Abstract: The present invention relates to 1,2,3,4,5,6-hexahydro-2,6-methano-3 -benzazocin-10-ols of general formula 1
wherein the groups R1, R2, R3, R4, R5, R6, R7, R8 and R9 have the meanings as set forth herein, processes for preparing them, pharmaceutical compositions thereof and their use in treating or preventing a disease or disorder by blocking the voltage-dependent sodium channel.
Type:
Grant
Filed:
January 30, 2003
Date of Patent:
January 27, 2004
Assignee:
Boehringer Ingelheim Pharma GmbH & Co. KG
Inventors:
Adrian Carter, Helmut Ensinger, Matthias Grauert, Detlef Andre Stiller, Thomas Weiser