Abstract: An evaluation system including a hardware system for collecting real-time data for evaluating sleeping comfort performance of a bedding system is disclosed. The hardware system includes a thermal and moisture comfort measurement system, a thermal and moisture comfort control system, a biomechanical comfort control system, and a biomechanical comfort measurement system. The evaluation system also includes a computational system having a processor and a tactile database, and a portable device. The computational system is configured to receive and process the real-time data from the hardware system, and is communicatively connected to the portable device for transmitting real-time data for evaluating the bedding system and adjusting the hardware system.

Abstract: An apparatus and methods for detection of estrus and optimal time for embryo transfer or artificial insemination in animals. An arched polycarbonate housing is attached to an animal. A circuit board is disposed within the housing. A rechargeable battery mounted on the circuit board provides power to the apparatus. A switch mounted on the circuit board is actuated when a breeding behavior occurs. A controller mounted on the circuit board detects actuations of the switch to generate data indicative of breeding behavior. A transmitter transmits data indicative of breeding behavior to a remote receiver.

Abstract: A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

Abstract: In some examples, an apparatus comprises a platform having an upper surface to contact a plantar surface of a human foot positioned on the platform, a first pressure sensor to sense a pressure applied to the upper surface by a heel of the human foot, and a first probe extending through an opening in the platform and movable vertically upward through the opening to probe an adipose layer on a bottom of the heel. The apparatus also comprises a first actuator to displace the first probe upwardly against the adipose layer with a predetermined force, and a linear displacement sensor to sense a vertical displacement of the first probe.

Abstract: A rotation monitoring system may be attached to a limb and can identify ranges of motion that are associated with injuries or poor performance. In some embodiments, the device is designed to monitor flexion and orientation of joints and limbs, developed specifically around identifying stress concentrating behavior on the ACL. Tests performed show that the designed device can read flexion and orientation of the knee, is durable enough to be used in real-world conditions, and does not impede on the subject's movements.

Abstract: A device that non-invasively detects objects beneath or around the foot or a foot position and transmits signals which are processed and then output via an output device on a skin surface not affected by a neurological deficit, such as the hands or thighs. This device is suitable for subjects with diabetic neuropathy who have lost sensation in their feet and are at risk of punctures, cuts or other physical damage and at risk of sprains, strains or falls due to lack of an ability to detect objects underfoot and foot position.

Abstract: A biological information measuring apparatus includes a detector, a measuring unit, a calculator, and a determining unit. The detector detects pulse waves continuously. The measuring unit measures first biological information. The calculator calculates second biological information from the pulse waves based on the first biological information. The measuring unit suspends the measurement and resumes the measurement after a lapse of a period in a case where the determining unit does not determine that the result of measurement is normal, and the measuring unit continues the measurement in other cases where the body motion is not generated, the pulse waves are not irregular or the blood pressure value fails to vary.

Abstract: A system and method for rehabilitation and recovery using adaptive surface electromyographic sensing and visualization is disclosed. The system uses surface electromyography (sEMG) sensors to identify signals of intent from patients with physical disabilities and then uses these signals to interact with a computer system designed to create repetitive practice in a manner that promotes neurological recovery. A machine teaming module analyses body signals picked up during patient movement attempts and converts these body signals to a visual representation of the intended movement by way of a virtual body or virtual body part displayed on a computer display, display glasses, or the like. The system thus allows for very early patient therapy, providing early benefits to rehabilitation therapy not heretofore possible. The virtual reality or augmented reality environment provides a patient with very early visual reinforcement of beneficial muscle activation patterns.

Abstract: Disclosed is a system and method for in-situ and instantaneous measurement of a pressure gradient by real-time localized pressure measurement with two or more pressure sensors, operating with respect to blood pressure gradient across the aortic valve, or other heart valves, and associated regurgitation of blood flow due to leakage resulting from insufficient valve closure. The system includes a multi-sensor catheter, with sensors arranged along the length of the distal segment of the catheter body, spaced apart to provide simultaneous pressure measurement on either side of the valves of the heart, in addition to one or more lumina in the core of the catheter that will provide a path for introduction of diagnostic fluids which flow out through a multitude of holes in the body of the distal segment of the catheter body.

