Abstract: Disclosed is a method and system for navigating an instrument relative to a subject. A reference device can be associated with the subject. The reference device can be moved while maintaining or allowing registration with an image space.

Abstract: Systems and methods are provided in which an intraoperative video feed is augmented with one or more virtual display features based on a detected orientation and position of the tracked medical instrument. In some example embodiments, the virtual display features may be employed to represent, in an augmented video feed, information associated with a previously-detected intraoperative position and orientation of the tracked medical instrument. The virtual display element may be employed, for example, to facilitate the alignment of an untracked medical instrument with a previously determined intraoperative position and orientation of the tracked medical instrument. In other example embodiments, the virtual display element may be dynamically displayed in a fixed spatial relationship relative to the tracked medical instrument.

Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses, Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.

Abstract: An endoscope system includes an insertion section, a first active bending section, a second active bending section, a position-information acquiring section, a first control section, a second control section, and a third control section. The first control section controls, based on a detection result of the position-information acquiring section, a first driving section of the first active bending section such that a first end portion of a first tubular section of the first active bending section moves away from a center point. The first control section controls a second driving section of the second active bending section such that a second end portion of a second tubular section of the second active bending section approaches the center point. The third control section controls the first driving section such that force in a direction of bending the first tubular section in a first bending operation acts on the first end portion.

Abstract: Apparatus and methods are provided for using catheters to increase the accuracy of anatomical maps in the setting of patient movement.

Abstract: Disclosed is a system for assisting in guiding and performing a procedure on a subject. The subject may be any appropriate subject such as inanimate object and/or an animate object. The guide and system may include various manipulable or movable members and may be registered to selected coordinate systems.

Abstract: Transrectal ultrasound probe for boiling histotripsy ablation of prostate are presented herein. In one embodiment, a method for a transrectal ultrasound treatment uses high intensity focused ultrasound (HIFU). The method includes: generating a boiling histotripsy (BH) therapy ultrasound by a therapy transducer in a frequency range of 1 MHz to 2.8 MHz and a surface intensity range of 10 W/cm2 to 80 W/cm2. The therapy transducer may be about 50 mm long and about 35 mm wide. The method also includes applying the therapy ultrasound by directing ultrasound pulses having ultrasound shock waves to a target tissue at a focal depth of 2.5 cm to 5.5 cm; generating at least one ?m-scale vapor bubble at a target region; growing the at least one vapor bubble to at least one mm-scale bubble; and mechanically disintegrating a surrounding tissue by interactions between mm-scale bubbles and the ultrasound shock waves within a pulse.

Abstract: A transducer array includes at least one annular shear wave generation transducer that defines an interior area, the at least one annular shear wave generation transducer being configured to generate a shear wave excitation to a region of interest such that the shear wave excitation excites at least a part of a corresponding cylindrical portion of the region of interest and shear waves propagating from the cylindrical portion of the region of interest constructively interfere in an interior region of the cylindrical portion of the region of interest; and at least one tracking transducer positioned in the interior area of the at least one annular shear wave generation transducer, the at least one tracking transducer being configured to detect a shear wave in the interior region of the region of interest.

Abstract: A medical procedure system, including a medical instrument to be inserted into a body part, and including position-tracking transducers to provide position signals, a distal end, and at least one radiopaque marker, a position tracking sub-system to compute a position including at least one location and orientation of the distal end in a position-tracking sub-system coordinate frame responsively to the position signals, a fluoroscope to capture fluoroscopic images of an interior of the body part and the radiopaque marker(s), and a registration sub-system to render, to a display, the captured fluoroscopic images including at least one marker-image of the radiopaque marker(s), and at least one graphical representation indicative of the computed position of the distal end, receive user-alignment input aligning the graphical representation(s) with the marker-image(s), and register the position-tracking sub-system coordinate frame with a coordinate frame of the fluoroscope responsively to the received user-alignmen

Abstract: A system for tracking a piece of medical equipment intraoperatively using a collinear array of fiducial markers positioned at known fixed distances relative to each other on the medical equipment and a camera capturing an image on a single image plane. Representations of the fiducial markers are segmented from a captured image, 3D orientation and position of the medical equipment are calculated using the segmented representations, and the orientation and position of the medical equipment are tracked relative to the camera. The orientation and position of the medical equipment may be registered within a 3D virtual space. The system may be used as part of a surgical navigation system.

Abstract: A device for shock wave production to treat a patient's body comprises a base with a condenser as power supply, an applicator having a pad, at least one piezo-element configured to generate a shock wave in response to a pulse of electric current having a pulse width, an acoustic lens configured to focus the shock wave, and a coil configured to increase the pulse width of the pulse of electric current.

