Abstract: The invention relates to a composition of oil-in-water emulsion type comprising: —at least one polyol in a content ranging from 7% to 25% by weight relative to the total weight of the composition; —water in a content ranging from 60% to 90% by weight relative to the total weight of the composition; —at least two nonionic surfactants that are different from each other, chosen from a nonionic surfactant of ester type comprising a mixture of at least one unsaturated ester and of at least one diester of polyglycerol and a nonionic surfactant which is a fatty alcohol with a saturated, linear carbon-based chain containing from 14 to 26 carbon atoms; —at least one wax; —and the mass ratio [total amount of said nonionic surfactant(s) of ester type]/[total amount of said wax] ranges from 0.8 to 2, preferably from 1 to 1.5.
Type:
Grant
Filed:
December 21, 2017
Date of Patent:
November 29, 2022
Assignee:
L'OREAL
Inventors:
Sabine Roux, Elena Catalan-Martin, Chloé Laidboeur
Abstract: Use of a naturally glycosylated polyphenol, not containing nitrogen, as protective agent against the effects of ultraviolet irradiation on photo-degradable substances of structures.
Abstract: The present invention refers to a method for the synthesis of a biodegradable calcium release material that shows controlled ion release properties for tissue engineering, biomaterials containing the calcium particles as well as the calcium particles obtainable therefrom. By varying the treatment temperature of the described method, the calcium material shows different calcium release profiles. Contrary to a specific chemical composition such as CaCO3 which is associated to a specific calcium release profile, the present invention allows a manifold of compositions, with a manifold of calcium release profiles, all starting from a single specific chemical composition calcium precursor. Therefore, the invention also relates to the use of the controllable release, calcium material in tissue regeneration such as wound healing processes.
Type:
Grant
Filed:
May 31, 2018
Date of Patent:
November 8, 2022
Assignees:
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA (IBEC), UNIVERSITAT POLITECNICA DE CATALUNYA
Inventors:
Elisabeth Engel Lopez, Oscar Castano Linares, Joan Marti Munoz, Josep Anton Planell Estany
Abstract: Provided are compositions and methods for a scaffold coated with a primer coating and a mineral coating. Also provided is a composition for a scaffold having a mineral coating similar to bone. Also provided is a method for mineral coating a scaffold so as to promote mineral coating of the scaffold with a plate-like nanostructure and a carbonate-substituted, calcium-deficient hydroxyapatite phase.
Type:
Grant
Filed:
March 3, 2016
Date of Patent:
November 8, 2022
Assignee:
Warsaw Orthopedic, Inc.
Inventors:
Leenaporn Jongpaiboonkit, William L. Murphy, Sharon Virginia Schulzki
Abstract: The invention relates to compositions and methods for adjusting digestive or absorptive rates and ratio of foods or drinks or reducing a digestive solution. Particularly, the invention provides a composition comprising an insoluble dietary fiber and a prebiotic gel and its application in reducing digestive or absorptive rates and ratio of foods or drinks.
Abstract: The invention relates to a method for treating or preventing nausea and vomiting. The method comprises administering an eye drop composition comprising palonosetron or a pharmaceutically acceptable salt thereof to the eye of the subject. The ocular administration results in fast systemic absorption, improved bioavailability compared to oral route and extended elimination time.
Type:
Grant
Filed:
January 11, 2019
Date of Patent:
September 6, 2022
Assignee:
ORION CORPORATION
Inventors:
Jouko Levijoki, Sari Pappinen, Lasse Saloranta
Abstract: An oil-gel-form external preparation for skin contains a compound represented by the following General Formula (1), an isomer thereof, and/or a pharmaceutically acceptable salt thereof. A partially cross-linked methyl polysiloxane; allows easy penetration of the compound from the preparation into the skin while enhancing the percutaneous absorbability and improving the intradermal retentivity. In the formula, R1 represents a C1-C4 linear or branched alkyl group substituted by a carboxyl group(s), or a C1-C4 linear or branched alkyl group substituted by a carboxylic acid ester group(s) having a C1-C4 alkyl chain, and R2 and R3 each independently represent a C1-C4 linear or branched alkyl group.
Abstract: Methods of reducing injury to crop foliage and achieving weed control using encapsulated acetamide herbicides in pre-plant or preemergence crop plant applications are described. A composition comprising a first population of a particulate microencapsulated acetamide herbicide and a second population of a particulate microencapsulated acetamide herbicide is described wherein the application mixture exhibits a bimodal acetamide release profile. The compositions provide reduced crop injury through controlled herbicide release.
Type:
Grant
Filed:
March 12, 2018
Date of Patent:
August 16, 2022
Assignee:
Monsanto Technology LLC
Inventors:
Ronald J. Brinker, Matthew T. Faletti, Douglas A. Findley, Alejandro Perez-Jones, S. Douglas Prosch
Abstract: A chemical preservative including phenoxyethanol, 2-butyl-1,2-benzisothiazolin-3-one and N,N-bis(3-aminopropyl) dodecylamine; its use to inhibit and/or to control the growth of microorganisms in a technical composition.
