Abstract: A fluid processing system includes a fluid processing unit and a tubing arrangement providing fluid flow to and from the fluid processing unit. The tubing arrangement includes one or more flow cells and the fluid processing unit is selected from a unit comprising a single use tangential flow filtration mobile skid and a unit comprising a device for chromatographic separation. Each one of the flow cells includes a body having an inlet and an outlet and a fluid flow channel extending from the inlet to the outlet of the body.

Abstract: Provided is an automatic analyzer capable of simplifying control of a holding unit that holds a plurality of containers having access to an aspiration nozzle whose position is fixed and that rotates and moves up and down. The automatic analyzer includes an aspiration nozzle whose position is fixed and that aspirates reaction liquid or reagent, and a holding unit that holds a plurality of containers accommodating the reaction liquid or the reagent, and that rotates and moves t up and down. The holding unit holds at least three of the containers, and an angle between adjacent containers is an integer multiple of a predetermined angle. The angle between adjacent containers is an angle between adjacent containers in a circumferential direction and an angle around a rotation center of the holding unit.

Abstract: An automatic analyzer comprises a reagent storage unit, a reaction promotion unit, and an unused container providing unit. The reaction promotion unit is between the reagent storage unit and the unused container providing unit in a left-right direction, and is on a rear side from the reagent storage unit and the unused container providing unit in a front-rear direction. In the automatic analyzer, a cover covering the reaction promotion unit is with a first fitting portion, a second fitting portion, and a third fitting portion located between the first and the second fitting portion in the left-right direction and a handle that is between the first and the second fitting portion in the left-right direction and on a rear side of the third fitting portion in the front-rear direction. The first and the second fitting portion are high in positioning functionality. The third fitting portion is low in positioning functionality.

Abstract: An automatic analyzer performs a dispensing operation with high throughput while reducing a risk of carry-over of a reagent that includes first and second dispensing operations. The second dispensing operation includes a first procedure of aspirating a sample accommodated by a dispensing nozzle, a second procedure of discharging the aspirated sample to a first reaction container, a third procedure in which a cleaning tank cleans an inner side and an outer side of the dispensing nozzle after the second procedure, a fourth procedure of aspirating the reagent accommodated in a reagent container after the third procedure, a fifth procedure B5 in which the cleaning tank cleans the outer side of the dispensing nozzle after the fourth procedure, a sixth procedure of aspirating the sample accommodated in the first reaction container after the fifth procedure, and a seventh procedure of discharging the reagent and the sample to a second reaction container.

Abstract: A filtration module for filtering a process medium in a bioprocess including a process flow path for a process medium, a filter membrane coupled to the process flow path, and a sampling membrane coupled both to the process flow path and to a sampling flow path for extracting a sample from the process medium. The sampling flow path guides the extracted sample to a sampling outlet of the filtration module or to an analyzer integrated into the filtration module. A filtration assembly including the filtration module and an analyzer coupled to the sampling outlet of the filtration module. A method of sampling during a bioprocess including providing such a filtration module, urging a process medium through the process flow path, filtering the process medium by using the filter membrane, extracting a sample from the process medium by using the sampling membrane, and guiding the extracted sample to a sampling outlet.

Abstract: A cell analysis device includes a determination target identifier extraction portion configured to extract a determination target identifier that is information indicating an identification substance associated with a determination target cell that is a cell of a determination target from a table indicating a corresponding relationship between the cell and the identification substance for each compartment with respect to compartments flowing along a flow path including the cell and the identification substance that is a substance associated with the cell, an identifier acquisition portion configured to acquire the identifier that is the information for identifying the identification substance included in the compartments flowing along the flow path, a determination portion configured to determine a compartment including the determination target cell among the compartments flowing along the flow path on the basis of the identifier acquired by the identifier acquisition portion and the determination target iden

Abstract: An ultrasound indicating (USI) device and method for monitoring ultrasonication is provided. The USI device comprises a container comprising a USI formulation. The USI formulation comprises an organic liquid, a pH dye and an activator.

Abstract: Embodiments disclosed herein relate to methods and systems for performing an automated assay, and particularly to performing an assay on a plurality of samples on an automated instrument.

Abstract: A multi-channel head of a liquid handling apparatus for aspirating and dispensing a metered amount of liquid is configured to attach an array of disposable tips in a pick-up action, in which the multi-channel head is lowered relative to the disposable tips so as to insert each connector into an internal passageway of a corresponding disposable tip by an amount sufficient to bring an upper collar of the disposable tips into contact with an underside of the alignment plate which in turn deforms the elastomeric seal against the tip internal passageway so as to form a sealing contact therewith. An alignment action is thereafter performed in which the alignment plate is moved relative to connectors by an amount sufficient to close any gap between the underside of the alignment plate and the upper surface of the tip collars that arises due to e.g., relaxation of the deformed seals.

Abstract: A cost-effective and limited interaction explosive detector for dangerous, illegal, and/or illicit substances such as explosives, flammable or volatile fluids, and/or other appropriate substances is described. The explosive detector may be integrated into various containers or packages, such as cardboard boxes, paper envelopes, metal shipping containers, and/or other containers or packaging. The integrated explosive detector may provide a visual indication when a subject substance is encountered. The integrated explosive detector may include a port or vent that allows for ambient flow of fluids, such as air, between an interior of the container and the outside environment.

