Abstract: A system for providing feedback during an electro surgical procedure on a target tissue is provided. The system includes an electrosurgical energy source; an electrode probe assembly connected to the electrosurgical energy source, wherein the electrode probe assembly includes at least one electrode assembly having a needle configured to deliver electrosurgical energy to the target tissue; at least one thermal feedback assembly connected to the electrosurgical energy source, wherein each thermal feedback assembly includes at least one temperature sensor assembly; and a hub configured to selectively support the electrode probe assembly and each thermal feedback assembly such that the needle of the electrode probe assembly and each temperature sensor assembly of each thermal feedback assembly are proximate one another when disposed proximate the target tissue.

Abstract: A catheter assembly comprises a deflectable catheter shaft comprising a distal end and a lumen extending therethrough. The catheter assembly further comprises least one pull wire comprising a distal portion comprising a side and a distal end, wherein the side comprises a first side portion and a second side portion. The catheter assembly further comprises a distal pull assembly operatively coupled to the at least one pull wire. The distal pull assembly comprises a longitudinal axis, a first surface, and a second surface. The first side portion of the at least one pull wire is adjacent to the first surface of the distal pull assembly, and the second side portion of the at least one pull wire is adjacent to the second surface of the distal pull assembly.

Abstract: A medical device comprising a cell including an ablation element and a carrier configured to receive at least a portion of said ablation element is disclosed. The medical device further comprises a tube enclosing the cell. At least a portion of the tube includes a membrane and the tube includes at least one hole proximate the ablation element for facilitating fluid flow. The medical device further comprises a fluid inlet for providing fluid to the interior of the tube. A method of using the medical device is also disclosed.

Abstract: A system that interfaces with a workstation endocardial mapping system allows for the rapid and successful ablation of cardiac tissue. The system allows a physician to see a representation of the physical location of a catheter in a representation of an anatomic model of the patient's heart. The workstation is the primary interface with the physician. A servo catheter having pull wires and pull rings for guidance and a servo catheter control system are interfaced with the workstation. Servo catheter control software may run on the workstation. The servo catheter is coupled to an RF generator. The physician locates a site for ablation therapy and confirms the location of the catheter. Once the catheter is located at the desired ablation site, the physician activates the RF generator to deliver the therapy.

Abstract: A device for radio frequency ablation (RFA) of diseased tissue has a mesh or plate with a grid of holes for holding electrodes; a plurality of electrodes with adaptable active tip length; means for visualizing and probing insertion depth of each of the electrodes in the diseased tissue; a switch box, connectable to the electrodes and adapted to distribute current between the electrodes during the RFA process; a control unit for controlling the switch box; and means for monitoring the RFA process. The control unit is adapted to determine groups of electrodes, an electric mode for activation of each group of electrodes, a polarity for electrodes within each group of electrodes, an activation mode for the groups, a time interval and order for activation of the groups, a power output and current strength, and a duration of the RFA process.

Abstract: Apparatus (20) for carrying out a prophylactic or treatment procedure on tissue comprises a device (21) having a chamber (22) and at least one active element such as an electrode (23) within the chamber (22). The chamber (22) has an opening (26) through which tissue is drawn into the chamber (22). Means for drawing the tissue into the chamber may comprise a vacuum lumen with vacuum orifices (25) in the chamber (22). Treatment such as electroporation may be applied to tissue in the chamber (22).

Abstract: Systems and methods for endometrial ablation. The systems include a handle and elongated introducer sleeve extending to an expandable working end having a fluid-tight interior chamber. A thin dielectric wall surrounds at least a portion of the interior chamber and has an external surface for contacting endometrial tissue. The thin dielectric wall surrounds a collapsible-expandable frame and receives an electrically non-conductive gas. First and second polarity electrodes are exposed to the interior and exterior of the chamber, respectively. A radiofrequency power source operatively connects to the electrode arrangement to apply a radiofrequency voltage across the first and second electrodes, wherein the voltage is sufficient to initiate ionization of the neutral gas into a conductive plasma within the interior chamber, and to capacitively couple the current in the plasma across the thin dielectric wall to ablate endometrial tissue engaged by the external surface of the dielectric structure.

Abstract: Apparatus and methods for insulating tissue during therapeutic procedures.

Abstract: Catheters, systems, and methods are provided for performing medical procedures, such as tissue ablation, adjacent the ostia of anatomical vessels, such as pulmonary veins. The catheter comprises an elongated flexible catheter body, which includes a proximal shaft portion and a distal shaft portion, and a tracking element carried by the distal shaft portion. The proximal section is pre-shaped to form a curve having an apex sized to be inserted into the vessel ostium, and a distal section configured to contact the adjacent tissue when the curve apex is inserted within the vessel ostium. The method may comprise inserting the curve apex into the vessel ostium to place the distal section in contact with a first tissue site adjacent the vessel ostium, and determining a location of the tracking element(s) within a coordinate system while the distal section is in contact with the first tissue site.

Abstract: This invention provides a system and method that allows a therapeutic device, such as an atrial fibrillation microwave ablation catheter or ablation tip to be guided to a remote location within a body cavity and then accurately immobilized on the tissue, including that of a moving organ, such as the heart. In various embodiments, the system and method also enables accurate movement and steering along the tissue, while in engagement therewith. Such movement and engagement entails the use of vacuum or microneedle structures on at least two interconnected and articulated immobilizers that selectively engage to and release from the tissue to allow a crawling or traversing walking across the organ as the therapeutic catheter/tool tip applies treatment (AGE devices). In further embodiments that lack a movement capability (AID devices), the immobilizers allow a predetermined position for the introduced device to be maintained against the tissue while a treatment is applied to the location adjacent thereto.

