Patents Examined by Andrea D. S{umlaut over (m)}all
  • Cyclic AMP-specific phosphodiesterase inhibitors
    Patent number: 6569890
    Abstract: Pyrrole compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: May 27, 2003
    Assignee: Icos Corporation
    Inventors: Timothy J. Martins, Kerry W. Fowler, Amy Oliver, Carmen C. Hertel