Abstract: Various approaches for computationally generating a protocol for treatment of one or more target BBB regions within a tissue region of interest using a source of focused ultrasound include specifying (i) settings of sonication parameters for applying one or more sequence of sonications to the target BBB region using the source of focused ultrasound and (ii) a characteristic of microbubbles selected to be administered into the target BBB region; electronically simulating treatment in accordance with the protocol at least in part by computationally executing the sequence(s) of sonications and computationally administering the microbubbles having the characteristic; and computationally predicting a tissue disruption effect of the target BBB region resulting from the treatment.

Abstract: An ultrasonic echogenic device (100) includes a base layer (1), an echogenic layer (2) covering the base layer (1) and adhered to the base layer (1) at least by a separate lower adhesive (4), an outer layer (3) covering the echogenic layer (2) and adhered to the echogenic layer (2) at least by a separate upper adhesive (5), wherein the ultrasonic echogenic device (100) is configured such that a rough interface is provided at a position where the echogenic material of the echogenic layer (2) contacts at least the upper surface of the upper adhesive (5) and the lower adhesive (4), and the outer surface of the outer layer (3) at least partially follows an undulation of the rough interface. An ultrasonic echogenic device (100) with a simple structure and easily formed is obtained.

Abstract: To provide an ultrasonic transmission instrument that can uniformly transmit ultrasonic waves in each direction around the instrument, even when the instrument is made of a material through which the ultrasonic waves cannot be transmitted. In an ultrasonic transmission instrument according to the invention, a light transmission member is disposed at an emission end of an optical waveguide, and an outer peripheral member covers an outer periphery of the light transmission member and is made of a light absorbing material.

Abstract: A method includes placing a set of electrodes on a body surface of a patient's body. The method also includes digitizing locations for the electrodes across the body surface based on one or more image frames using range imaging and/or monoscopic imaging. The method also includes estimating locations for hidden ones of the electrodes on the body surface not visible during the range imaging and/or monoscopic imaging. The method also includes registering the location for the electrodes on the body surface with predetermined geometry information that includes the body surface and an anatomical envelope within the patient's body. The method also includes storing geometry data in non-transitory memory based on the registration to define spatial relationships between the electrodes and the anatomical envelope.

Abstract: Apparatus and methods are provided for applying ultrasound pulses into tissue or a medium in which the peak negative pressure (P?) of one or more negative half cycle(s) of the ultrasound pulses exceed(s) an intrinsic threshold of the tissue or medium, to directly form a dense bubble cloud in the tissue or medium without shock-scattering. In one embodiment, a microtripsy method of Histotripsy therapy comprises delivering an ultrasound pulse from an ultrasound therapy transducer into tissue, the ultrasound pulse having at least a portion of a peak negative pressure half-cycle that exceeds an intrinsic threshold in the tissue to produce a bubble cloud of at least one bubble in the tissue, and generating a lesion in the tissue with the bubble cloud. The intrinsic threshold can vary depending on the type of tissue to be treated. In some embodiments, the intrinsic threshold in tissue can range from 15-30 MPa.

Abstract: The invention generally relates to intravascular imaging system and particularly to processing in multimodal systems. The invention provides an imaging system that splits incoming image data into two signals and performs the same processing step on each of the split signals. The system can then send the two signals down two processing pathways. Methods include receiving an analog image signal, transmitting the received signal to a processing system, splitting the signal to produce a first image signal and a second image signal, and performing a processing operation on the first image signal and the second image signal. The first and second signal include substantially the same information as one another.

Abstract: Techniques are disclosed for positioning a patient couch in a patient receiving area of a magnetic resonance device for a magnetic resonance examination, which includes starting an introduction of the patient couch into the patient receiving area, acquiring monitoring data within an acquisition area of at least one sensor unit by means of the at least one sensor unit during the introduction of the patient couch into the patient receiving area, evaluating the monitoring data with respect to a selected area of an examination object and/or a selected area of the patient couch, and positioning the patient couch within the patient receiving area in dependence on an acquisition of the selected area of the examination object and/or the selected area of the patient couch in the monitoring data.

Abstract: A bio-optical measuring apparatus according to an embodiment of the present disclosure includes a light source that emits coherent light; and three or more optical receivers that receive reflected light from a living body, of light outputted from the light source toward the living body. The bio-optical measuring apparatus further includes a signal processing unit that obtains a low-noise signal by performing averaging processing based on detection signals outputted from the respective optical receivers in response to reception of the reflected light.

Abstract: A system and a method are respectively for positioning an examination object and evaluation of an image with respect to a positioning of a breast of an examination object in relation to an x-ray device. In an embodiment, the system includes an x-ray device including at least one compression device to fix a breast of the examination object; at least one camera, arranged in relation to the x-ray device such that images are acquirable via the at least one camera, the images showing a current positioning of the breast of the examination object in relation to the x-ray device; and at least one display device, embodied to display the images.