Abstract: Methods, systems and devices for endometrial ablation. In accordance with a method, a working end of an RF ablation device is positioned in a patient uterus to contact endometrial tissue, the working end comprising a dielectric wall capable of non-expanded and expanded shapes. An indicator mechanism is operatively coupled to the wall and configured to indicate non-expanded and expanded shapes of the wall. An expandable member, such as a balloon, is provided that expands to close the cervical canal during ablation.

Abstract: An end effector assembly for use with an electrosurgical instrument is provided. The end effector assembly has a first jaw member having a first pair of tissue contacting surfaces and an insulator disposed therebetween. The end effector assembly also has a second jaw member that includes a second pair of tissue contacting surfaces, a pair of insulators disposed between the second pair of tissue contacting surfaces, and a cutting element disposed between the pair of insulators. The relative movement of the first jaw member toward the second jaw member causes the insulator of the first jaw member and the pair of insulators of the second jaw member to pinch tissue disposed between the first jaw member and the second jaw member.

Abstract: Nanosecond pulsed electric field (nsPEF) parameters for destroying tumors with a single treatment are described. A nsPEF generator may be used with an electrode assembly to apply the pulses to one or more tumors where the parameters for the nsPEF are optimized for treating such tumors.

Abstract: A French door oven includes a body defining a cooking chamber with an open mouth. First and second doors are respectively connected to the body adjacent opposite first and second opposite lateral sides of the mouth and are adapted to pivot about respective first and second vertical pivot axes between an opened position in which the first and second doors are pivoted away from the mouth and a closed position in which the first and second doors cover the mouth and define a seam between their adjacent respective inner edges. The oven includes a door movement control system for controlling movement of the doors between their opened and closed positions. The door movement control system includes a door movement control plate including a door movement slot including an inner portion and an outer portion, the outer portion closer to the mouth than the inner portion.

Abstract: Systems and methods for endometrial ablation. The systems include a handle and elongated introducer sleeve extending to an expandable working end having a fluid-tight interior chamber. A thin dielectric wall surrounds at least a portion of the interior chamber and has an external surface for contacting endometrial tissue. The thin dielectric wall surrounds a collapsible-expandable frame and receives an electrically non-conductive gas. First and second polarity electrodes are exposed to the interior and exterior of the chamber, respectively. A radiofrequency power source operatively connects to the electrode arrangement to apply a radiofrequency voltage across the first and second electrodes, wherein the voltage is sufficient to initiate ionization of the neutral gas into a conductive plasma within the interior chamber, and to capacitively couple the current in the plasma across the thin dielectric wall to ablate endometrial tissue engaged by the external surface of the dielectric structure.

Abstract: A portable electrosurgical system (100) for treating biological tissue with microwave radiation (e.g. having a frequency between 500 MHz and 60 GHz) is disclosed. The system comprises a hand-held microwave sub-assembly (102) which generates and amplifies a microwave signal (which may be continuous or modulated) for treatment and includes a treatment antenna (116) for delivering the radiation. Diode detectors (120, 122) in the sub-assembly (102) may detect forward and reflected power levels to enable determination of net delivered power. A dynamic impedance matching system may be provided to match energy developed by amplifiers (110, 112) in the sub-assembly (102) to the biological tissue load. A tuning filter (144) and couplers (146, 148, 150, 152) for extracting magnitude and phase information from the microwave signal are thus provided in the sub-assembly.

Abstract: A system and method for resecting a valve in a patient, in which the system includes: a proximal frame and a distal frame opposite the proximal frame, each frame including a plurality of interconnectable frame segments, in which the proximal and distal frames are separated by an adjustable distance and positionable on opposite sides of the valve; an electrode, adjacent to the valve on at least one of the proximal and distal frames, that electrosurgically resects valve tissue; a proximal chamber and a distal chamber coupled to the proximal and distal frames, respectively, that allow passage of fluid and captures at least a portion of resected valve tissue, in which each chamber selectively operates in one of a radially collapsed mode and a radially expanded mode; and a drive system that adjusts the distance between the proximal and distal frames.

Abstract: The present invention is a device and method of using a variety of laparoscopic or NOTES surgical tools at a confined or inaccessible space e.g., an intra-abdominal surgical and NOTES tool inserted through a single incision through the skin or hollow viscus. Generally, the laparoscopic or NOTES surgical devices include a device body having a first side and a second side, wherein the first side includes a positioning mechanism and the second side includes one or more of a variety of laparoscopic or NOTES tool.

Abstract: A system for providing feedback during an electrosurgical procedure on a target tissue is provided. The system includes an electrosurgical energy source; an electrode probe assembly connected to the electrosurgical energy source, wherein the electrode probe assembly includes at least one electrode assembly having a needle configured to deliver electrosurgical energy to the target tissue; at least one thermal feedback assembly connected to the electrosurgical energy source, wherein each thermal feedback assembly includes at least one temperature sensor assembly; and a hub configured to selectively support the electrode probe assembly and each thermal feedback assembly such that the needle of the electrode probe assembly and each temperature sensor assembly of each thermal feedback assembly are proximate one another when disposed proximate the target tissue.

Abstract: A method of performing cryotherapy on a patient can include positioning an outer surface of a distal portion of a cryotherapy catheter in contact with body tissue to be treated; performing a treatment phase, including regulating a temperature of the outer surface at a treatment value for a first period of time; performing a recovery phase comprising allowing the temperature of the outer surface to warm up to a recovery value that is higher than treatment value but substantially lower than a normal body temperature of the patient; and performing one or more additional treatment phases for a second period of time. Each of the first and second periods of time can be selected to allow a cold front having a cold front temperature to propagate from the outer surface and through a therapeutic portion of a thickness of the body tissue, but not substantially beyond the thickness.