Abstract: A tire air pressure monitoring system includes: a data acquisition unit that acquires tire air pressure data at each fixed detection period; a storage unit that stores newly acquired air pressure data P(0), and air pressure data P(1) to P(N) acquired 1 to N periods prior to the air pressure data P(0); a determination unit that determines a state in which air pressure has decreased, on the basis of air pressure data; and a communication unit that transmits a determination result of the determination unit to an external device, in which the determination unit compares each piece of the air pressure data P(1) to P(n) with the air pressure data P(0) to calculate decrease values, compares the decrease values with a preset first threshold value (th1), and determines that tire air pressure is decreasing when at least one decrease value is greater than or equal to the first threshold value.

Abstract: Methods, systems, computer-readable media, and apparatuses for performing, providing, managing, executing, and/or running a simulation are presented. In one or more embodiments, a computing device may receive one or more changes associated with one of a plurality of entities being simulated. The computing device may determine, based on the one or more changes, one or more component updates associated with the one of the plurality of entities, and determine one or more authority change events occurred on one or more components of the one of the plurality of entities. The computing device may further determine that one or more interest query change events occurred and that one or more interest view change events occurred. The computing device may further determine one or more worker protocol operations, and synchronize, based on the one or more worker protocol operations, view changes with one or more interested workers.

Abstract: A semiconductor device includes a detector mounted on a base substrate and including a pressure detector to detect pressure, a base portion on the base substrate where the detector is buried, a protruding portion protruding upward from the base portion and including an exposure hole which causes the pressure detector to be exposed upward, and a lid supported by an upper surface of the protruding portion to close the exposure hole. An outer circumferential portion of the lid extends outward from the protruding portion in plan view. The lid includes a slit that is open to an outer side surface and causes the exposure hole to communicate with outside sideward of the semiconductor device.

Abstract: Embodiments relate to a semiconductor structure and a fabrication method. The method includes: providing a substrate, where a first trench is formed in the substrate; forming a first dielectric layer and a protective material layer in the first trench, where the first dielectric layer is positioned between the protective material layer and the substrate, and an upper surface of the first dielectric layer is lower than an upper surface of the substrate, to expose a portion of a side wall of the first trench; forming a second dielectric layer on the exposed side wall of the first trench; and filling the second trench to form a work function structure, where the work function structure includes a first work function layer and a second work function layer, where the second work function layer is positioned on an upper surface of the first work function layer.

Abstract: The invention refers to a composite wavelength converter (1) for an LED (100), comprising a substrate (10) and an epitaxial film (20) formed by liquid phase epitaxy on the top and bottom of the substrate (10). Furthermore, the invention refers to a method of preparation of a composite wavelength converter (1) for an LED (100). Furthermore, the invention refers to a white LED light source comprising an LED (100) and an inventive composite wavelength converter (1) mounted on a light emitting surface of the LED (100).

Abstract: Provided is a method for constructing a gE protein-deleted pseudorabies virus (PRV) strain using an adenine base editor (ABE) and use thereof. The method includes: designing an sgRNA sequence using the ABE with a start codon of the gE gene in a PRV as a target site, ligating an enzyme-digested fragment to a double-stranded DNA fragment with sticky ends to obtain a ligation product; and transforming the ligation product into a competent cell to allow plate screening and culture, selecting a resulting positive bacterial strain to allow expanded culture, and extracting a plasmid from a resulting positive bacterial solution; and transferring the plasmid into a target cell to allow the transfection for 24 h, collecting a resulting virus liquid, and centrifuging the virus liquid to collect a resulting supernatant.

Abstract: The present disclosure relates to the field of biomedicine, and in particular, to an improved mutant of a respiratory syncytial virus (RSV) fusion (F) protein and uses thereof. The mutant can form a trimeric structure without introducing a heterologous trimerization domain. Meanwhile, through mutation designs such as releasing internal electrostatic repulsion, deleting the furin cleavage site, truncating the C-terminal domain, and introducing interchain disulfide bonds, the protein is stabilized in the pre-fusion conformation and exhibits enhanced stability. The mutant in the present disclosure is highly immunogenic when used as a vaccine or a vaccine component and can induce the production of a high level of neutralizing antibodies in the immunized animal, which can be used in the preparation of a vaccine for the prevention or treatment of RSV infection, and can also be used as a reagent for the detection of RSV.

Abstract: A combustion device includes: a burner plate facing a combustion chamber; a plurality of injection hole groups formed in the burner plate so as to have an annular shape; and a slit having an annular shape and formed between the plurality of injection hole groups.

Abstract: Systems and methods for modeling gas desorption in a subterranean reservoir include measuring a gas sorption parameter using a crushed core sample from the subterranean reservoir; computing a gas storage capacity of the subterranean reservoir at an initial reservoir pressure based on the gas sorption parameter; generating a three-dimensional (3D) distribution of total organic carbon (TOC) in the subterranean reservoir; estimating a 3D distribution of original adsorbed gas in place of the subterranean reservoir by correlating the gas storage capacity with the 3D distribution of TOC; and predicting the amount of gas desorbed from the subterranean reservoir as the reservoir is depleted.

