Abstract: A focused extracorporeal shock wave therapy (f-ESWT) system includes an f-ESWT device and a plurality of interchangeable standoff structures. The f-ESWT device includes a housing. The f-ESWT device is configured to generate a focused shock wave as a combination of a plurality of individual shock waves. Each standoff structure is configured for removable connection to the housing to receive and to transmit the plurality of individual shock waves. Each standoff structure of the plurality of interchangeable standoff structures includes a rigid exterior shell defining a shell space, and an elastomeric interior at least partially located in the shell space. The plurality of individual shock waves is transmitted through the rigid exterior shell and the elastomeric interior of a selected standoff structure of the plurality of interchangeable standoff structures that is removably connected to the housing.

Abstract: An imaging station/booth for automated total body imaging having a small footprint and capable of quickly, efficiently, effectively, and consistently capturing multiple body images of a user or patient over time with minimal assistance from medical staff.

Abstract: Implant device recharging methods, devices, and systems. The implantable devices that are recharged can include one or more sensors. The implantable devices can include one or more receive transducers. A recharging catheter can emit energy to the one or more receive transducers to recharge an implantable device power source.

Abstract: A focused extracorporeal shock wave therapy (f-ESWT) device includes a handheld housing, a battery, and a transducer assembly. The battery is located in the handheld housing. The transducer assembly is located in the handheld housing and is operably connected to the battery. The transducer assembly is configured to generate a focused shock wave using electrical energy from the battery.

Abstract: A handheld focused extracorporeal shock wave therapy (f-ESWT) device includes a plurality of piezoelectric elements, a power supply circuit, and a plurality of driver circuits. The piezoelectric elements are each configured to generate an individual shock wave. The power supply circuit is configured to output a first DC voltage and a second DC voltage. The first DC voltage greater than the second DC voltage. The driver circuits are each operably connected to the first DC voltage, the second DC voltage, and to a corresponding piezoelectric element of the plurality of piezoelectric elements. Each driver circuit includes a switching element electronically configurable in an open state and in a closed state. When the switching element is in the open state, the first DC voltage and the second DC voltage are applied to the corresponding piezoelectric element to pre-charge the corresponding piezoelectric element with a DC pre-charge voltage having a first polarity.

Abstract: Functional Magnetic Resonance Imaging (fMRI) reconstruction of brain-state-specific images from slow, anatomical MRI image data. In an embodiment, for each of a plurality of stimulation sequences, an fMRI apparatus is controlled to capture a set of whole-brain image data of the same region of a subject's brain according to the stimulation sequence. Each stimulation sequence is configured to induce each of a plurality of brain states in a different sequence than any of the other stimulation sequences, and each set of whole-brain image data comprises a plurality of sub-acquisition segments. For each set of whole-brain image data, each sub-acquisition segment in the set is associated with one of the brain states. Then, for each of the brain states, a whole-brain image is reconstructed from a subset of the sub-acquisition segments, in each captured set of whole-brain image data, that are associated with the brain state.

Abstract: Provided is a surgical method. The method includes detecting a location of a reference unit having a trackable element with a detector, the detector configured to provide at least one signal corresponding to a detected location of at least the reference unit's trackable element; accessing a computer-readable reconstruction of the being's anatomy; accessing a computer-readable reconstruction of an implant; detecting a location of a pointer tool comprising a trackable element with the detector, where the pointer tool is associated with a location of an anatomical feature of interest; accessing at least one computer-readable reconstruction of a trace, the trace corresponding to a geometry of the anatomical feature of interest; and superimposing the at least one updatable, computer-readable trace on the second computer-readable reconstruction of the implant.

Abstract: A surgical instrument assembly configured to display a representation of the surgical instrument relative to a trajectory (e.g., a desired trajectory for drilling into an implant) based image data from an image sensor (e.g., a camera). For example, the surgical instrument assembly may be configured to determine a desired trajectory (e.g., a central axis of a distal hole of an intramedullary nail) based on X-ray image data representing at least one fiducial marker (e.g., an array of ArUco markers) and representing an anatomical structure and/or an implant. The surgical instrument assembly may in real time display a representation of the orientation and/or position of the surgical instrument (e.g., the orientation and position of a drill bit of the surgical instrument) in relation to the desired trajectory based on image sensor data that is generated based on an orientation of the at least one fiducial marker detected by an image sensor.

Abstract: In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement.

