Patents Examined by Alexei Bykhovski
  • Patent number: 12172007
    Abstract: A method of treating cancer is disclosed. The method involves applying one or more direct current electric fields (DC-EFs) to a subject and administering to the subject an additional treatment selected from the group consisting of radiation, an effective amount of one or more chemotherapy agents, SapC-DOPS, anti-phosphatidylserine targeted drugs, and combinations thereof.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: December 24, 2024
    Assignee: University of Cincinnati
    Inventors: Xiaoyang Qi, Ahmet Kaynak, Daria Narmoneva, Andrei Kogan
  • Patent number: 12161299
    Abstract: A cover member includes: a sheath that is formed in a cylindrical shape for receiving a shaft; and a tubular portion that is attached to a distal end of the sheath. The tubular portion being formed such that an outer dimension of a distal end portion of the tubular portion in a first direction is smaller than an outer dimension of a proximal end portion of the tubular portion in the first direction and/or an outer dimension of the distal end portion in a second direction is smaller than an outer dimension of the proximal end portion in the second direction.
    Type: Grant
    Filed: September 13, 2022
    Date of Patent: December 10, 2024
    Assignee: OLYMPUS CORPORATION
    Inventors: Hiroshi Minami, Masami Oshida, Masato Inoue
  • Patent number: 12156706
    Abstract: A system and method for performing an automated medical procedure is provided. The method may include positioning an effector unit over a patient, acquiring medical imagery of the patient, analyzing the medical imagery using at least one processor to determine a location, and positioning a subunit of the effector unit to perform the automated medical procedure at the location. The automated medical procedure may be performed using at least one of a plurality of subunits of the effector unit. The automated medical procedure may be a body fluid aspiration procedure and one of the plurality of subunits of the effector unit may include a fluid aspirating cannula. Multiple subunits may be sequentially used to perform the procedure.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: December 3, 2024
    Assignee: University of lowa Research Foundation
    Inventor: Sandeep Laroia
  • Patent number: 12150777
    Abstract: Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: November 26, 2024
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Amit Etkin, Yu Zhang, Greg Fonzo, Madhukar Trivedi
  • Patent number: 12150747
    Abstract: Even when imaging is aborted, data collected so far is utilized in image reconstruction, thereby enhancing examination efficiency. A certain priority imaging data available for image reconstruction by a fast-imaging method is determined, when collecting k-space data according to a predetermined imaging method. If collection of the certain priority imaging data is completed when imaging is aborted, imaging reconstruction is executed using the priority imaging data. The priority imaging data is determined based on a relationship between the imaging method under execution, and the fast-imaging method underlying determination of the priority imaging data.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: November 26, 2024
    Assignee: FUJIFILM CORPORATION
    Inventor: Yusuke Hoshino
  • Patent number: 12144596
    Abstract: Method and systems are provided for reliable, convenient, self-administered, and cost-effective determination of central venous pressure. The noninvasive method and apparatus use changes in transmural pressure to create detectable changes in peripheral venous vascular volume for the determination of central venous pressure. Transmural pressure changes can be manifested by intravascular or extravascular pressure changes. The system is noninvasive and uses optical measurements of venous volume in the presence of transmural pressure changes. The relationship between the transmural pressure change and the change in vascular venous volume is combined with anatomical measurements to determine the central venous pressure of the subject. Central venous pressure can be used to determine hemodynamic status of the subject to include fluid overload in the heart failure patient.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: November 19, 2024
    Assignee: MEDICI TECHNOLOGIES LLC
    Inventors: Mark Ries Robinson, Elena A Allen, Fahimeh Salehpour
  • Patent number: 12138121
    Abstract: An intravascular sensor device can be used to guide treatment of a diseased blood vessel in the body of a patient. In some examples, the intravascular sensor device includes a pressure sensor and an ultrasound transducer. The intravascular sensor device is used to measure a pressure within the diseased blood vessel and acquire an ultrasound image of the diseased blood vessel. The pressure may be measured during hyperemic blood flow that is caused by a pharmacologic vasodilator drug. The measured pressure can be used to calculate a fractional flow reserve value. The ultrasound image can be used to determine a physical dimension of the blood vessel, such as cross-sectional area. The fractional flow reserve value and physical dimensions of the blood vessel can be used to optimize patient treatment.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: November 12, 2024
    Assignee: Zed Medical, Inc.
    Inventors: Thomas C. Moore, Kendall R. Waters, Robert Zelenka
  • Patent number: 12121367
    Abstract: A wrist-watch back case for replacing existing back case of a timekeeping device or to be attached thereto is provided. The back case comprises a casing comprising a bottom wall and a side wall thereby defining an inner empty space, at least five openings at the bottom wall, an optoelectronic board, at least two paired radiation sources and at least one radiation detector. Methods for measuring biomarkers, systems and a watchband are also provided.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: October 22, 2024
    Assignee: TRAQBEAT TECHNOLOGIES PRIVATE COMPANY
    Inventors: Vangelis Sakkalis, Matthaios Pediaditis, Emmanouil Georgios Spanakis, Giannis Zacharakis
  • Patent number: 12121399
    Abstract: Ultrasound imaging systems for automatically adjusting settings according to an position and/or orientation of one or more interfaces. The ultrasound imaging systems can include a probe configured to send and receive ultrasound signals for performing a medical exam, a medical procedure, or both; and a processor configured to: select a diagnostics mode or a procedural mode based on an operating orientation of the ultrasound imaging system or a portion thereof, and adjust one or more settings of the imaging system according to the selected diagnostics mode or the selected procedural mode.
