensor assembly being configured to provide signals indicative of a three-dimensional position and orientation of the distal termination with respect to the shaft distal end. A processor is configured to compute a torsion of the distal termination with respect to the proximal termination in response to the signals from the position sensor assembly, and compute the torque on the distal end assembly in response to the torsion and a predetermined correspondence between the torsion and the torque.

Abstract: Described herein are examples of a left atrial appendage (“LAA”) occlusion or elimination implant device further configured to ablate tissue located at an atrium of the heart or nearby veins and ostia. The implant device can be delivered to a patient's heart using a catheter system and includes a contact member comprising one or more electrodes. In use, the electrodes of the contact member can perform unipolar or bipolar ablation at an ablation site that is distinct from an ostium or interior of the LAA. The implant device can then be re-positioned at least partially within the LAA, and the contact member can be implanted to occlude or eliminate the LAA. The implant device can further include a securing element comprising one or more electrodes, the securing element configured to cooperate with the contact member in performing unipolar or bipolar ablation and/or occluding or eliminating the LAA.

Abstract: The disclosed technology includes basket catheters comprising a generally cylindrical structure having electrodes attached thereto. The disclosed technology can include a structural unit for an end effector comprising a proximal member extending along a longitudinal axis. The proximal member can define a plurality of divergent curvilinear members. Each divergent curvilinear member can define two meander members extending along the longitudinal axis such that the structural unit comprises a plurality of meander members. Each of the plurality of meander members can be connected to a respective convergent curvilinear member of a plurality of convergent curvilinear members. The structural unit can further comprise a distal member connected to the plurality of convergent curvilinear members.

Abstract: Computer system is configured to receive electrocardiogram signal, from electrocardiographic sensor, configured to indicate cardiac cycle of heart of patient. Computer system is also configured to generate electrocardiogram tracing based on electrocardiogram signal that was received. Computer system is also configured to identify treatment time duration is configured to span a part of electrocardiogram tracing that was generated, and tissue layer is treatable during, at least in part, treatment time duration. This is done in such a way that, during treatment time duration, blood pressure within heart urges tissue layer to impart relatively lower amount of tissue force toward treatment device while treatment device is positioned proximate to tissue layer, and treatment device is activated to treat the tissue layer. The computer system is also configured to provide treatment time duration that was identified.

Abstract: A medical device that includes a handle, a sheath extending from the handle, and a tool within the sheath and movable relative to the sheath. The handle includes an inner body and an outer body disposed over the inner body. The outer body is movable relative to the inner body. The handle includes a first actuator secured to the tool. The first actuator has an actuated state permitting movement of the tool relative to the sheath in response to moving the outer body relative to the inner body. The handle includes a second actuator secured to the sheath. The second actuator has an actuated state permitting movement of the sheath relative to the tool in response to moving the second actuator relative to the outer body. An unactuated state of the first actuator and an unactuated state of the second actuator prevents movement of the tool relative to the sheath.

Abstract: An apparatus includes a body, a catheter, and an end effector. The catheter extends distally from the body and includes a lumen. The end effector includes at least one electrode. The end effector further includes at least one port in fluid communication with the lumen of the catheter such that the lumen is operable to communicate the fluid from a fluid source to the at least one port. The end effector further includes at least one flexible sleeve positioned over the at least one port, the at least one flexible sleeve being configured to transition between a closed state in which the at least one flexible sleeve prevents the fluid from exiting the at least one port, and an open state in which the at least one flexible sleeve permits the fluid to exit the at least one port.

Abstract: The present application refers to a process and a system for collecting, storing, analyzing and visualizing electrocardiographic (ECG) data collected by portable ECG device (100) with embedded wireless communication technology, additionally containing a portable ECG device (100), a hermetically sealed box (200) of medicines containing a lock system comprising a lock (220), a first device (310) to be accessed by the patient, a second device (320) to be accessed by the medical professional, a platform for graphical display of ECG data, and a remote data storage and processing central. The hardware board of the portable ECG device contains wireless communication technology, global positioning system (GPS), start button (141), rechargeable battery charging port, and an equipment configuration and programming port. The battery (120) is Li-Ion type, containing LEDs indicating device operation, and waiting for connection. The battery status is displayed on the app display.

Abstract: The disclosed technology includes a medical probe comprising a tubular shaft having a proximal end and a distal end, the tubular shaft extending along a longitudinal axis. The medical probe further comprises an expandable basket assembly coupled to the distal end of the tubular shaft. The basket assembly includes a plurality of electrodes with each electrode of the plurality of electrodes having a lumen therethrough. The basket assembly further includes a plurality of spines extending along the longitudinal axis and configured to bow radially outward from the longitudinal axis when the expandable basket assembly is transitioned from a collapsed form to an expanded form. Each spine includes a proximal and a distal end and a strut passing through the lumen of an electrode. The strut includes a mechanical retainer disposed on the strut to prevent the electrode from sliding proximally or distally along a length of the spine.

Abstract: Embodiments described herein relate to magnetically steerable irrigated ablation catheters and methods of operating the same. A steerable catheter can include a distal tip including a first set of magnets. The steerable catheter further includes a shaft. The shaft includes a flexible section with a distal end coupled to the distal tip. The shaft further includes a second set of magnets spaced along a length of the flexible section and spaced from the first set of magnets such that the first and second sets of magnets collectively enable the flexible section to curve without kinking in response to a magnetic field being applied to the first and second set of magnets. In some embodiments, each magnet from the second set of magnets can be coupled to the flexible section via metallic elements disposed at the ends of each magnet.

