Abstract: This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a pharmaceutical compound at a target site. More specifically, this invention relates to a controlled release intravaginal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which comprises microspheres encapsulated and/or embedded within a bioerodible polymeric matrix, together the microspheres and the matrix are formed into a caplet and/or tablet.
Type:
Grant
Filed:
February 8, 2013
Date of Patent:
September 13, 2016
Assignee:
University of the Witwatersrand, Johannesburg
Inventors:
Viness Pillay, Yahya Essop Choonara, Felix Mashingaidse, Pradeep Kumar