Abstract: The present invention provides an engineered T cell receptor (TCR) comprising at least one of the following amino acid residues: L96 of the ? chain; R9 of the ? chain; Y10 of the ? chain; T24 of the ? chain; V19 of the ? chain; T20 of the ? chain; M50 of the ? chain; T5 of the ? chain; Q8 of the ? chain; S86 of the ? chain; F39 of the ? chain; D55 of the ? chain; R43 of the ? chain; A66 of the ? chain; V19 of the ? chain; L21 of the ? chain; L103 of the ? chain; T3 of the ? chain; S7 of the ? chain; P9 of the ? chain; M11 of the ? chain; A16 of the ? chain; T18 of the ? chain; L21 of the ? chain; S22 of the ? chain; D26 of the ? chain; F40 of the ? chain; S47 of the ? chain; R48 of the ? chain; Q49 of the ? chain; I51 of the ? chain; L52 of the ? chain; V53 of the ? chain; T67 of the ? chain; E68 of the ? chain; N74 of the ? chain; F76 of the ? chain; N79 of the ? chain; Q81 of the ? chain; A83 of the ? chain; K90 of the ? chain; S92 of the ? chain; D93 of the ? chain; and M101 of the ? chain; wherein the at

Abstract: The present invention relates to a VHH antibody that binds to at least one fungal species and to compositions containing the same. The VHH antibody of the current invention comprises a complementarity determining region 1 (CDR1) region having the amino acid sequence set out in SEQ ID NO: 3; a CDR2 region having the amino acid sequence set out in SEQ ID NO: 4; and a CDR3 region having the amino acid sequence set out in SEQ ID NO: 5. The invention also relates to use of the composition as an anti-fungal agent. The invention further relates to agrochemical compositions and methods of using the same. Additionally, the invention relates to a transgenic plant, plant part, seed, or plant cell. The invention further relates to polynucleotides encoding said VHH antibody. Finally, the invention relates to a method of manufacturing a variant VHH antibody.

Abstract: Techniques for updating hydrocarbon parameters include identifying well data associated with wells formed in subterranean formations of a hydrocarbon reservoir; determining a data density value for each well; assigning each well into a pressure grouping based on a wellbore pressure similarity of the well relative to an initial pattern well; generating a two-dimensional (2D) model of the hydrocarbon reservoir; converting the 2D model into a three-dimensional (3D) model of the hydrocarbon reservoir; and updating a permeability or a porosity associated with a grid cell of the 3D model.

Abstract: A method of wafer bonding includes: forming a first hole in a first insulation layer disposed over a first substrate; performing a first deposition-self-etch process to deposit a first conductive material in the first hole to form a first conductive plug; forming a second hole in a second insulation layer disposed over a second substrate; performing a second deposition-self-etch process to deposit a second conductive material in the second hole to form a second conductive plug; and bonding the first conductive plug with the second conductive plug to form a first grain fusion layer between the first conductive plug and the second conductive plug.

Abstract: A memory device includes a first memory cell. The first memory cell includes: a first conductor structure extending along a lateral direction; a first memory film comprising a first portion wrapping around a first portion of the first conductor structure; and a first semiconductor film wrapping around the first portion of the first memory film. A second conductor structure extends along a vertical direction and is coupled to a first end portion of the first semiconductor film along the lateral direction. A third conductor structure extends along the vertical direction and is coupled to a second end portion of the first semiconductor film along the lateral direction.

Abstract: Disclosed is an image sensor including a first substrate having first and second surfaces opposite to each other and including a pixel array area that includes unit pixel regions, a pad area that surrounds the pixel array area, and an optical black area between the pixel array area and the pad area, a dielectric pattern on the first surface of the first substrate, and a light-shield pattern on a top surface of the dielectric pattern on the optical black area. The first substrate includes first and second trenches recessed from the first surface. The dielectric pattern includes a first part filling the first trench and defining the unit pixel regions, a second part filling the second trench, and a third part on the first surface of the first substrate and connected to the first and second parts.

Abstract: A method for digitally designing a support with the shape of a fibrous blank obtained by three-dimensional weaving intended to form a fibrous preform of a turbine engine blade or propeller after shaping and compaction in a mold, includes providing a set of points representative of a face of the fibrous blank, the face being intended to form the root of the blade or the propeller and a portion of an aerodynamic profile of the blade or the propeller, generating a web connecting the points of the set of points, and digitally designing the support including at least an imprint of the fibrous blank having the shape of the generated web.

Abstract: A method for measuring anti-PAD2 antibodies in a subject with an inflammatory or autoimmune disease, and to determine if the subject has a better prognosis for developing a more severe form of inflammation based on anti-PAD2 antibody levels. Methods for the therapeutic use of anti-PAD2 antibodies are also described.

Abstract: A display device includes a display panel, a first insulating layer on the display panel and having a first refractive index, and a second insulating layer on the first insulating layer and having a second refractive index. The display panel includes a pixel definition layer in which a plurality of emission openings are defined, and a plurality of light emitting elements that respectively correspond to the plurality of emission openings. The first insulating layer has a plurality of openings that correspondingly overlap the plurality of emission openings. Each of the plurality of emission openings extends in an extending direction. Each of the plurality of openings extends in a direction that intersects an extending direction of an overlapped emission opening.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: The subject matter described herein relates to a process suitable for the production of an implantable medical device by means of a 3D printer. The process includes identifying an intended implant area for the medical device, collecting, in a non-invasive manner, a set of physiological data corresponding to the local anatomy of said intended implant area of the patient, noninvasively taking measurements from the set of physiological data of the patient with the aid of an analysis tool, and adding the characteristics of the medical device, which are specific to additive manufacturing, to thus generate a 3D model of the medical device to be produced. The process further includes exporting the 3D model of the medical device to be produced to the 3D printer suitable for printing a shape-memory material in which the parameters of the 3D printer are adapted to the geometry of the medical device.