Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject.

Abstract: Parameters related to use of a prosthesis by a patient with a limb amputation are monitored using a tool that includes one or more piezoelectric force sensors. The resulting data are processed for use both in short and long term management of amputee patients. The sensor is a small modular unit that fits within or between traditional prosthetic components, e.g., below a prosthesis socket. The data produced by the tool are collected, processed, and stored. Optionally, the data are periodically communicated to a remote site via a network, e.g., over the Internet. The device and associated software used to process the data can be used to characterize activities conducted by a prosthesis user, to determine pistoning or threatening interface stress distributions between the limb and socket, mal-alignment of the socket, use of improper components, and other possibly undesired conditions that the amputee patient using the prosthesis may be experiencing.

Abstract: A system for monitoring strain as an indicator of biological conditions, such as spinal fusion, glucose levels, spinal loading, and heart rate. The system includes an inter-digitated capacitor sensor, and RF transmitter, and an associated antenna, all of which are microminiature or microscopic in size and can be implanted in a biological host such as a human or animal. An inductively coupled power supply is also employed to avoid the need for implantation of chemical batteries. Power is provided to the sensor and transmitter, and data is transmitted from the sensor, when an external receiving device, such as a handheld RF ID type receiver, is placed proximate the location of the implanted sensor, transmitter and inductively coupled power supply. The implanted sensor, transmitter and inductively coupled power supply can be left in place permanently or removed when desired.

Abstract: Apparatus and method for detecting metal disturbance during a medical procedure includes a probe having an insertion tube, a joint, and a joint sensor for sensing a position of the insertion tube. The joint sensor comprises first and second subassemblies having coils. A processor is used for measuring force using the joint sensor, and having a pre-established baseline value stored therein. The processor detects changes in a position of the insertion tube by applying current to one coil and measures a signal output by a remainder of the other coils. The signal output by a remainder of the coils defines a pickup value, wherein the processor compares the pickup value to the pre-established baseline value and identifies presence of metal when the pickup value is outside of a range of the pre-established baseline value.

Abstract: The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s.

Abstract: A system and method for evaluating an activity includes an article of clothing provided with a sensor capable of detecting the impact of the article of clothing, such as a shoe, on a surface. A system receives and interprets the pattern of impacts made during the performance of the activity. The system compares these impacts with those of a target routine. Iterations of the same performance may be stored in the system so that ongoing progress may be measured. The system may be used to enhance class teaching, in the home, or for Internet competition. The activity may include dance, yoga, martial arts, or similar activities.

Abstract: A system and method for evaluating an activity includes an article of clothing provided with a sensor capable of detecting the impact of the article of clothing, such as a shoe, on a surface. A system receives and interprets the pattern of impacts made during the performance of the activity. The system compares these impacts with those of a target routine. Iterations of the same performance may be stored in the system so that ongoing progress may be measured. The system may be used to enhance class teaching, in the home, or for Internet competition. The activity may include dance, yoga, martial arts, or similar activities.

Abstract: An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.

Abstract: An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.

Abstract: Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.

Abstract: [Issue] To provide a guidewire insertion aid which is very easy to operate because a lubricated guidewire can be easily fed out. [Means of Resolution] A guidewire insertion aid 11 according to the present invention is used for feeding out a guidewire 1 inserted in a housing 2 in order to insert said guidewire into the lumen of a piece of medical equipment. The insertion aid 11 comprises: a main body 21, a housing support part 22 and a guidewire support part 26. A sliding contact part 28 is disposed between the housing support part 22 and the guidewire support part 26. The sliding contact part 28 extends in the lengthwise direction of the main body and has a sliding contact surface 28 for the guidewire 1. A feed-out member 51 is provided on the main body 21 and has a water-retentive water-retention member 52. The feed-out member 51 is disposed with the water-retention member 52 side thereof facing towards the sliding contact surface 29.

Abstract: Electrical impedance myography (EIM) can be used for the assessment and diagnosis of muscular disorders. EIM includes applying an electrical signal to a region of tissue and measuring a resulting signal. A characteristic of the region of tissue is determined based on the measurement. Performing EIM at different frequencies and/or different angular orientations with respect to a muscle can aid in the assessment and diagnosis. Devices are described that facilitate assessment and diagnosis using EIM.

Abstract: A method for the automated removal of a stimulus artifact from an electrophysiological signal waveform, wherein the novel method comprises: providing a model of the stimulus artifact that is physically derived and is based on known properties of the electrophysiological signal waveform acquisition hardware and stimulator; and filtering the stimulus artifact out of the electrophysiological signal waveform using the model.

Abstract: A coupling wire guide for intracorporeal procedures that may be coupled to a previously introduced wire guide, thereby permitting introduction of the coupling wire guide separately and identically in a manner that is both reliable as well as traceable. One embodiment of the wire guide includes a main body having a distal end and a tip portion connected to the distal end of the main body. The tip portion defines an axial passageway having a distal opening and a proximal opening, the passageway being sized to receive a second wire guide therein. The tip portion includes a linking member connected to the distal end of the main body to provide a secure connection between the distal end of the main body and the tip portion.

Abstract: A surgical instrument configured to deliver electrical energy to tissue of a patient includes a handle, a first conductor, and a second conductor. The surgical instrument further includes a first electrode with a first distal portion, a second electrode with a second distal portion, and a third electrode with a third distal portion, wherein each distal portion is configured to contact the tissue. The second distal portion surrounds the first distal portion and the third distal portion surrounds the second distal portion. A first gap is defined between the first distal portion and the second distal portion. A second gap is defined between the second distal portion and the third distal portion. The first electrode includes a sharp end configured to penetrate the tissue and the second distal portion includes a plurality of projections extending toward third distal portion.

Abstract: The present invention relates to embodiments which enable repetitive measurement and monitoring of the load applied to an apparatus, in a system, and/or by a method which may exceed a predetermined threshold of weight. Specifically, the present invention relates to weight monitoring apparatus, locomotion monitoring apparatus, a gait-response apparatus, a weight monitoring system, and a therapeutic load monitoring method.

Abstract: An exemplary embodiment includes acquiring an electroneurogram of the right carotid sinus nerve or the left carotid sinus nerve, analyzing the electroneurogram for at least one of chemosensory information and barosensory information and calling for one or more therapeutic actions based at least in part on the analyzing. Therapeutic actions may aim to treat conditions such as sleep apnea, an increase in metabolic demand, hypoglycemia, hypertension, renal failure, and congestive heart failure. Other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: The arrangement in a tonometer has a probe that is brought into contact with the surface of the eye and the intraocular pressure in the eye is derived from the variations in the velocity of the probe. The probe is formed of a piece of a non-magnetic substance. The arrangement includes a holder located in the tubular component and attached to a shaft providing the force for the measurement, in which holder there is a guiding means for guiding a movement of the probe along an internal surface of the tubular component.

Abstract: The visual and/or visualization skills of a subject may be tested and/or trained using systems and methods in accordance with the present invention. Visual stimuli may be presented to a test subject. Measurements relating to the performance of the subject, such as stability information, eye movement data, physiological information, or other information, may be made both with and without visual stimuli being provided to a subject. Similar measurements may be made while the subject visualizes the visual stimuli, and the collected data may be compared to evaluate the subject's ability to visualize visual stimuli. Secondary stimuli may also be provided to subject as part of this process, or mental activities may be required by subject as well.

Abstract: A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.