Abstract: A C-arm, or a mobile intensifier device, is one example of a medical imaging device that is based on X-ray technology. Because a C-arm device can display high-resolution X-ray images in real time, a physician can monitor progress at any time during an operation, and thus can take appropriate actions based on the displayed images. Monitoring the images, however, is often challenging during certain procedures, for instance during procedures in which attention must be paid to the patient's anatomy as well as a medical imaging device display. In an example, a surgical instrument assembly includes a processor, a surgical instrument configured to operate on an anatomical structure, and a display coupled to the processor and attached to the surgical instrument. The display can be configured to display visual information comprising X-ray images generated by a medical imaging device.

Abstract: Aspects of positioning devices, methods, and systems are disclosed. An exemplary method comprises: moving a distal end of a tube into a body, the tube including a lumen and a shaft in the lumen, the shaft having a transducer; sending a first signal to the transducer; passing, with the transducer, in response to the first signal, a wave energy into the body; receiving, with the transducer, a reflected portion of the wave energy; generating, with the transducer, a second signal in response to the reflected portion of the wave energy; determining, with a processor, an indicia of the body in response to the second signal; and identifying, with the indicia, a targeted issue in the body; positioning the distal end of the tube at the targeted tissue in response to the indicia; and removing a portion of the targeted tissue with the distal end of the tube.

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

Abstract: The invention relates to a tracking reference, comprising: a reference array (1) featuring a positionally fixed arrangement of at least two tracking markers (3); and an interface (4A) for detachably coupling the reference array (1) to a base member (2), wherein the interface (4A) comprises at least one supporting surface (5) for contacting the base member (2), wherein the interface (4A) comprises magnetic means (6) which generate a force at the reference array, wherein the force (F) is directed away from the supporting surface (5).

Abstract: A method of fetal ultrasound monitoring includes detecting contact of a first ultrasound transducer to a mother's abdomen based on input from a contact sensor in the first ultrasound transducer. A first transducer identifier is received from the first ultrasound transducer, and then the first transducer identifier is correlated with a first transducer label. A first heart rate is measured based on output of an ultrasound device in the first ultrasound transducer, and a heart rate indicator is displayed accordingly. A position of the first ultrasound transducer is identified in a two-dimensional plane, and the first transducer label is displayed on an abdomen image based on the first position.

Abstract: An ultrasound apparatus includes a probe to acquire ultrasound data from an object; a communicator; a display; and a processor to generate a first ultrasound image based on the ultrasound data; display the first ultrasound image on the display; control the communicator to transmit the first ultrasound image to an external device so that the first ultrasound image is displayed on the external device; generate a second ultrasound image based on the ultrasound data and a control command received from the external device, the control command being based on a touch input with respect to the first ultrasound image displayed on the external device; display the second ultrasound image on the display; and control the communicator to transmit the second ultrasound image to the external device so that the second ultrasound image is displayed on the external device.

Abstract: An adaptive real-time radial k-space sampling trajectory (ARKS) can respond to a physiologic feedback signal to reduce motion effects and ensure sampling uniformity. In this adaptive k-space sampling strategy, the most recent signals from an ECG waveform can be continuously matched to the previous signal history, new radial k-space locations were determined, and these MR signals combined using multi-shot or single-shot radial acquisition schemes. The disclosed methods allow for improved MRI imaging.

Abstract: Presented herein are systems and methods for tomographic imaging of a region of interest in a subject using short-wave infrared light to provide for accurate reconstruction of absorption maps within the region of interest. The reconstructed absorption maps are representations of the spatial variation in tissue absorption within the region of interest. The reconstructed absorption maps can themselves be used to analyze anatomical properties and biological processes within the region of interest, and/or be used as input information about anatomical properties in order to facilitate data processing used to obtain images of the region of interest via other imaging modalities. For example, the reconstructed absorption maps may be incorporated into forward models that are used in tomographic reconstruction processing in fluorescence and other contrast-based tomographic imaging modalities.

Abstract: An imaging method may include obtaining imaging data associated with a region of interest (ROI) of an object. The imaging data may correspond to a plurality of time-series images of the ROI. The imaging method may also include determining, based on the imaging data, a data set including a spatial basis and one or more temporal bases. The spatial basis may include spatial information of the imaging data. The one or more temporal bases may include temporal information of the imaging data. The imaging method may also include storing, in a storage medium, the spatial basis and the one or more temporal bases.

Abstract: A method for predicting clinical severity of a neurological disorder includes steps of: a) identifying, according to a magnetic resonance imaging (MRI) image of a brain, brain image regions each of which contains a respective portion of diffusion index values of a diffusion index, which results from image processing performed on the MRI image; b) for one of the brain image regions, calculating a characteristic parameter based on the respective portion of the diffusion index values; and c) calculating a severity score that represents the clinical severity of the neurological disorder of the brain based on the characteristic parameter of the one of the brain image regions via a prediction model associated with the neurological disorder.

Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.