Abstract: Described herein is a method for creating a channel through a foreign material located in a body of a patient. The foreign material defines a material first surface and a substantially opposed material second surface and the channel extends through the foreign material between the material first and second surfaces. The method uses an apparatus including an electrode, and includes the steps of: positioning the electrode substantially adjacent to the material first surface; energizing the electrode with a radiofrequency current; and using the electrode energized with the radiofrequency current to deliver energy into the foreign material to create the channel. In some embodiments, the patient's body includes a heart defining a septum, the septum defines an aperture extending there-through and the foreign material extends across the aperture to cover the aperture.

Abstract: Described herein is a method for creating a channel through a foreign material located in a septum of a heart at the site of a septal defect. The foreign material defines a material first surface and a substantially opposed material second surface, and the channel extends through the foreign material at least partially between the material first and second surfaces. The method uses an apparatus including an electrode and includes the steps of: positioning the electrode substantially adjacent to the material first surface; energizing the electrode with a radiofrequency current; and using the electrode energized with the radiofrequency current to deliver energy into the foreign material to create the channel.

Abstract: An electrosurgical device for devitalizing tissue including a probe body, equipped with at least one electrode, and a cooling device. The probe body is suitable for generating a heat distribution field by means of a high-frequency current for devitalizing the tissue. The cooling device prevents carbonization of the tissue close to the probe body that would normally occur since the maximum current density occurs here. The electrosurgical device is modified such that the heat distribution over the probe body can be adjusted, allowing adjustment or positioning of a maximum cooling zone within the probe body. This regulation may be accomplished by regulating the inlet pressure of the refrigerant supply to the electrosurgical device.

Abstract: A bipolar clamp for high-frequency surgery, in particular for coagulating tissue, having at least two bipolar clamping parts which are movable relative to one another, defining a grasping region between an open position and a coagulation position (e.g., closed position) and having electrodes for coagulating tissue that is grasped by the clamping parts in the grasping region. The clamping parts are formed of an electrically conductive core which is surrounded by a thin-layer electrical insulation and the electrodes are arranged on the clamping parts as thin pin electrodes that protrude through the thin-layer electrical insulation into the grasping region.

Abstract: A tissue ablation system including numerous components and methods is described herein for encircling target tissue and generating tissue ablation volumes in various biological tissues. The biological tissue includes tissue of a variety of organs of the human body including the liver, spleen, kidney, lung, breast and other organs, but is not so limited. The tissue ablation device comprises an energy source and at least one trocar coupled to the energy source, the trocar having a body, a proximal end, and a distal end. The trocar carries an electrode array that comprises a plurality of electrodes, each electrode of the plurality of electrodes is configured to extend from the trocar when moved from a retracted state to a deployed state, and to have at least one radius of curvature in the deployed state so that the electrode array forms a series of shaped electrodes in the deployed state.

Abstract: A system for treating tissue includes a device including a first member and a second member arranged to move relative to the first member to treat tissue. The system also includes a processor configured to automatically control movement of the second member relative to the first member using position control methodology. A method of treating tissue includes providing a device having a first member and a second member arranged to move relative to the first member, moving the second member relative to the first member, and automatically controlling the movement of the second member using position control methodology.

Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.

Abstract: An endoscopic instrument includes a housing having shaft extending therefrom that defines a longitudinal axis therethrough. The shaft includes an articulating section disposed thereon. The articulating section has a central annulus extending therealong and first and second pluralities of bores. The first plurality of bores configured to receive corresponding tendons therethrough and the second plurality of bores configured to receive corresponding conductive leads therethrough. An end effector assembly operatively connected to a distal end of the shaft including a pair of first and second jaw members. The corresponding conductive leads transition from a first state for enabling articulation of the shaft about the articulating section, to a second state for disabling articulation of the shaft about the articulating section.

Abstract: According to some embodiments, a method of treating conditions affecting a liver of a subject is provided. The method may include delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

Abstract: Systems and methods for endometrial ablation. The systems include a handle and elongated introducer sleeve extending to an expandable working end having a fluid-tight interior chamber. A thin dielectric wall surrounds at least a portion of the interior chamber and has an external surface for contacting endometrial tissue. The thin dielectric wall surrounds a collapsible-expandable frame and receives an electrically non-conductive gas. First and second polarity electrodes are exposed to the interior and exterior of the chamber, respectively. A radiofrequency power source operatively connects to the electrode arrangement to apply a radiofrequency voltage across the first and second electrodes, wherein the voltage is sufficient to initiate ionization of the neutral gas into a conductive plasma within the interior chamber, and to capacitively couple the current in the plasma across the thin dielectric wall to ablate endometrial tissue engaged by the external surface of the dielectric structure.