    Type: Grant
    Filed: April 21, 2023
    Date of Patent: October 22, 2024
    Assignee: FUJIFILM SONOSITE, INC.
    Inventors: Craig Chamberlain, Patrick Nally, Ben Dekock, Gina Kelly, Roger Swezey, Saeed Aliakbari
  • Patent number: 12109069
    Abstract: An ultrasound diagnostic apparatus (1) includes an ultrasound probe (2) and a diagnostic apparatus main body (3) that are wirelessly connected, the ultrasound probe (2) includes a detection unit that generates a complex baseband signal, a complex baseband signal processing unit (17) that performs high-pass processing and autocorrelation analysis processing on the complex baseband signal, a phase data generation unit (18) that generates phase data on the basis of the complex baseband signal, and a probe-side wireless communication circuit (20) that wirelessly transmits the phase data, and the diagnostic apparatus main body (3) includes a main body-side wireless communication circuit (31) that receives the wirelessly transmitted phase data, a complex signal generation unit (33) that generates a complex signal on the basis of the phase data, a color flow image generation unit (34) that generates a color flow image on the basis of the complex signal.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: October 8, 2024
    Assignee: FUJIFILM Corporation
    Inventor: Masafumi Noguchi
  • Patent number: 12102489
    Abstract: Methods and systems that provide quantitative assessments of in vivo thermal treatments, such as ablations, during image-guided surgeries using a high-resolution pre-operative MRI image segmented with a shape constrained and deformable mesh representations of brain structures and generating 3-D visualizations of thermally treated volumes during the thermal treatment that can provide near real time visual and quantitative feedback to a clinician.
    Type: Grant
    Filed: April 20, 2022
    Date of Patent: October 1, 2024
    Assignee: ClearPoint Neuro, Inc.
    Inventors: Lyubomir Georgiev Zagorchev, Christian Richard Osswald, Nicolas Gallo, Kamal Vij
  • Patent number: 12102412
    Abstract: A guidewire with a cross section of at least a part of its length, comprising a filling material (PLM), a lumen (LM) arranged inside the filling material (PLM) for accommodating an optical fiber (OF) with optical shape sensing properties. One or more stiffening elements (RD) are arranged inside the first material (PLM), wherein the stiffening element(s) (RD) is formed by a material having a higher axial stiffness than the filling material. A braiding structure (BR) encircles all of: the filling material (PLM), the lumen (LM), and the stiffening element(s) (RD). Such guidewire can be designed with a circular symmetric bending behavior, and is thus suitable as an interventional medical device, e.g. for endovascular procedures, and still it can provide optical shape sensing properties.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: October 1, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Franciscus Reinier Antonius Van Der Linde, Marcellinus Petrus Maria Cnoops, Rudolf Maria Jozef Voncken, Cornelius Antonius Nicolaas Maria Van Der Vleuten
  • Patent number: 12102481
    Abstract: A medical ultrasound system that includes an ultrasound probe and one of number of optional accessories attached to the ultrasound probe. The accessory exchanges data with the probe and receives power from the probe. The accessory includes processors and logic that governs it operation thereby adding functionality to the probe. The accessory receives input and provides output via any of a number of communication mechanisms, i.e., wireless, electrical, optical, RFID, IR, and the like. The accessory adds functionality to the probe, such as fiber optic shape sensing, obtaining electrical signals, obtaining bio-impedance measurements, tracking a needle, and determining the orientation of the probe. The accessory may include a needle guide, a triphalangeal support structure, or an acoustically transparent cap.
    Type: Grant
    Filed: June 3, 2022
    Date of Patent: October 1, 2024
    Assignee: Bard Access Systems, Inc.
