Abstract: A method for detecting the presence of contrast agent in the body of the patient initially transmits ultrasound pulses along respective acoustic scan lines, which pulses exhibit a fundamental transmission frequency. A set of returned signals are received along a respective scan line after each pulse transmission. The return signals are mathematically reconstructed to provide a first spectral component around the fundamental frequency and a second spectral component around a harmonic frequency. The peak amplitude of the reconstructed spectral components are compared to determine whether a contrast agent is present in the tissue, and hence to differentiate myocardium and perfused myocardium.

Abstract: An ultrasound system for continuous imaging and for controlling release of an encapsulated agent from a carrier comprises a housing secured to a patient's body, a transducer mounted within the housing, means for controlling the transducer to insonify the drug carrier with an ultrasonic signal and to thereby cause the release of the agent, and means for processing an ultrasonic echo signal to produce an image. Also, a method for controlling release of an encapsulated agent from a carrier comprises the steps of measuring a physiological parameter of a patient based on an ultrasonic echo signal, comparing the physiological parameter to a threshold, and transmitting an ultrasonic signal to insonify the carrier and thereby cause the release of the agent from the carrier in accord with the measured physiological parameter.

Abstract: An ultrasound system is described which can be turned off quickly by an operator command or in response to an interruption of a.c. power to the system. When a.c. power is cut off, the system switches to battery backup while a processor executes an orderly shutdown sequence. The system can completely shut down, or the state of the system can be minimally preserved by battery backup in either volatile or nonvolatile memory so that the system can restart without having to sequence through an entire bootup procedure. This enables the system to remain active even when the ultrasound system is unplugged and being moved.

Abstract: A medical imaging system provides increased detectability of targets such as membranes, tendons, muscle fibers and biopsy needles that have strong directional responses. This improved result is achieved by compounding multiple images generated by using only one or two transducer firings per ultrasound line. Speckle variance is also reduced as the result of spatial compounding, and this reduction improves the detectability of soft-tissue lesions.

Abstract: The present invention solves a problem that has been a barrier to development of high resolution ultrasonic imaging. It is based on an analysis that formulates the 5 problem of wave propagation in an inhomogeneous medium as a summation of an ideal wave and distortion waves. This analysis then leads to an apparatus that includes a forward propagation apparatus that enables measurement of the distortion waves and determination of corrections that are applied to originally received signals such that the ideal wave is left as the only basis for the final output signal. After signals are corrected, basic beamforming processes work as if the propagation medium was homogeneous such that ideal high resolution performance is achievable. The method is generally useful for improving any form of wave propagation system that is disturbed by inhomogeneities in the medium.

Abstract: A transducer probe has a fully populated, integrated, matrix array of acoustical transducers for ultrasound imaging, switchable in real time between two orthogonal 1.5D or 1.75D transducers arrays, consisting of tiled subarrays of transducers which may be switched in real time between vertical and horizontal strip arrays by integrated circuits directly attached to the subarrays, for performing a first level of transmit and receive beam forming functionality with either horizontal or vertical scanning. The integrated circuits include a summer circuit for reducing the output signals of each subarray to a single line, reducing the number of lines required in the cable or connection medium. An interface box mates to a host system and facilitates the switching and control function. Impedance matching in the integrated circuits between transducers and cable lines improves signal transmission in cables. Applications include medical imaging, materials testing and sonar systems.

Abstract: Ultrasonic scanning and diagnostics for cellular tissue are disclosed. An ultrasonic probe is moved across cellular tissue at a rate that is synchronized with the image capture rate of the ultrasonic scanner, to achieve a contiguous and complete set of scan images, of the tissue. The probe can be held in a single position as it is moved across the tissue, or it can be dynamically adjusted during the scan to provide optimal contact with the scanned tissue. The image data are captured and converted to a format that is easily stored and compatible with a viewer. The viewer allows playback of the scanned images in a manner that is optimized for screening for cancers and other anomalies. A location function allows the user to select a point of interest on an individual scan image, and choose another known reference point, and the function calculates and provides the distance from the reference point to the point of interest in three dimensions.

Abstract: An ultrasound system that generates compound images from component frames having decorrelated speckle patterns. Successive sets of distinct, speckle-affecting parameters are used to generate successive component frames for compounding, and are selected such that the successive component frames have decorrelated speckle patterns. The speckle-affecting parameters that are changed from frame to frame may be selected from a wide variety of parameters, including transmit beamformer parameters, receive beamformer parameters, and demodulator parameters. According to a preferred embodiment, the successive sets of speckle-affecting parameters differ from each other by at least two speckle-affecting parameters.

Abstract: The preferred embodiments described herein provide a medical diagnostic ultrasound imaging system and method in which a non-real-time operating system is used to transfer image data. In one preferred embodiment, a medical diagnostic ultrasound imaging system includes a central processing unit (“CPU”) located outside of the received signal path to transfer image data. The non-real-time operating system can be used, for example, to transfer image data from a hard disk to system memory for display, to transfer image data from system memory to the hard disk for storage, or to scroll image data to view a loop of image data.

