Patents Examined by Alan L. Rohman
  • Quinuclidyl- and tropanyl-pyridyl ethers as 5-HT.sub.3 receptor antagonists
    Patent number: 4921860
    Abstract: Pyridyl ethers of formula ##STR1## [where R is hydrogen, or 1 to 4 hydroxy, alkyl, alkoxy, amino, alkylamino, dialkylamino, halogen, trifluoromethyl, phenyl, halophenyl, alkyphenyl, alkoxyphenyl, carboxy, carboxamide, nitro, thiol or alkylthio substituents and B is quinuclidyl or tyopanyl] are useful for the treatment of conditions which respond to antagonism of 5 - HT.sub.3 receptors e.g. the treatment of migraine, emesis, anxiety, gastro-intestinal disorders and psychotic disorders.
    Type: Grant
    Filed: August 1, 1988
    Date of Patent: May 1, 1990
    Assignee: John Wyeth and Brother, Limited
    Inventor: Ian A. Cliffe