Type:
Grant
Filed:
April 30, 2018
Date of Patent:
August 2, 2022
Assignee:
VINK CHEMICALS GMBH & CO. KG
Inventors:
Jennifer Knopf, Ralf Gradtke, Anne Gückel
Abstract: The invention relates to modified release oral formulations of therapeutic agents, including gamma hydroxybutyrate (GHB), paracetamol, codeine or oxycodone, which are resistant to alcohol induced dose dumping. Provided are formulations that have improved resistance to rapid release of the active ingredient in the presence of increasing amounts of alcohol. Also provided are formulations that can reduce or prevent the release of the active ingredient following exposure to alcohol-containing media. The invention also relates to methods of making the formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.
Abstract: The present invention may comprise stabilized metal nanoparticles that are stabilized with material from gum arabic. The nanoparticles of the invention may be manufactured with an environmentally friendly method for fabricating biocompatible stabilized metal nanoparticles. The coated metal nanoparticles may be introduced in vivo to conduct therapy for humans or animals.
Abstract: The invention relates to stable preparations of thymoquinone and methods of making and administering stable preparations of thymoquinone. Embodiments of the methods provide compositions comprising thymoquinone with phosphatidylcholine and/or guggulsterol and/or guggulsterol derivatives and/or sodium cholesteryl sulfate, in tablet, capsule, gel, or ointment forms, and method of administering the preparations.
Type:
Grant
Filed:
September 12, 2018
Date of Patent:
July 19, 2022
Assignee:
Jina Pharmaceuticals, Inc.
Inventors:
Shoukath M. Ali, Saifuddin Sheikh, Ateeq Ahmad, Moghis U. Ahmad, Paul Chen, Imran Ahmad
Abstract: The invention relates to an aerosol device comprising: a container containing a cosmetic composition which comprises at least one fixing polymer, and a dispensing head (3) comprising a body (5) and an end part (7) comprising at least two outlet orifices (12) configured to allow spraying of the composition about a longitudinal axis (Y) of the end part (7) in at least two different directions, the dispensing head (3) comprising at least first (15) and second (16) chambers, through which the composition stream successively passes before it exits via the outlet orifices (12).
Abstract: Disclosed are aqueous pharmaceutical compositions which provide sustained released delivery of corticosteroid compounds. The pharmaceutical composition comprises an insoluble corticosteroid; a soluble corticosteroid; and at least one viscosity enhancing agent. Also provided are methods for using the pharmaceutical compositions in an epidural injection, intra-articular injection, intra-lesional injection, or an intra-ocular injection.
Abstract: The present disclosure relates to compositions, including, hydrogel compositions useful as analgesics including cannabinoids, menthol and anesthetic in a composition formulated to be administrable to a non-human animal rectally as a suppository. The menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid.
Abstract: A drug delivery formulation for treating a mental illness or a central nervous system disorder is disclosed. The drug delivery formulation includes a microcapsule containing a biodegradable polymer and a drug and a crosslinked hydrogel and a method for preparing the same. The drug delivery formulation can slowly release a drug at a constant rate without a burst of drug release in the early stage of drug administration to maintain a constant blood drug level over a long period of time and thus enjoys the advantage of preventing excessive initial release of drug, thereby obtaining a desirable sustained release profile by single administration without necessity for multiple administrations divided at regular time intervals.
Type:
Grant
Filed:
February 8, 2018
Date of Patent:
May 24, 2022
Assignee:
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Abstract: A particle is provided that includes 5 wt % to 90 wt % of agricultural biomass, combustion residues, biosolids, or a combination thereof. A binder intermixed with the agricultural biomass, combustion residues, biosolids, or a combination thereof retains the mixture in the form of a particle. The resultant particle creates a use for existing waste streams while also improving soil quality. A process of stabilizing agricultural biomass, combustion residues, biosolids, or a combination thereof particles is also provided that includes combining agricultural biomass, combustion residues, biosolids, or a combination thereof with mineral and/or synthetic chemical fragments having a bulk density of greater than about 40 pounds per cubic foot and a sizing of about 100% passing through a 30 mesh screen and about 50% or more passing through a 200 mesh screen. By adding binder, a particle is formed that is deodorized and/or stabilized.
Type:
Grant
Filed:
March 14, 2011
Date of Patent:
May 17, 2022
Assignee:
THE ANDERSONS, INC.
Inventors:
Charles W. Anderson, Timothy D. Birthisel
Abstract: The present invention relates to the use of a composition containing 1,8-para-menthenethiol and 3-mercaptohexyl acetate, such as a plant extract and in particular an extract of timur (Zanthoxylum armatum), as odor-masking agent. It also relates to a deodorizing product in the form of an aerosol, candle, or electrical or wick fragrance diffuser, containing this composition.
Type:
Grant
Filed:
March 15, 2018
Date of Patent:
May 3, 2022
Assignee:
JAFER ENTERPRISES R&D SL
Inventors:
Thomas Delmas, Antoine Gouteyron, Marion Perez