Abstract: The present invention relates to a tube member having excellent local bending properties that is capable of being freely bent only on a given region thereof at a working temperature, thereby enabling the bending angle thereof to be freely adjusted by a user, and a method for manufacturing the tube member. According to the present invention, the tube member having excellent local bending properties, which is made of an alloy, may include a first region and a second region having different alloy structures from each other. According to the present invention, the first region may be in a cold-worked state or have an austenite phase at a given working temperature, and the second region may have a martensite phase at the given working temperature and a yield stress value lower than a yield stress value of the first region.

Abstract: In one embodiment, a catheter alignment system includes a catheter to be inserted into a body part, and including catheter electrodes to contact tissue at respective locations within the body part, a display, and processing circuitry to receive signals provided by the catheter, assess respective levels of contact of ones of the catheter electrodes with the tissue of the body part responsively to the received signals, find a direction in which the catheter should be moved to improve at least one of the respective levels of contact of at least one of the catheter electrodes responsively to the respective levels of contact of the ones of the catheter electrodes, and render to the display a representation of the catheter responsively to the received signals, and a direction indicator indicating the direction in which the catheter should be moved responsively to the found direction.

Abstract: The disclosed technology includes an expandable basket assembly for a medical probe, which may include a single unitary structure comprising a plurality of spines converging at a central spine intersection, the central spine intersection being positioned on a longitudinal axis of the expandable basket assembly at a distal end thereof. The plurality of spines may include a first layer and a second layer attached to the first layer and including a central cutout about the central spine intersection that exposes the first layer at the central spine intersection. The plurality of spine may include a central electrode attached to the first layer at the central spine intersection via a central aperture in the first layer at the central spine intersection. The second layer may be configured to articulate independently of the first layer at the central spine intersection.

Abstract: A catheter including: an elongated body sized to traverse vasculature; a lumen formed in the elongated body; and a pull-wire. The elongated body has a transition zone disposed between proximal and distal ends of the elongated body, a first shaft extending from the proximal end of the elongated body to the transition zone and defining a longitudinal axis, and a second shaft extending proximally from the distal end to the transition zone. The lumen defines a curved path curved about the longitudinal axis and extending from the distal end to the transition zone, and a straight path extending from the transition zone to the proximal end. The pull wire extends within the curved and straight paths, and is anchored to the second shaft such that translation of the pull-wire near the proximal end deflects the second shaft substantially along the curved path.

Abstract: A modular catheter system includes a guiding sheath and multiple catheter inserts configured to couple to the guiding sheath. The guiding sheath can include a navigation sensor coupled to a distal portion of the guiding sheath shaft. A location of a distal portion of a respective catheter insert can be determined based on electrical signals from the navigation sensor. The catheter insert can be electrically coupled to the guiding sheath to provide electrical connection to an electrode assembly on the distal portion of the respective catheter insert. The guiding sheath may include a deflection mechanism that deflects the distal portion of the guiding sheath and a distal portion of a catheter shaft of the catheter insert. The modular catheter system may be configured to be tracked and moved without the catheter inserts requiring a navigation sensor or a deflection mechanism.

Abstract: A system includes a catheter and a processor. The catheter includes (i) a shaft for insertion into a cavity of an organ of a patient, (ii) an expandable distal-end assembly coupled to a distal end of the shaft and comprising splines fitted with spline-electrodes, (iii) a proximal position sensor and a respective proximate proximal electrode located both at a proximal end of the distal-end assembly, and (iv) an independent wire that extends at the distal tip, with a distal position sensor and a respective proximate distal electrode located both at a distal end of the independent wire. The processor is configured to estimate locations of one or more of the spline-electrodes by performing impedance measurements on the one or more of the electrodes, and to calibrate the impedance measurements based on signals received from the proximal position sensor and the distal position sensor and the respective proximal and distal electrodes.

Abstract: Technical improvements in the field of electromedical devices, in particular of electromedical electrodes and/or electromedical catheters are provided. As an improvement, inter alia, a base element (1) for an electromedical device (2) is proposed, which includes, on a carrier element (3), at least one sensor module (4), at least one processing module (5), and at least one data line (6), to which the at least one processing module (5) of the base element (1) is connected. An electromedical device (2) can then be configured as needed from at least one base element (1) or preferably from multiple base elements (1).

Abstract: The biometric and performance monitoring system includes a computer having a mouse and a keyboard electronically coupled thereto. A first sensor is disposed in the mouse, and is electrically coupled to the computer. A second sensor is disposed in the keyboard and is electrically coupled to the computer. The first sensor and the second sensor measure biometric parameters of a user. A computer-readable storage medium is associated with the computer and is adapted for storing the biometric parameters and the performance parameters. The computer measures performance parameters associated with the mouse and with the keyboard. The computer at least one of provides an alert to the user, electronically communicates with a medical service provider, and electronically communicates with a supervising entity responsive to analysis of changes in the biometric parameters and the performance parameters.

Abstract: Devices, systems, and methods for therapeutically treating tissue. The devices and methods are suitable for minimally invasive surgery or open surgical procedures. More particularly, methods and devices described herein permit accessing and/or treating areas of tissue with a therapeutic device.