Patents Examined by Adam Yamasaki Ring
  • MUC16 monoclonal antibody and uses thereof
    Patent number: 11773183
    Abstract: The present document describes an antibody or an antigen-binding fragment that bind to O-glycan mucin-type glycoprotein MUC16 comprising three variable heavy domain complementarity determining regions (CDR)(CDR H1, H2 and H3), and three variable lighy domain CDR (CDR L1, L2 and L3). The present invention also relates to pharmaceutical compositions, nucleic acid vectors, cells comprising the nucleic acid vectors, and methods of inhibiting tumor growth of a tumor expressing O-glycan mucin-type glycoprotein MUC16.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 3, 2023
    Assignee: QUEST PHARMATECH INC.
    Inventors: Ragupathy Madiyalakan, Michael Hollingsworth, Prakash Radhakrishnan
  • Bispecific antibody and uses thereof
    Patent number: 11718671
    Abstract: Provided is a novel antibody and a method for treating breast cancer. More specifically, the present disclosure relates to a bispecific antibody targeting CD3 and a tumor antigen target such as HER2, a preparation method, and uses thereof. The present disclosure also relates to a composition containing said antibody and a method for treating cancer by using the antibody.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: August 8, 2023
    Assignee: Excelmab, Inc.
    Inventors: Wenjun Zhang, Cuijuan Chen, Xuemei Wei, Tonghui Luo