Abstract: An electrophysiologic catheter with an improved control handle is provided. The catheter includes a heat transfer assembly to better dissipate heat in the control handle. The heat transfer assembly includes a pump, a reservoir containing a coolant, a heat transfer member, and a coolant transport network transporting coolant between at least the reservoir and the heat transfer member. In one embodiment, the heat transfer member is located within the control handle as a heat exchanger on the circuit board to receive the coolant for transferring heat from the integrated circuits to the coolant. In another embodiment, the heat transfer member is located on the circuit board directly surrounding the integrated circuits to internally cool the integrated circuit within the control handle. A second heat transfer member is located outside of the control handle as a heat exchanger.

Abstract: The embodiments herein provide a method and system for generating heat at a target area of a patient's body for treatment of lesions, tumors, cancer cells, body pain and nerve pain. The heat generated inside a target tissue is distributed throughout the target area. The system and method provides a real time monitoring of the generated heat and the temperature of the tissue. The system comprises a radio frequency (RF) antenna/transducer for receiving the generated RF waves from the RF generator. A controller/optimizer is provided for controlling a frequency of the RF waves and a transmission timing of the RF waves. A RF absorber/distributor comprising a plurality of closed loop circuits is provided. A miniaturized thermometer is arranged inside the RF absorber is arranged close to irradiation area for measuring the temperature which is transmitted to the controller. Several needles/probes are implanted at the target location of patient's body.

Abstract: The application relates to an endoscopic surgical instrument, and in particular to an instrument for endoscopic mucosa resection. The instrument includes a device for feeding in at least one liquid (for injection and/or dissection) and a device for high frequency surgery. These devices are combined within a single surgical instrument, in the interest of uniform handling.

Abstract: Ablation electrode assemblies having a longitudinal axis include an electrode core member; an electrode shell; and an irrigant distribution element. The electrode core member comprises a thermal insulator and has a first end; a second end; and at least one irrigation passageway. The electrode shell comprises an electrically conductive material, defines an inner volume, and has a first end; and a second end. The second end of the electrode shell is configured for connection to the first end of the electrode core member. The electrode shell is sufficiently flexible for deflection of the distal end of the electrode shell relative to the longitudinal axis of the ablation electrode assembly. The irrigant distribution assembly comprises a first end; and a second end, wherein the second end of the irrigant distribution element defines a circumferential irrigation port between the irrigant distribution element and the electrode core member.

Abstract: High-strength microwave antenna assemblies and methods of use are described herein. The microwave antenna has a radiating portion connected by a feedline to a power generating source, e.g., a generator. Proximal and distal radiating portions of the antenna assembly are separated by a junction member. A reinforcing member is disposed within the junction member to increase structural rigidity.

Abstract: Disclosed is a spacer, configured to position microwave energy delivery devices, including a housing, with a housing body and a compression body, and at least one compression mechanism. The housing body forms a housing body cavity and a plurality of housing device apertures. The compression body forms a plurality of compression body apertures that each correspond to a housing device aperture. The compression body slideably engages the housing body cavity and at least a portion of the compression body is positioned within the compression body cavity. A compression mechanism is positioned between the housing body and the compression body and configured to provide a biasing force between the housing body and the compression body. In a first position the housing device apertures are misaligned with the compression body apertures and in the second position the housing apertures are aligned with the compression body apertures forming a plurality of aligned apertures.

Abstract: Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

Abstract: A system for providing feedback during an electrosurgical procedure on a target tissue is provided. The system includes an electrosurgical energy source; an electrode probe assembly connected to the electrosurgical energy source, wherein the electrode probe assembly includes at least one electrode assembly having a needle configured to deliver electrosurgical energy to the target tissue; at least one thermal feedback assembly connected to the electrosurgical energy source, wherein each thermal feedback assembly includes at least one temperature sensor assembly; and a hub configured to selectively support the electrode probe assembly and each thermal feedback assembly such that the needle of the electrode probe assembly and each temperature sensor assembly of each thermal feedback assembly are proximate one another when disposed proximate the target tissue.