Abstract: A blood glucose monitoring and controlling system includes a detecting device and a liquid supplying device. The detecting device includes a first microneedle patch, a liquid pumping actuator, a sensor and a monitoring and controlling chip. The liquid supplying device includes a second microneedle patch, a liquid supplying actuator, a liquid supplying chamber and a liquid supplying and controlling chip. The detecting device is used to measure the blood glucose level of the user, and the liquid supplying device is used to supply insulin liquid. While the detecting device measures that the blood glucose level of the user is abnormal, the liquid supplying device is actuated to inject the insulin liquid into the user's body, thereby stabilizing the user's blood glucose level constantly.

Abstract: In one embodiment, a device for in vivo tissue evaluation includes an elongated manipulator including an elongated proximal tube and an articulable distal portion, and a sensor provided at a distal end of the articulable distal portion, the sensor including a sensor head configured to be pressed against tissue and measure a reaction force of the tissue.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for supporting components of an implantable medical device. The apparatuses, systems, and methods may include a first electrode and a second electrode and a scaffold assembly configured to support the first electrode and the second electrode.

Abstract: Systems, devices, and methods are disclosed for the purpose of quantitatively determining the susceptibility of a human subject to injure their Anterior Cruciate Ligament (ACL). A method for determining injury susceptibility scores or risk categories includes determining hip extension angles and knee varus angles during the performance of a stork test and determining hip abduction angles during a squat test. Determination of angles during certain movements may be achieved using various systems and devices, including wearable devices.

Abstract: Pressure sensing guidewire assemblies are described herein where the guidewire assembly may be comprised of an elongate guidewire body and multiple pressure sensors secured near or at a distal end of the guidewire body. The signals obtained from the guidewire connectors and aortic sensor modules may be synchronized to minimize signal acquisition delays. The signals may be further processed to equalize the pressure waveforms by shifting the connector waveform to align correctly with the aortic module waveform and improve output signals.

Abstract: A method of determining one or more vital sign parameters by a wireless vital-sign measurement device comprises: measuring motion information of a user wearing the wireless measurement device, the measurement device being in the idle mode in which at least one opto-electronic sensor in the measurement device is deactivated; switching the measurement device in an active mode if the motion information is below a predetermined threshold, wherein in the active mode the at least one opto-electronic sensor is activated; during a predetermined measuring period, exposing part of a skin tissue of the user to light and measuring one or more optical response signals associated with the exposed skin tissue and the motion sensor measuring motion information associated with movements of the user; and, selecting or rejecting one or more pulses in the one or more optical response signals on the basis of the motion information measured during the measuring period and determining one or more vital sign parameters on the basis

Abstract: A monitoring system configured to measure the user's health-related parameters while in a certain state is disclosed. Based on whether the user is in the certain state and/or one or more criteria being met, the monitoring system can perform a physiological measurement such as a blood pressure measurement. The monitoring system can be capable of dynamically adjusting the measurement parameters, criteria, and acquired information based one or more scalers. The criteria can be based on user states or conditions such that user disruptions can be reduced and the measurement accuracy and/or efficiency can be enhanced. The monitoring system can also measure the user's parameters during the measurement and may abort the measurement if the measurement may not have accurate information and/or to reduce any disruption to the user. Alternatively, the measurement can be annotated so that the measurement can be used during data interpretation with certain qualifiers attached.

Abstract: A blood sequestration device configured to isolate an initial, potentially contaminated portion of blood from the flow of blood of a patient, prior to directing the flow of blood to an outlet port where the blood can be accessed. The blood sequestration device including a body member having an interior wall defining a fluid conduit having a distal portion, a first proximal portion, and a second proximal portion, wherein the first proximal portion defines a sequestration chamber configured to isolate an initial portion of blood of a flow of blood, a vent path configured to enable the escape of gas initially trapped within the sequestration chamber.

Abstract: An illumination source may be configured to illuminate the skin of the user. An illumination detector may detect electromagnetic radiation reflected of the skin of the user. A compensation module may be configured to determine the position of the skin of the user relative to the illumination detector. A processor may be configured to determine a heart rate of the user by analyzing information corresponding to an amount of the electromagnetic radiation detected by the illumination detector. The processor may also determine the heart rate of the user by compensating for the position of the skin of the user as determined by the compensation module.

Abstract: A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.