Abstract: The present invention relates to a beta-component of a transfer system for a sterile isolation region, a sterile isolation region, an aseptic filling system, and a method of operating such a filling system.

Abstract: An NMR spectrum is acquired from a nucleus of interest in a solvent included in a sample solution. A spectrum analyzer analyzes a number of splits, a splitting interval, a number of signals, and a signal interval based on the NMR spectrum. Based on these characteristic quantities, an identifier identifies the solvent. In another configuration, a plurality of NMR spectra acquired from a plurality of nuclei of interest included in the solvent may be analyzed.

Abstract: An insert for a holding device for reliably and accurately assessing a small volume of blood in a fluid, such as in a volume of surgical fluid collected during a surgical procedure, is provided. The insert may include a circular shelf having an outside perimeter configured to fit up against an inside perimeter of a holding device. The insert may include a center opening. The insert may include a conically-shaped collection cone disposed in the center opening. The collection cone may include a length, an interior surface comprising a red blood cell flocculant coating, a gradually decreasing perimeter terminating in a bottom apex, and a series of graduated volumetric markings along the length of the collection cone.

Abstract: A sample analysis system, method and a cell image analysis device. The sample analysis system includes a blood cell analyzer, a smear preparation apparatus, a cell image analysis apparatus, and a controller. The controller obtains a test result of at least one sample from the blood cell analyzer. When one sample needs to be analyzed by the cell image analysis device, the controller can further control an imaging condition used by the cell image analysis device according to a value of at least one type of cells in the test result of the sample, such that the cell image analysis device can automatically selects an imaging condition matching the test result for imaging according to different test results of the sample. Therefore, a matching imaging condition is used to specifically capture and analyze cell images of a smear of the sample, thereby improving processing efficiency and accuracy.

Abstract: An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for measuring serum amyloid A, which enable simple and rapid measurement of serum amyloid A by promoting dissociation of the serum amyloid A from HDL and carrying out an antigen-antibody reaction. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, at least one nonionic surfactant having an HLB value of 17 to 20, which is defined by (inorganicity value/organicity value)×10, and a molecular weight of 1000 or less, and a buffer capable of adjusting a pH of a reaction solution to be in a range of 5.5 to 7.0 or a range of 8.5 to 9.0.

Abstract: A flow cell of the flow cytometer of the present invention includes: a sample flow path through which a sample fluid containing a sample flows; and a sample fluid supply portion which communicates with an upstream end of the sample flow path in the sample fluid flow direction and supplies the sample fluid to the sample flow path, wherein the sample fluid supply portion includes a plurality of sample opening portions which supply a sample fluid to the sample flow path, a cleaning liquid supply opening portion to which a second tube is connectable and which supplies a cleaning liquid for cleaning the sample fluid supply portion, and a cleaning liquid discharge opening portion to which a first tube is connectable and which discharges the cleaning liquid from the sample fluid supply portion.

Abstract: The present invention relates to a mini-pipette, and more particularly, to a mini-pipette which has capacity varying means that can vary the movement distance of a push button reciprocating in the outer body to generate suction force so that a variety of samples can be easily collected. The present invention provides a mini-pipette comprising: an outer body having a hollow movement space and a suction passage formed at a lower part of the outer body; a push button for generating negative or positive pressure in the suction passage while reciprocating in the movement space of the outer body; elastic means for elastically supporting the push button in the movement space; and a capacity varying means formed inside the outer body, for varying a movement distance of the push button in the movement space.

Abstract: An analyzer having an inner chassis surrounded by a housing includes sample and dilution probes, a mixing housing including first and second mixing chambers, a flow cytometer including a flow cell, and sample and sheath pumps configured to perform first and second pluralities of tasks, respectively. The first plurality of tasks includes: aspirating sample into the sample probe, dispensing sample from the sample probe into the first and second mixing chambers, delivering first sample-dilution fluid mixture to the flow cell, and delivering second sample-dilution fluid mixture to the flow cell. The second plurality of tasks includes: dispensing sheath to the flow cell in cooperation with the delivery of the first sample-dilution fluid mixture to the flow cell, and dispensing sheath to the flow cell in cooperation with the delivery of the second sample-dilution fluid mixture to the flow cell.

Abstract: A photodiode (112, 200, 400, 500) includes a semiconductor substrate (210) having a first surface (211) and a second surface (212, 412, 512), and a light sensing junction (220) located adjacent to the first surface (211). The second surface (212, 412, 512) is located opposite the first surface (211), and the second surface (212, 412, 512) includes a concave surface covering a recessed region (415, 515) in the semiconductor substrate (210).

Abstract: A system for monitoring the alkalinity of a treatment liquid in a treatment tank includes a reaction tank; an indicator burette which drops an indicator into the reaction tank; a reagent burette which drops an acidic reagent into the reaction tank; a probe-type absorptiometer to be inserted into the reaction tank; a measuring device which analyzes the transmittance of a solution detected by the absorptiometer to calculate the alkalinity; a first system that collects the treatment liquid from the treatment tank for storing and supplies the treatment liquid to the reaction tank; a control device which controls the operation of the first system so as to supply the treatment liquid to the reaction tank, outputs a completion signal to the measuring device, and controls a discharge system so as to discharge the treatment liquid in the reaction tank, when the calculation of alkalinity by the measuring device is completed.