    Inventors: Anthony K. Misener, Steffan Sowards, William Robert McLaughlin
  • Patent number: 12102482
    Abstract: The invention provides for a method for switching between fields of view of an ultrasound probe. The method begins by obtaining an anatomical model representing a region of interest of a subject and establishing a first field of view relative to an ultrasonic probe, wherein the first field of view comprises an initial portion of the region of interest. Ultrasound data is then obtained from the first field of view by way of the ultrasonic probe and a first anatomical feature is identified within the first field of view based on the ultrasound data. A location in digital space of the first field of view relative to the anatomical model is determined based on the first anatomical feature. A second field of view is then established based on the anatomical model and the first field of view, wherein the first field of view functions as a reference field of view. The field of view is then switched from the first field of view to the second field of view.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: October 1, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Frank Michael Weber, Irina Waechter-Stehle, Tobias Wissel, Arne Ewald, Matthias Lenga, Jochen Peters
  • Patent number: 12102488
    Abstract: The technology described in this document can be embodied in a viewing apparatus for a surgical device, the apparatus including a lens assembly including a first polarizer, a display device configured to present an image of a surgical scene, and a reflective surface oriented at an acute angle with respect to the display device such that light from the display device is reflected from the reflective surface towards the lens assembly. The first polarizer in the lens assembly is configured such that light reflected from the reflective surface passes through the first polarizer, and light reaching the first polarizer without being reflected from the reflective surface is substantially blocked.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: October 1, 2024
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Ian E. McDowall, Randal P. Goldberg, Yu-min Lee
  • Patent number: 12102414
    Abstract: The invention relates to a method of scanning for vascular ill health using a data set from an in vivo scan, the method including the steps of: (1) extracting blood vessel location data and blood vessel size data from the scan data set; (2) selecting a region in the extracted vessel location data; and (3) comparing the size data in the selected region to size data in a corresponding region of a normative data set to determine vascular health.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: October 1, 2024
    Assignees: 4DMedical Limited, Cedars-Sinai Medical Center
    Inventors: Chaminda Rajeev Samarage, Andreas Fouras, Heather Jones, Victor Tapson
  • Patent number: 12094612
    Abstract: A tumor diagnosis system and a construction method thereof, a terminal device and a storage medium are provided, wherein a radiomics signature is obtained by a radiomics signature-generation module in the tumor diagnosis system according to target radiomics information and clinical data information, based on a pre-trained radiomics signature model; a first classification comprehensive diagnosis result is obtained by a benign and malignant comprehensive classification module according to a ambient situation of a lesion outside an intestinal wall, the clinical data information and a first radiomics signature, based on a pre-trained first classification comprehensive diagnosis model; a second classification comprehensive diagnosis result is generated through a malignant focus sub-classification module based on a pre-trained second classification comprehensive diagnosis model, if the first classification comprehensive diagnosis result includes high-risk malignant information; and a final diagnosis result is obtai
    Type: Grant
    Filed: October 31, 2023
    Date of Patent: September 17, 2024
    Assignee: CANCER HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Qing Zhao, Hongmei Zhang, Xinming Zhao
  • Patent number: 12089999
    Abstract: An ultrasonic diagnostic apparatus includes an ultrasonic probe, a plurality of detectors, a measurer, and processing circuitry. The ultrasonic probe includes the plurality of transducers, and is configured to transmit an ultrasonic signal to a subject through each of the transducers, and receive, through each of the transducers, a reflected wave signal obtained when the transmitted ultrasonic signal has been reflected from an inside of a body of the subject and returned. Each of the plurality of detectors respectively corresponds to transducers and are configured to detect a reflected wave signal received by the corresponding transducer. The measurer configured to measures a reflected wave signal having an amplitude greater than an amplitude at which at least one of the detectors is saturated when determining a gain of the at least one of the plurality of detectors.
    Type: Grant
    Filed: February 15, 2022
    Date of Patent: September 17, 2024
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventor: Gen Nagano
  • Patent number: 12082974
    Abstract: Systems and methods to provide an ultrasound scanner that supports handset wireless network connectivity are described. An ultrasound scanner includes a transducer system that generates, as part of an ultrasound examination, ultrasound data based on reflections of ultrasound signals transmitted by the transducer system. The ultrasound scanner includes a first transceiver that communicates, over a first communication link, the ultrasound data to a display device that displays an ultrasound image based on the ultrasound data. The ultrasound scanner includes one or more additional transceivers that communicate, over a one or more additional communication links and simultaneously with the first transceiver communicating the ultrasound data over the first communication link, the ultrasound data through an access point of a care facility administering the ultrasound examination.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: September 10, 2024
    Assignees: FUJIFILM SONOSITE, INC., FUJIFILM CORPORATION
    Inventors: Craig Chamberlain, Christopher Howard, Harald Fiedler, Derek Jensen, Katsuya Yamamoto, Hiroshi Murakami, David Hoglund
  • Patent number: 12082774
    Abstract: A system for assisting endoscope tracking used to track a travel path of an endoscope probe within an organ includes three position sensors and three distance sensors which are surrounding an endoscope probe, and a computing device. The said three position sensors respectively sense a first coordinate, a second coordinate and a third coordinate relative to a navigation origin. The said three distance sensors respectively sense a first distance, a second distance and a third distance apart from an inner wall of the organ. The computing device obtains a position coordinate of the endoscope probe relative to the navigation origin according to the first coordinate, the second coordinate and the third coordinate. The computing device further determines whether to send a warning message according to the first distance, the second distance and the third distance.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: September 10, 2024
    Assignee: METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE
    Inventors: Yu-Sung Hsieh, Bing-Feng Huang