Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
Type:
Grant
Filed:
October 4, 2019
Date of Patent:
April 20, 2021
Assignee:
ADT Pharmaceuticals, LLC
Inventors:
Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
Abstract: The present invention relates to novel 2,5-dioxoimidazolidin-1-yl-3-phenylurea derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.
Type:
Grant
Filed:
November 9, 2012
Date of Patent:
July 23, 2013
Assignee:
Allergan, Inc.
Inventors:
Richard L. Beard, Vidyasagar Vuligonda, Thong Vu, John E. Donello, Veena Viswanath, Michael E. Garst
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