Abstract: The preferred embodiments described herein provide a method and system for displaying medical data at an automatically-selected display resolution. In one preferred embodiment, medical data is automatically analyzed, and based on the analysis, a display resolution is automatically selected. The medical data is then displayed with the automatically-selected display resolution. By automatically selecting a display resolution based on an analysis of medical data, the appearance of medical data is optimized without conscious effort by a user. Other preferred embodiments are provided.

Abstract: An improved system and method to provide visualization of implantable leads, catheters, or other implantable devices is disclosed. According to the invention, an unmodified guiding device such as a stylet or guidewire is frictionally coupled to a vibration device. This guiding device is further inserted into the device to be visualized. When activated, the vibration device transfers longitudinal waves to the guiding device, which, in turn, transfers the waves to the device that is to be visualized. These waves are detected by an imaging device, which then generates a Doppler image of the implantable device. According to one aspect of the invention, the vibration device includes a piezoelectric actuator. According to another aspect of the invention, the frequency of the waves that are transferred by the vibration device is selectable.

Abstract: A method and system for identifying constrictions in a vessel are provided. Total blood volume flow is measured at various locations along the vessel. The total volume flow must be conserved. Regions with a different volume flow than expected (e.g. areas associated with a lower volume that violates conservation of flow) are identified as suspicious. Suspicious regions are likely associated with dropout artifact. Actual constrictions are determined from the geometry of images where the region is not suspicious.

Abstract: An ultrasound system and method for calculation and display of tissue deformation parameters, such as tissue Doppler and strain rate imaging, are disclosed. An ultrasound acquisition technique that allows a high frame rate in tissue velocity imaging or strain rate imaging is employed. With this acquisition technique the same ultrasound pulses are used for the tissue image and the Doppler based image. The number of beams used in Doppler subframes are increased to allow tissue visualization based only on Doppler subframes. A sliding window technique is used for processing.

Abstract: An ultrasound system comprising an ultrasound unit and a transducer. The transducer including a transducer housing integrating at least one element integrated and a first spatial locator unit. The ultrasound unit includes an imaging unit that receives an echo signal from the at least one element of the transducer and outputs echo data. A second spatial locator unit, in communication with the first spatial locator unit, is integrated with the ultrasound unit. The second spatial locator unit enables the determination of a location of the transducer housing.

Abstract: A keratome includes a head assembly having a cutting head and blade for cutting corneal tissue and an applanation member associated with the cutting head. The keratome includes an eyeball retaining structure and at least one sensor is associated with the keratome providing measurement of a respective at least one operative factor during cutting of the corneal tissue.

Abstract: Methods and apparatus for enhancing the capabilities of ultrasonic techniques through use of ultraharmonics are provided.

Abstract: Methods and a system are disclosed for processing an echocardiogram video of a patient's heart. The echocardiogram comprises at least a first sequence of consecutive video frames corresponding to a first view of the patient's heart concatenated with a second sequence of consecutive video frames corresponding to a second view of the patient's heart. The end-diastole phase of the patient's heart is monitored in each frame by detecting the electrocardiograph wave, and a key frame is selected upon the occurrence of the R-wave peak in the electrocardiograph wave in each of the first sequence of consecutive video frames and in the second sequence of consecutive video frames. The shape and color content of the echocardiogram image window is monitored in certain video frames, and a transition is detected when there is a change in the first feature between adjacent frames. A summary is generated which comprises by the video frames corresponding to the end-diastole phase.

Abstract: An ultrasonic diagnostic imaging system and method are described for performing fundamental frequency and second harmonic frequency imaging simultaneously. Transmit bursts are employed which include a first waveform component optimized for fundamental imaging and a second waveform component optimized for harmonic imaging. The first waveform component may be centered in the transducer passband, and the second waveform component may be located on the opposite side of the center of the transducer passband from its second harmonic frequency, for instance. Echoes received from the bursts are separated into fundamental and harmonic components and used to form separate fundamental and harmonic images or blended fundamental/harmonic images.

Abstract: Improved methods of signal processing for generating estimates of tissue strain are presented. These techniques generally employ the frequency shifting of post-compression spectral data to determine a scaling factor which approximates the applied tissue strain. The scaling factor can be determined by finding the maximum correlation between the frequency shifted post-compression data to the pre-compression data and can also be determined by minimizing the variance of the ratio of such data. Correlation tracking and maximum correlation magnitude techniques for improving the results of elastography are also presented.

Abstract: The preferred embodiments described herein relate to voice-enhanced diagnostic medical ultrasound imaging systems and review stations as well as to voice-related user interfaces. With these preferred embodiments, a user can interact with an imaging system or review station by issuing verbal commands instead of using a mouse, keyboard, or other user interface that requires physical manipulation by the user. This provides a very user-friendly interface, especially to those users who have difficulty navigating complex window and menu hierarchies or who have trouble manipulating pointing devices. This also improves patient flow and provides a more efficient report generation system. Voice feedback can also be used to allow the imaging system or review station to better communicate with a user.